id:"swepub:oai:prod.swepub.kib.ki.se:1961374"
Search: id:"swepub:oai:prod.swepub.kib.ki.se:1961374" > beta-Receptor respo...
- 1 of 1
- Previous record
- Next record
- To hitlist
beta-Receptor response to noradrenaline in cluster headache. A study of adipose tissue lipolysis
- Meyer, EL (author)
-
- Waldenlind, E (author)
- Karolinska Institutet
-
- Marcus, C (author)
- Karolinska Institutet
- (creator_code:org_t)
- 2016-11-25
- 2006
- English.
- In: Cephalalgia : an international journal of headache. - : SAGE Publications. - 0333-1024. ; 26:7, s. 831-836
- Journal article (peer-reviewed)
Abstract
Subject headings
Close
- We have previously shown decreased lipolysis in both phases of cluster headache (CH), as an indication of a sympathetic dysregulation. Reduced lipolysis could be a result of diminished β-receptor sensitivity in adipose tissue. The aim of this study was to measure the lipolytic response to noradrenaline in 10 CH patients in remission and in 10 healthy subjects, to estimate β-receptor function. Microdialysis technique was used to measure the increase of glycerol, the end-product of lipolysis, during infusion of noradrenaline into the adipose tissue. Noradrenaline infusion resulted in a distinct elevation of glycerol. The average glycerol increase was significantly higher in CH patients (121± ± 48) than in healthy subjects (77± ± 41) ( P < 0.05), which indicates increased β-receptor response to noradrenaline in CH patients in remission. This may be due to up-regulated β-receptor sensitivity, secondary to reduced sympathetic outflow and a primary autonomic disturbance in CH.
Publication and Content Type
- ref (subject category)
- art (subject category)
Find in a library
- Cephalalgia : an international journal of headache (Search for host publication in LIBRIS)
To the university's database
- 1 of 1
- Previous record
- Next record
- To hitlist
Find more in SwePub
- By the author/editor
- Meyer, EL
- Waldenlind, E
- Marcus, C
- Articles in the publication
- Cephalalgia : an ...
- Cephalalgia
- By the university
- Karolinska Institutet
Search outside SwePub
- Extend your search to:
- Google Book Search
- Google Scholar
Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.
- Copyright © LIBRIS - National Library Systems
- LIBRIS.kb.se
