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Butler enables rapi...
Butler enables rapid cloud-based analysis of thousands of human genomes
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- Yakneen, S (author)
- European Molecular Biology Laboratory Heidelberg
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- Waszak, SM (author)
- European Molecular Biology Laboratory Heidelberg
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- Gertz, M (author)
- Heidelberg University
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show more...
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- Korbel, JO (author)
- European Molecular Biology Laboratory Heidelberg
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Aminou, B (author)
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Bartolome, J (author)
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Boroevich, KA (author)
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Boyce, R (author)
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Brooks, AN (author)
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Buchanan, A (author)
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Buchhalter, I (author)
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Butler, AP (author)
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Byrne, NJ (author)
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Cafferkey, A (author)
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Campbell, PJ (author)
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Chen, ZH (author)
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Cho, S (author)
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Choi, W (author)
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Clapham, P (author)
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Davis-Dusenbery, BN (author)
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De La Vega, FM (author)
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Demeulemeester, J (author)
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Dow, MT (author)
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Dursi, LJ (author)
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Eils, J (author)
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Eils, R (author)
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Ellrott, K (author)
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Farcas, C (author)
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Favero, F (author)
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Fayzullaev, N (author)
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Ferretti, V (author)
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Flicek, P (author)
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Fonseca, NA (author)
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Gelpi, JL (author)
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Getz, G (author)
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Gibson, B (author)
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Grossman, RL (author)
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Harismendy, O (author)
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Heath, AP (author)
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Heinold, MC (author)
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Hess, JM (author)
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Hofmann, O (author)
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Hong, JH (author)
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Hudson, TJ (author)
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Hutter, B (author)
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Hutter, CM (author)
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Hubschmann, D (author)
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Imoto, S (author)
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Ivkovic, S (author)
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Jeon, SH (author)
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Jiao, W (author)
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Jung, J (author)
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Kabbe, R (author)
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Kahles, A (author)
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Kerssemakers, JNA (author)
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Kim, HL (author)
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Kim, H (author)
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Kim, J (author)
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Kim, Y (author)
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Kleinheinz, K (author)
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Koscher, M (author)
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Koures, A (author)
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Kovacevic, M (author)
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Lawerenz, C (author)
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Leshchiner, I (author)
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Liu, J (author)
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Livitz, D (author)
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Mihaiescu, GL (author)
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Mijalkovic, S (author)
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Lazic, AM (author)
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Miyano, S (author)
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Miyoshi, N (author)
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Nahal-Bose, HK (author)
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Nakagawa, H (author)
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Nastic, M (author)
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- Staaf, Johan (author)
- Lund University,Lunds universitet,Avdelningen för translationell cancerforskning,Institutionen för laboratoriemedicin,Medicinska fakulteten,Forskningsgrupp Lungcancer,Forskargrupper vid Lunds universitet,LUCC: Lunds universitets cancercentrum,Övriga starka forskningsmiljöer,Bröst/lungcancer,Sektion I,Institutionen för kliniska vetenskaper, Lund,Division of Translational Cancer Research,Department of Laboratory Medicine,Faculty of Medicine,Research Group Lung Cancer,Lund University Research Groups,LUCC: Lund University Cancer Centre,Other Strong Research Environments,Breast/lungcancer,Section I,Department of Clinical Sciences, Lund
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Nicholson, J (author)
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O'Connor, BD (author)
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Ocana, D (author)
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Ohi, K (author)
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Ohno-Machado, L (author)
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Omberg, L (author)
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Ouellette, BFF (author)
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Paramasivam, N (author)
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Perry, MD (author)
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Pihl, TD (author)
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Prinz, M (author)
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Puiggros, M (author)
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Radovic, P (author)
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Raine, KM (author)
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Rheinbay, E (author)
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Rosenberg, M (author)
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Royo, R (author)
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Ratsch, G (author)
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Saksena, G (author)
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Schlesner, M (author)
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Shorser, SI (author)
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Short, C (author)
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Sofia, HJ (author)
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Spring, J (author)
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Stein, LD (author)
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Struck, AJ (author)
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Tiao, G (author)
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Tijanic, N (author)
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Torrents, D (author)
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Van Loo, P (author)
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Vazquez, M (author)
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Vicente, D (author)
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Wala, JA (author)
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Wang, ZN (author)
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Weischenfeldt, J (author)
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Werner, J (author)
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Williams, A (author)
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Woo, Y (author)
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Wright, AJ (author)
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Xiang, Q (author)
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Yang, LM (author)
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Yuen, D (author)
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Yung, CK (author)
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Zhang, JJ (author)
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- Borg, Åke (creator_code:cre_t)
- Lund University,Lunds universitet,Bröstcancer-genetik,Sektion I,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Familjär bröstcancer,Forskargrupper vid Lunds universitet,LUCC: Lunds universitets cancercentrum,Övriga starka forskningsmiljöer,Breastcancer-genetics,Section I,Department of Clinical Sciences, Lund,Faculty of Medicine,Familial Breast Cancer,Lund University Research Groups,LUCC: Lund University Cancer Centre,Other Strong Research Environments
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- Ringnér, Markus (creator_code:cre_t)
- Lund University,Lunds universitet,Molekylär cellbiologi,Biologiska institutionen,Naturvetenskapliga fakulteten,Molecular Cell Biology,Department of Biology,Faculty of Science
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(creator_code:org_t)
- 2020-02-05
- 2020
- English.
