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Sökning: onr:"swepub:oai:DiVA.org:his-19650" > Improving cardiores...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00008789naa a2200601 4500
001oai:DiVA.org:his-19650
003SwePub
008210422s2022 | |||||||||||000 ||eng|
009oai:gup.ub.gu.se/303337
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:his:diva-196502 URI
0247 a https://doi.org/10.1038/s41390-021-01471-02 DOI
0247 a https://gup.ub.gu.se/publication/3033372 URI
040 a (SwePub)hisd (SwePub)gu
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
1001 a González-Gil, Esther M.u Department of Biochemistry and Molecular Biology II, Instituto de Nutrición y Tecnología de los Alimentos, Center of Biomedical Research (CIBM), Universidad de Granada, Spain ; GENUD (Growth, Exercise, Nutrition and Development) Research Group, University of Zaragoza, Spain ; Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y Nutrición (CIBERObn), Instituto de Salud Carlos III, Madrid, Spain4 aut
2451 0a Improving cardiorespiratory fitness protects against inflammation in children :b the IDEFICS study
264 c 2021-04-09
264 1b Springer Nature,c 2022
338 a print2 rdacarrier
500 a © 2021, The Author(s), under exclusive licence to the International Pediatric Research Foundation, Inc.Published online: 9 April 2021
520 a Background: Muscular and cardiorespiratory fitness (MF and CRF) have been related to inflammation. Thus, the aim of this study was to assess the relationship between fitness and high-sensitivity C-reactive protein (hs-CRP) in European children both in the cross-sectional and longitudinal analysis. Methods: Three hundred and fifty-seven children (46.2% males) aged 2–9 years with hs-CRP measured, data from MF and CRF, diet quality, objectively measured physical activity (PA) and screen time at baseline and follow-up after 2 years were included. Body mass index z-score (zBMI), waist circumference (WC) and fat mass index (FMI) were assessed. MF and CRF were also dichotomized as follows: low-medium quartiles (Q1–Q3) and highest quartile (Q4). Results: At follow-up, children with the highest CRF (Q4) showed a lower probability of having high hs-CRP. In the longitudinal analysis, children who improved their CRF over time showed a significantly lower probability (p < 0.05) of being in the highest hs-CRP category at follow-up, independently of the body composition index considered: odds ratio (OR) = 0.22 for zBMI, OR = 0.17 for WC, and OR = 0.21 for FMI. Conclusions: Improving CRF during childhood reduces the odds of an inflammatory profile, independently of body composition and lifestyle behaviours. These highlight the importance of enhancing fitness, especially CRF, to avoid an inflammatory state in children. Impact: Improvements in the cardiorespiratory profile during childhood could reverse an unfavourable inflammatory status.There is a longitudinal and inverse association between CRF and inflammation in children.This is the first longitudinal study assessing the relationship between fitness and inflammation during childhood that takes also into account the lifestyle behaviours.Results from the present study suggest a protective role of fitness already in childhood.Efforts to improve fitness in children should be aimed at as inflammation could trigger future cardiovascular disease. 
