Search: id:"swepub:oai:research.chalmers.se:f6e3ad5d-5916-4074-95e9-c90ca7acfe0b" >
A biohybrid dynamic...
A biohybrid dynamic random access memory
-
- Sinclair, J. (author)
- Chalmers tekniska högskola,Chalmers University of Technology
-
- Granfeldt, D. (author)
- Chalmers tekniska högskola,Chalmers University of Technology
-
Pihl, Johan, 1975 (author)
-
show more...
-
- Millingen, Maria, 1980 (author)
- Chalmers tekniska högskola,Chalmers University of Technology
-
- Lincoln, Per, 1958 (author)
- Chalmers tekniska högskola,Chalmers University of Technology
-
Farre, C. (author)
-
- Peterson, Lena, 1961 (author)
- Chalmers tekniska högskola,Chalmers University of Technology
-
- Orwar, Owe, 1964 (author)
- Chalmers tekniska högskola,Chalmers University of Technology
-
show less...
-
(creator_code:org_t)
- 2006-03-24
- 2006
- English.
-
In: Journal of the American Chemical Society. - : American Chemical Society (ACS). - 1520-5126 .- 0002-7863. ; 128:15, s. 5109-5113
- Related links:
-
https://research.cha...
-
show more...
-
https://doi.org/10.1...
-
show less...
Abstract
Subject headings
Close
- We report that GABA(A) receptors in a patch-clamped biological cell form a short-term memory circuit when integrated with a scanning-probe microfluidic device. Laminar patterns of receptor activators (agonists) provided by the microfluidic device define and periodically update the data input which is read and stored by the receptors as state distributions (based on intrinsic multistate kinetics). The memory is discharged over time and lasts for seconds to minutes depending on the input function. The function of the memory can be represented by an equivalent electronic circuit with striking similarity in function to a dynamic random access memory (DRAM) used in electronic computers. Multiplexed biohybrid memories may form the basis of large-scale integrated biocomputational/sensor devices with the curious ability to use chemical signals including odorants, neurotransmitters, chemical and biological warfare agents, and many more as input signals.
Subject headings
- NATURVETENSKAP -- Kemi (hsv//swe)
- NATURAL SCIENCES -- Chemical Sciences (hsv//eng)
Publication and Content Type
- art (subject category)
- ref (subject category)
Find in a library
To the university's database
- By the author/editor
-
Sinclair, J.
-
Granfeldt, D.
-
Pihl, Johan, 197 ...
-
Millingen, Maria ...
-
Lincoln, Per, 19 ...
-
Farre, C.
-
show more...
-
Peterson, Lena, ...
-
Orwar, Owe, 1964
-
show less...
- About the subject
-
- NATURAL SCIENCES
-
NATURAL SCIENCES
-
and Chemical Science ...
- Articles in the publication
-
Journal of the A ...
- By the university
-
Chalmers University of Technology