id:"swepub:oai:prod.swepub.kib.ki.se:142394741"
Search: id:"swepub:oai:prod.swepub.kib.ki.se:142394741" > Increased risk for ...
- 1 of 1
- Previous record
- Next record
- To hitlist
Increased risk for tooth extraction in primary hyperparathyroidism and hypercalcemia: a population study
-
- Koman, A (author)
- Karolinska Institutet
-
- Nasman, P (author)
- Karolinska Institutet
-
- Discacciati, A (author)
- Karolinska Institutet
- show more...
- show less...
- (creator_code:org_t)
- 2019-12-02
- 2020
- English.
- In: Clinical oral investigations. - : Springer Science and Business Media LLC. - 1436-3771 .- 1432-6981. ; 24:8, s. 2755-2761
- Journal article (peer-reviewed)
Abstract
Subject headings
Close
- The aim of this study was to analyze dental comorbidities in untreated primary hyperparathyroidism (pHPT). Patients with pHPT subjected to parathyroidectomy (PTX) at Karolinska University Hospital, Stockholm, during 2011–2016 (n = 982) were selected from the Scandinavian Quality Register of Thyroid, Parathyroid and Adrenal surgery and compared to a general population cohort (n = 2944), matched for age and gender. Dental data was obtained from the Swedish Dental Health Registry for the 3 years prior to PTX. The incidence rate ratios (IRRs) of tooth loss by extraction, periodontal interventions, and dental visit rate were analyzed by Poisson regression models. In order to analyze the impact of disease severity, the PHPT cohort was sub-grouped based on preoperative serum levels of ionized calcium (S-Ca2+). The total number of tooth extractions, periodontal interventions, and number of visits were similar in the cohorts. PHPT patients belonging to the quartile with the highest S-Ca2+ (≥ 1.51 mmol/L) had increased risk for tooth extraction (IRR 1.85; 95% CI 1.39–2.46). Female gender independently amplified the risk (IRR 1.341, P < 0.027). This study indicates an association between pHPT and oral disorders reflected by increased tooth loss by extraction related to high S-Ca2. Increased awareness of dental comorbidity in primary hyperparathyroidism may benefit a large group of patients with a common disease through earlier detection and prevention.
Publication and Content Type
- ref (subject category)
- art (subject category)
Find in a library
- Clinical oral investigations (Search for host publication in LIBRIS)
To the university's database
- 1 of 1
- Previous record
- Next record
- To hitlist
Find more in SwePub
- By the author/editor
- Koman, A
- Nasman, P
- Discacciati, A
- Ekbom, A
- Nilsson, IL
- Sandborgh-Englun ...
- Articles in the publication
- Clinical oral in ...
- By the university
- Karolinska Institutet
Search outside SwePub
- Extend your search to:
- Google Book Search
- Google Scholar
Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.
- Copyright © LIBRIS - National Library Systems
- LIBRIS.kb.se
