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LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00002996naa a2200349 4500
001oai:DiVA.org:liu-101422
003SwePub
008131122s2005 | |||||||||||000 ||eng|
024a https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-1014222 URI
024a https://doi.org/10.1016/j.surg.2005.09.0202 DOI
040 a (SwePub)liu
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
100a Lorenz, Kerstinu Martin-Luther University of Halle-Wittenberg, Germany4 aut
2451 0a Selective arterial chemoembolization for hepatic metastases from medullary thyroid carcinoma
264 1b Elsevier,c 2005
338 a print2 rdacarrier
500 a Discussion page 993
520 a BACKGROUND: Hepatic metastases from medullary thyroid carcinoma (MTC) may impair quality of life by hypercalcitonemia-associated diarrhea and pain. In this prospective study, the effect of selective arterial chemoembolization (SACE) was evaluated.METHODS: Eleven patients with hepatic metastases from MTC received 1 to 9 courses of SACE using epirubicine. Symptomatic, biochemical, and morphologic responses on SACE were recorded.RESULTS: Symptomatic response was observed in all symptomatic patients. However, biochemical and radiologic response occurred only in 6 patients. Liver function was not affected by SACE. One patient with unexpected concurrent pheochromocytoma metastases died after the first course. Development of side effects in the course was observed in 8 patients but were only World Health Organization grade 1. Patients' satisfaction with SACE was excellent. Long-term follow-up found 7 patients alive (1-72 months). Three patients died with tumor 6, 12, and 24 months after SACE, respectively.CONCLUSION: SACE provided good symptom palliation for the majority of patients with hepatic metastases from MTC. However, transient remission or stabilization of hepatic metastases resulted in only 60%. Further studies using a randomized protocol are required.
700a Brauckhoff, Michaelu Martin-Luther University of Halle-Wittenberg, Germany4 aut
700a Behrmann, Curdu Martin-Luther University of Halle-Wittenberg, Germany4 aut
700a Sekulla, Carstenu Martin-Luther University of Halle-Wittenberg, Germany4 aut
700a Ukkat, Jörgu Martin-Luther University of Halle-Wittenberg, Germany4 aut
700a Brauckhoff, Katrinu Martin-Luther University of Halle-Wittenberg, Germany4 aut
700a Gimm, Oliveru Martin-Luther University of Halle-Wittenberg, Germany4 aut0 (Swepub:liu)oligi51
700a Dralle, Henningu Martin-Luther University of Halle-Wittenberg, Germany4 aut
710a Martin-Luther University of Halle-Wittenberg, Germany4 org
773t Surgeryd : Elsevierg 138:6, s. 986-993q 138:6<986-993x 0039-6060x 1532-7361
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-101422
8564 8u https://doi.org/10.1016/j.surg.2005.09.020

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