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Sökning: onr:"swepub:oai:DiVA.org:liu-167734" > Risk factors for pe...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00004639naa a2200529 4500
001oai:DiVA.org:liu-167734
003SwePub
008200721s2020 | |||||||||||000 ||eng|
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-1677342 URI
0247 a https://doi.org/10.1007/s00380-020-01653-62 DOI
040 a (SwePub)liu
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
1001 a Droppa, Michalu Univ Hosp Tubingen, Germany4 aut
2451 0a Risk factors for permanent pacemaker implantation in patients receiving a balloon-expandable transcatheter aortic valve prosthesis
264 c 2020-06-26
264 1b Springer,c 2020
338 a print2 rdacarrier
500 a Funding Agencies|Edwards Lifesciences (Nyon, Switzerland)
520 a Permanent pacemaker implantation (PPI) is a widely recognized complication associated with TAVI (incidence up to 20%). Smaller registries have identified several variables associated with PPI. The objective was to validate patient- and transcatheter aortic valve implantation (TAVI)-related procedural variables associated with PPI. We performed a retrospective analysis of patients from six European centers undergoing TAVI with the Edwards SAPIEN 3 prosthesis. Baseline variables and pre-procedural ECG characteristics and CT-scans were taken into account. Data for 1745 patients were collected; 191 (10.9%) required PPI after TAVI. The baseline variables pulmonary hypertension (OR 1.64; 95% CI 1.01-2.59), QRS duration > 117 ms (OR 2.58; 95% CI 1.73-3.84), right bundle branch block (RBBB; OR 5.14; 95% CI 3.39-7.72), left anterior hemi block (OR 1.92; 95% CI 1.19-3.02) and first-degree atrioventricular block (AVB, OR 1.63; 95%CI 1.05-2.46) were significantly associated with PPI. RBBB (OR 8.11; 95% CI 3.19-21.86) and first-degree AVB (OR 2.39; 95% CI 1.18-4.66) remained significantly associated in a multivariate analysis. Procedure-related variables included access site (TF; OR 1.97; 95% CI 1.07-4.05), implanted valve size (29 mm; OR 1.88; 95% CI 1.35-2.59), mean TAVI valve implantation depth below the annulus > 30% (OR 3.75; 95% CI 2.01-6.98). Patients receiving PPI had longer ICU stays and later discharges. Acute kidney injury stage 2/3 was more common in patients with PPI until discharge (15.2 vs. 3.1%;p = 0.007), but was not statistically significant thereafter. Further differences in outcomes at 30 days did not reach significance. The data will aid pre- and post-procedural patient management and prevent adverse long-term outcomes. Clinical Trial: NCT03497611.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Kirurgi0 (SwePub)302122 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Surgery0 (SwePub)302122 hsv//eng
653 a Aortic stenosis; Transcatheter aortic valve implantation; Pacemaker
7001 a Rudolph, Tanja K.u Cologne Univ, Germany; Heart and Diabet Ctr NRW, Germany4 aut
7001 a Baan, Janu Univ Amsterdam, Netherlands4 aut
7001 a Nielsen, Niels Erik,d 1956-u Linköpings universitet,Avdelningen för diagnostik och specialistmedicin,Medicinska fakulteten,Region Östergötland, Kardiologiska kliniken US4 aut0 (Swepub:liu)nieni36
7001 a Baumgartner, Helmutu Univ Hosp Muenster, Germany4 aut
7001 a Vendrik, Jeroenu Univ Amsterdam, Netherlands4 aut
7001 a Froehlich, Marenu Inst Pharmacol and Prevent Med, Germany4 aut
7001 a Borst, Oliveru Univ Hosp Tubingen, Germany4 aut
7001 a Woehrle, Jochenu Univ Ulm, Germany4 aut
7001 a Gawaz, Meinradu Univ Hosp Tubingen, Germany4 aut
7001 a Potratz, Paulu Univ Hosp Tubingen, Germany4 aut
7001 a Hack, Luis P.u Univ Hosp Tubingen, Germany4 aut
7001 a Mauri, Victoru Cologne Univ, Germany4 aut
7001 a Baranowski, Jaceku Region Östergötland, Kardiologiska kliniken US4 aut0 (Swepub:liu)n/a
7001 a Bramlage, Peteru Inst Pharmacol and Prevent Med, Germany4 aut
7001 a Kurucova, Janau Edwards Lifesci, Czech Republic4 aut
7001 a Thoenes, Martinu Edwards Lifesci, Switzerland4 aut
7001 a Rottbauer, Wolfgangu Univ Ulm, Germany4 aut
7001 a Geisler, Tobiasu Univ Hosp Tubingen, Germany4 aut
7102 a Univ Hosp Tubingen, Germanyb Cologne Univ, Germany; Heart and Diabet Ctr NRW, Germany4 org
7730 t Heart and Vesselsd : Springerg 35, s. 1735-1745q 35<1735-1745x 0910-8327x 1615-2573
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-167734
8564 8u https://doi.org/10.1007/s00380-020-01653-6

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