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Fluorescent SAM analogues for methyltransferase based DNA labeling
- Goyvaerts, V (author)
- Van Snick, S (author)
- D'Huys, L (author)
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- Vitale, R (author)
- Lauer, MH (author)
- Wang, S (author)
- Leen, V (author)
- Dehaen, W (author)
- Hofkens, J (author)
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- 2020
- 2020
- English.
- In: Chemical communications (Cambridge, England). - : Royal Society of Chemistry (RSC). - 1364-548X .- 1359-7345. ; 56:22, s. 3317-3320
- Journal article (peer-reviewed)
Abstract
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- In this work, the preparation of new S-adenosyl-l-methionine (SAM) analogues for sequence specific DNA labeling is evaluated. Fluorescent cofactors were synthesized and their applicability in methyltransferase based optical mapping is demonstrated.
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- Goyvaerts, V
- Van Snick, S
- D'Huys, L
- Vitale, R
- Lauer, MH
- Wang, S
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- Leen, V
- Dehaen, W
- Hofkens, J
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- Karolinska Institutet
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