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Motor unit characte...
Motor unit characteristics after selective nerve transfers
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- Bergmeister, Konstantin Davide (författare)
- Medizinische Universität Wien,Medical University of Vienna
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- Aman, Martin (författare)
- Medizinische Universität Wien,Medical University of Vienna
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- Sporer, Matthias (författare)
- Medizinische Universität Wien,Medical University of Vienna
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- Willensdorfer, Anna (författare)
- Medizinische Universität Wien,Medical University of Vienna
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- Muceli, Silvia, 1981 (författare)
- Chalmers tekniska högskola,Chalmers University of Technology
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- Vujaklija, Ivan (författare)
- Aalto-Yliopisto,Aalto University
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- Aszmann, Oskar C. (författare)
- Medizinische Universität Wien,Medical University of Vienna
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- Farina, Dario (författare)
- Imperial College of Science, Technology and Medicine
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(creator_code:org_t)
- 2021-01-05
- 2021
- Engelska.
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Ingår i: Bionic Limb Reconstruction. - Cham : Springer International Publishing. ; , s. 83-91
- Relaterad länk:
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https://doi.org/10.1...
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https://research.cha...
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Abstract
Ämnesord
Stäng
- Selective nerve transfers are used in biological and bionic extremity reconstruction to restore and improve extremity function. Here, peripheral nerves are rerouted to various target muscles, and thereby the structural composition of motor units is surgically altered. Previous studies have shown a high success rate of successful reinnervation of above 90% after these nerve transfers. In targeted muscle reinnervation, nerve transfers are applied to reroute amputated nerves to more proximal muscles in the stump and thereby increase the number of prosthetic control signals. Because donor nerves physiologically supply multiple muscles but are transferred to a single target muscle, the innervation ratio between donor and recipient is substantially altered. This changes the characteristics of the motor unit of the target muscles that we extensively investigated in a novel nerve transfer animal model. In this chapter, we illustrate this model, the effect of nerve transfers on motor unit physiology, as well as the implications on improving the interface between man and machine in prosthetic extremity reconstruction. In addition, first results on the effect of targeted muscle reinnervation on human motor unit physiology are described.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Neurovetenskaper (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Neurosciences (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Fysiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Physiology (hsv//eng)
- NATURVETENSKAP -- Data- och informationsvetenskap -- Bioinformatik (hsv//swe)
- NATURAL SCIENCES -- Computer and Information Sciences -- Bioinformatics (hsv//eng)
Nyckelord
- Nerve transfer
- Hyper-reinnervation
- TMR
- Targeted muscle reinnervation
- Motor unit
Publikations- och innehållstyp
- kap (ämneskategori)
- vet (ämneskategori)
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