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In: Nature biotechnology. - : Springer Science and Business Media LLC. - 1546-1696 .- 1087-0156. ; 38:3, s. 288-
- Related links:
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http://dx.doi.org/10... (free)
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Abstract
Subject headings
Close
- We present Butler, a computational tool that facilitates large-scale genomic analyses on public and academic clouds. Butler includes innovative anomaly detection and self-healing functions that improve the efficiency of data processing and analysis by 43% compared with current approaches. Butler enabled processing of a 725-terabyte cancer genome dataset from the Pan-Cancer Analysis of Whole Genomes (PCAWG) project in a time-efficient and uniform manner.
Subject headings
- NATURVETENSKAP -- Data- och informationsvetenskap -- Bioinformatik (hsv//swe)
- NATURAL SCIENCES -- Computer and Information Sciences -- Bioinformatics (hsv//eng)
Keyword
- Cloud Computing
- Computational Biology/methods
- Genome, Human
- Humans
- Neoplasms/genetics
- Software
Publication and Content Type
- ref (subject category)
- art (subject category)
Find in a library
To the university's database
- By the author/editor
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Yakneen, S
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Waszak, SM
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Gertz, M
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Korbel, JO
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Aminou, B
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Bartolome, J
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show more...
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Boroevich, KA
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Boyce, R
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Brooks, AN
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Buchanan, A
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Buchhalter, I
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Butler, AP
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Byrne, NJ
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Cafferkey, A
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Campbell, PJ
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Chen, ZH
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Cho, S
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Choi, W
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Clapham, P
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Davis-Dusenbery, ...
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De La Vega, FM
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Demeulemeester, ...
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Dow, MT
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Dursi, LJ
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Eils, J
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Eils, R
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Ellrott, K
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Farcas, C
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Favero, F
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Fayzullaev, N
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Ferretti, V
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Flicek, P
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Fonseca, NA
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Gelpi, JL
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Getz, G
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Gibson, B
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Grossman, RL
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Harismendy, O
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Heath, AP
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Heinold, MC
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Hess, JM
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Hofmann, O
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Hong, JH
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Hudson, TJ
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Hutter, B
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Hutter, CM
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Hubschmann, D
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Imoto, S
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Ivkovic, S
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Jeon, SH
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Jiao, W
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Jung, J
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Kabbe, R
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Kahles, A
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Kerssemakers, JN ...
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Kim, HL
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Kim, H
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Kim, J
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Kim, Y
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Kleinheinz, K
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Koscher, M
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Koures, A
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Kovacevic, M
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Lawerenz, C
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Leshchiner, I
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Liu, J
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Livitz, D
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Mihaiescu, GL
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Mijalkovic, S
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Lazic, AM
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Miyano, S
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Miyoshi, N
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Nahal-Bose, HK
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Nakagawa, H
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Nastic, M
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Staaf, Johan
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Nicholson, J
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O'Connor, BD
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Ocana, D
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Ohi, K
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Ohno-Machado, L
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Omberg, L
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Ouellette, BFF
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Paramasivam, N
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Perry, MD
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Pihl, TD
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Prinz, M
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Puiggros, M
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Radovic, P
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Raine, KM
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Rheinbay, E
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Rosenberg, M
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Royo, R
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Ratsch, G
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Saksena, G
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Schlesner, M
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Shorser, SI
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Short, C
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Sofia, HJ
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Spring, J
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Stein, LD
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Struck, AJ
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Tiao, G
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Tijanic, N
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Torrents, D
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Van Loo, P
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Vazquez, M
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Vicente, D
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Wala, JA
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Wang, ZN
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Weischenfeldt, J
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Werner, J
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Williams, A
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Woo, Y
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Wright, AJ
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Xiang, Q
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Yang, LM
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Yuen, D
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Yung, CK
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Zhang, JJ
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Borg, Åke
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Ringnér, Markus
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show less...
- About the subject
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- NATURAL SCIENCES
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NATURAL SCIENCES
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and Computer and Inf ...
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and Bioinformatics
- Articles in the publication
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Nature biotechno ...
- By the university
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Karolinska Institutet
-
Lund University