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Recent advances in genomics of equine health, welfare and performance
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- Mikko, Sofia (author)
- Swedish University of Agricultural Sciences,Sveriges lantbruksuniversitet,Institutionen för husdjursgenetik (HGEN),Department of Animal Breeding and Genetics
- (creator_code:org_t)
- ISBN 9789086869404
- 2023-02-09
- 2022
- English.
- Conference paper (peer-reviewed)
Abstract
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- Equine research and breeding have encountered major changes due to the rapid development of molecular genetic technology. Today, there are 254 equine traits listed in Online Mendelian Inheritance in Animals (OMIA), while the HorseQTLdb lists 2,605 QTLs representing 64 traits. Strong selection increases the risk of inbreeding and multiplication of deleterious variants. Analysis of genomic regions under selection, and trio sequencing could complement Genome-wide Association Studies (GWAS) in the search for genetic background of traits and diseases. The increased possibilities to test for a variety of disease-causing mutations, or performance-associated QTLs, support breeders in informed breeding decisions. SNP genotyping will most likely be implemented for horse parentage analysis in the near future. This large amount of genomic data will open new possibilities to address research questions, and will make it possible to carry out marker-assisted and/or genomic selection also in horses.
Subject headings
- LANTBRUKSVETENSKAPER -- Bioteknologi med applikationer på växter och djur -- Genetik och förädling inom lantbruksvetenskap (hsv//swe)
- AGRICULTURAL SCIENCES -- Agricultural Biotechnology -- Genetics and Breeding in Agricultural Sciences (hsv//eng)
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