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Sökning: onr:"swepub:oai:DiVA.org:kth-284910" > Biocompliant Compos...
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| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 03847naa a2200697 4500 | |
| 001 | oai:DiVA.org:kth-284910 | |
| 003 | SwePub | |
| 008 | 201209s2020 | |||||||||||000 ||eng| | |
| 024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-2849102 URI |
| 024 | 7 | a https://doi.org/10.1002/adhm.2020010402 DOI |
| 040 | a (SwePub)kth | |
| 041 | a engb eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a ref2 swepub-contenttype |
| 072 | 7 | a art2 swepub-publicationtype |
| 100 | 1 | a Lehman, S E4 aut |
| 245 | 1 0 | a Biocompliant Composite Au/pHEMA Plasmonic Scaffolds for 3D Cell Culture and Noninvasive Sensing of Cellular Metabolites |
| 264 | c 2020-09-09 | |
| 264 | 1 | b Wiley-VCH Verlag,c 2020 |
| 338 | a print2 rdacarrier | |
| 500 | a QC 20201209In press | |
| 520 | a The field of 3D printing is an area of active research, with a substantial focus given to the design and construction of customized tools for applications in technology. There exists a particular need in these developing areas of opportunity for new multi-functional soft materials that are biologically compatible for the growth and directed culturing of cells. Herein, a composite material consisting of gold nanoparticles with useful plasmonic properties embedded within a highly hydrophilic poly-2-hydroxyethylmethacrylate matrix is described and characterized. This composite material serves dual functions as both host framework scaffold for cell lines such as pre-osteoblasts as well as a plasmonic biosensor for in situ measurements of living cells. The plasmonic properties of this system are characterized as a function of the material properties and related to compositional features of the material through a proposed light-directed mechanism. This chemistry provides a tunable, 3D printable plasmonic composite material of encapsulated gold nanoparticles in a biologically-compliant, acrylate-based hydrogel matrix. Surface-enhanced Raman scattering studies of 3D-microcultures supported by the scaffolds are carried out and the strong influence of perm-selective molecular diffusion in its analytical responses is established. Most notably, specific, largely hydrophilic, cellular metabolites are detected within the supported live cultures. | |
| 650 | 7 | a NATURVETENSKAPx Fysikx Den kondenserade materiens fysik0 (SwePub)103042 hsv//swe |
| 650 | 7 | a NATURAL SCIENCESx Physical Sciencesx Condensed Matter Physics0 (SwePub)103042 hsv//eng |
| 653 | a 3D printers | |
| 653 | a 3D printing | |
| 653 | a Cell culture | |
| 653 | a Cells | |
| 653 | a Cellular metabolites | |
| 653 | a Composite materials | |
| 653 | a Compositional features | |
| 653 | a Design and construction | |
| 653 | a Fiber optic sensors | |
| 653 | a Gold nanoparticles | |
| 653 | a Hydrophilicity | |
| 653 | a Hydroxyethylmethacrylate | |
| 653 | a Metabolites | |
| 653 | a Metal nanoparticles | |
| 653 | a Non-invasive sensing | |
| 653 | a Plasmonic biosensors | |
| 653 | a Plasmonic nanoparticles | |
| 653 | a Plasmonic properties | |
| 653 | a Plasmonics | |
| 653 | a Raman scattering | |
| 653 | a SERS | |
| 653 | a Scaffolds (biology) | |
| 653 | a Soft materials | |
| 653 | a Surface enhanced Raman Scattering (SERS) | |
| 653 | a Surface scattering | |
| 653 | a bio-compliant | |
| 653 | a biomimetics | |
| 653 | a gels | |
| 653 | a plasmonic sensing | |
| 700 | 1 | a McCracken, J M4 aut |
| 700 | 1 | a Miller, L A4 aut |
| 700 | 1 | a Jayalath, S4 aut |
| 700 | 1 | a Nuzzo, Ralph G.u KTH,Yt- och korrosionsvetenskap4 aut0 (Swepub:kth)u14f4mg7 |
| 710 | 2 | a KTHb Yt- och korrosionsvetenskap4 org |
| 773 | 0 | t Advanced Healthcare Materialsd : Wiley-VCH Verlagx 2192-2640x 2192-2659 |
| 856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-284910 |
| 856 | 4 8 | u https://doi.org/10.1002/adhm.202001040 |
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- Lehman, S E
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