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Sökning: onr:"swepub:oai:DiVA.org:hb-1985" > Mechanical chest co...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00005948naa a2200625 4500
001oai:DiVA.org:hb-1985
003SwePub
008151113s2014 | |||||||||||000 ||eng|
009oai:DiVA.org:hb-1663
009oai:DiVA.org:uu-216731
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:hb:diva-19852 URI
0247 a https://doi.org/10.1001/jama.2013.2825382 DOI
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:hb:diva-16632 URI
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-2167312 URI
040 a (SwePub)hbd (SwePub)uu
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
1001 a Rubertsson, Stenu Uppsala universitet,Anestesiologi och intensivvård4 aut0 (Swepub:uu)stenrube
2451 0a Mechanical chest compressions and simultanous defibrillationvs conventional cardiopulmonary resuscitationin out-of hospital cardiac arrest:the LINC randomized trial
264 1b American Medical Association,c 2014
338 a print2 rdacarrier
520 a IMPORTANCE: A strategy using mechanical chest compressions might improve the poor outcome in out-of-hospital cardiac arrest, but such a strategy has not been tested in large clinical trials. OBJECTIVE: To determine whether administering mechanical chest compressions with defibrillation during ongoing compressions (mechanical CPR), compared with manual cardiopulmonary resuscitation (manual CPR), according to guidelines, would improve 4-hour survival. DESIGN, SETTING, AND PARTICIPANTS: Multicenter randomized clinical trial of 2589 patients with out-of-hospital cardiac arrest conducted between January 2008 and February 2013 in 4 Swedish, 1 British, and 1 Dutch ambulance services and their referring hospitals. Duration of follow-up was 6 months. INTERVENTIONS: Patients were randomized to receive either mechanical chest compressions (LUCAS Chest Compression System, Physio-Control/Jolife AB) combined with defibrillation during ongoing compressions (n = 1300) or to manual CPR according to guidelines (n = 1289). MAIN OUTCOMES AND MEASURES: Four-hour survival, with secondary end points of survival up to 6 months with good neurological outcome using the Cerebral Performance Category (CPC) score. A CPC score of 1 or 2 was classified as a good outcome. RESULTS: Four-hour survival was achieved in 307 patients (23.6%) with mechanical CPR and 305 (23.7%) with manual CPR (risk difference, -0.05%; 95% CI, -3.3% to 3.2%; P > .99). Survival with a CPC score of 1 or 2 occurred in 98 (7.5%) vs 82 (6.4%) (risk difference, 1.18%; 95% CI, -0.78% to 3.1%) at intensive care unit discharge, in 108 (8.3%) vs 100 (7.8%) (risk difference, 0.55%; 95% CI, -1.5% to 2.6%) at hospital discharge, in 105 (8.1%) vs 94 (7.3%) (risk difference, 0.78%; 95% CI, -1.3% to 2.8%) at 1 month, and in 110 (8.5%) vs 98 (7.6%) (risk difference, 0.86%; 95% CI, -1.2% to 3.0%) at 6 months with mechanical CPR and manual CPR, respectively. Among patients surviving at 6 months, 99% in the mechanical CPR group and 94% in the manual CPR group had CPC scores of 1 or 2. CONCLUSIONS AND RELEVANCE: Among adults with out-of-hospital cardiac arrest, there was no significant difference in 4-hour survival between patients treated with the mechanical CPR algorithm or those treated with guideline-adherent manual CPR. The vast majority of survivors in both groups had good neurological outcomes by 6 months. In clinical practice, mechanical CPR using the presented algorithm did not result in improved effectiveness compared with manual CPR. TRIAL REGISTRATION: clinicaltrials.gov Identifier: NCT00609778.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Hälsovetenskapx Omvårdnad0 (SwePub)303052 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Health Sciencesx Nursing0 (SwePub)303052 hsv//eng
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Kardiologi0 (SwePub)302062 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cardiac and Cardiovascular Systems0 (SwePub)302062 hsv//eng
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Dermatologi och venereologi0 (SwePub)302042 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Dermatology and Venereal Diseases0 (SwePub)302042 hsv//eng
653 a Prehospital akutsjukvård
653 a Integrated Caring Science
653 a Integrerad vårdutveckling
7001 a Lindgren, Eriku Uppsala universitet,Anestesiologi och intensivvård4 aut0 (Swepub:uu)erili635
7001 a Smekal, Davidu Uppsala universitet,Anestesiologi och intensivvård4 aut0 (Swepub:uu)davsm531
7001 a Östlund, Ollieu Uppsala universitet,Uppsala kliniska forskningscentrum (UCR)4 aut0 (Swepub:uu)oos27600
7001 a Silverstolpe, Johan4 aut
7001 a Lichtveld, Robert A4 aut
7001 a Boomars, Rene4 aut
7001 a Ahlstedt, Björn4 aut
7001 a Skoog, Gunnar4 aut
7001 a Kastberg, Robert4 aut
7001 a Halliwell, David4 aut
7001 a Box, Martyn4 aut
7001 a Herlitz, Johanu Högskolan i Borås,Institutionen för Vårdvetenskap,Prehospital akutsjukvård4 aut0 (Swepub:hb)jhz
7001 a Karlsten, Rolfu Uppsala universitet,Anestesiologi och intensivvård4 aut0 (Swepub:uu)rolfkarl
7001 a Smekal, E4 aut
7001 a Skoog, B4 aut
7102 a Uppsala universitetb Anestesiologi och intensivvård4 org
7730 t Journal of the American Medical Association (JAMA)d : American Medical Associationg 311:1, s. 53-61q 311:1<53-61x 0098-7484x 1538-3598
8564 u https://jamanetwork.com/journals/jama/articlepdf/1774037/joi130105.pdf
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:hb:diva-1985
8564 8u https://doi.org/10.1001/jama.2013.282538
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:hb:diva-1663
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-216731

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