Hyperbaric Oxygen Acutely Increases Wound Circulation as Assessed by Fluorescent Angiography

• The efficacy of hyperbaric oxygen therapy (HBOT) to facilitate wound healing in diabetic lower extremity ulcers is well established. The exact mechanism of HBOT-mediated wound healing is unclear but is thought to relate to increased reactive oxygen species and reactive nitrogen species (ROS and RNS). ROS and RNS lead to many downstream affects that impact wound healing, including increased growth factors, diminished inflammatory responses, and improved neovascularization. The impact of HBOT, however, on tissue perfusion and flow is not known. The purpose of this pilot study was to ascertain the immediate effects of HBOT on the microvasculature of chronic wounds as assessed by fluorescent angiography.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Kirurgi (hsv//swe)

MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Surgery (hsv//eng)

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Kardiologi (hsv//swe)

MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Radiologi och bildbehandling (hsv//swe)

MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Radiology, Nuclear Medicine and Medical Imaging (hsv//eng)

Keyword

Diabetic foot ulcer

Angiography

Hyperbaric oxygene treatment

Publication and Content Type

kon (subject category)

vet (subject category)