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Kardiologi0 (SwePub)302062 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cardiac and Cardiovascular Systems0 (SwePub)302062 hsv//eng
650 7a MEDICIN OCH HÄLSOVETENSKAPx Hälsovetenskapx Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi0 (SwePub)303022 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Health Sciencesx Public Health, Global Health, Social Medicine and Epidemiology0 (SwePub)303022 hsv//eng
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Pediatrik0 (SwePub)302212 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Pediatrics0 (SwePub)302212 hsv//eng
653 a Research on Citizen Centered Health, University of Skövde (Reacch US)
653 a Medborgarcentrerad hälsa (Mech)
7001 a Santaliestra-Pasías, Alba M.u GENUD (Growth, Exercise, Nutrition and Development) Research Group, University of Zaragoza, Zaragoza, Spain ; Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y Nutrición (CIBERObn), Instituto de Salud Carlos III, Madrid, Spain ; Instituto Agroalimentario de Aragón (IA2), Zaragoza, Spain ; Instituto de Investigación Sanitaria Aragón (IIS Aragón), Zaragoza, Spain4 aut
7001 a Buck, Christophu Leibniz Institute for Prevention Research and Epidemiology—BIPS, Bremen, Germany4 aut
7001 a Gracia-Marco, Luisu GENUD (Growth, Exercise, Nutrition and Development) Research Group, University of Zaragoza, Zaragoza, Spain ; PROFITH (PROmoting FITness and Health through physical activity) Research Group, Department of Physical Education and Sports, Faculty of Sport Sciences, Sport and Health University Research Institute (iMUDS), University of Granada, Spain4 aut
7001 a Lauria, Fabiou Institute of Food Sciences, National Research Council, Avellino, Italy4 aut
7001 a Pala, Valeriau Epidemiology and Prevention Unit, Fondazione IRCCS—Istituto Nazionale dei Tumori, Milan, Italy4 aut
7001 a Molnar, Denesu Department of Pediatrics, Medical School, University of Pécs, Hungary4 aut
7001 a Veidebaum, Toomasu National Institute for Health Development, Center of Health and Behavioral Science, Tallinn, Estonia4 aut
7001 a Iacoviello, Liciau Department of Epidemiology and Prevention, IRCCS Istituto Neurologico Mediterraneo Neuromed, Pozzilli, Italy ; Department of Medicine and Surgery, Research Center in Epidemiology and Preventive Medicine (EPIMED), University of Insubria, Varese, Italy4 aut
7001 a Tornaritis, Michaelu Research and Education Institute of Child Health, Strovolos, Cyprus4 aut
7001 a Eiben, Gabrieleu Högskolan i Skövde,Institutionen för hälsovetenskaper,Forskningsmiljön hälsa, hållbarhet och digitalisering,Medborgarcentrerad hälsa MeCH, Research on Citizen Centered Health, University of Skövde (Reacch US)4 aut0 (Swepub:his)eibg
7001 a Lissner, Lauren,d 1956u Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa,Institute of Medicine, School of Public Health and Community Medicine4 aut0 (Swepub:gu)xlisla
7001 a Schwarz, Heikeu Leibniz Institute for Prevention Research and Epidemiology—BIPS, Bremen, Germany4 aut
7001 a Ahrens, Wolfgangu Leibniz Institute for Prevention Research and Epidemiology—BIPS, Bremen, Germany ; Institute of Statistics, Bremen University, Germany4 aut
7001 a De Henauw, Stefaanu Department of Public Health and Primary Care, Faculty of Medicine and Health Sciences, Ghent University, Belgium4 aut
7001 a Fraterman, Arnou Laboratoriumsmedizin Dortmund, Eberhard & Partner, Dortmund, Germany4 aut
7001 a Moreno, Luis A.u GENUD (Growth, Exercise, Nutrition and Development) Research Group, University of Zaragoza, Zaragoza, Spain ; Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y Nutrición (CIBERObn), Instituto de Salud Carlos III, Madrid, Spain ; Instituto Agroalimentario de Aragón (IA2), Zaragoza, Spain ; Instituto de Investigación Sanitaria Aragón (IIS Aragón), Zaragoza, Spain4 aut
7102 a Department of Biochemistry and Molecular Biology II, Instituto de Nutrición y Tecnología de los Alimentos, Center of Biomedical Research (CIBM), Universidad de Granada, Spain ; GENUD (Growth, Exercise, Nutrition and Development) Research Group, University of Zaragoza, Spain ; Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y Nutrición (CIBERObn), Instituto de Salud Carlos III, Madrid, Spainb GENUD (Growth, Exercise, Nutrition and Development) Research Group, University of Zaragoza, Zaragoza, Spain ; Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y Nutrición (CIBERObn), Instituto de Salud Carlos III, Madrid, Spain ; Instituto Agroalimentario de Aragón (IA2), Zaragoza, Spain ; Instituto de Investigación Sanitaria Aragón (IIS Aragón), Zaragoza, Spain4 org
7730 t Pediatric Researchd : Springer Natureg 91:3, s. 681-689q 91:3<681-689x 0031-3998x 1530-0447
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:his:diva-19650
8564 8u https://doi.org/10.1038/s41390-021-01471-0
8564 8u https://gup.ub.gu.se/publication/303337

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