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Sökning: onr:"swepub:oai:DiVA.org:liu-180098" > Tailorable Membrane...
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| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 05273naa a2200493 4500 | |
| 001 | oai:DiVA.org:liu-180098 | |
| 003 | SwePub | |
| 008 | 211008s2021 | |||||||||||000 ||eng| | |
| 024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-1800982 URI |
| 024 | 7 | a https://doi.org/10.1002/smll.2021014402 DOI |
| 040 | a (SwePub)liu | |
| 041 | a engb eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a ref2 swepub-contenttype |
| 072 | 7 | a art2 swepub-publicationtype |
| 100 | 1 | a Zhang, Xinu Linköpings universitet,Molekylär ytfysik och nanovetenskap,Tekniska fakulteten4 aut0 (Swepub:liu)xinzh14 |
| 245 | 1 0 | a Tailorable Membrane-Penetrating Nanoplatform for Highly Efficient Organelle-Specific Localization |
| 264 | c 2021-06-25 | |
| 264 | 1 | b Wiley-V C H Verlag GMBH,c 2021 |
| 338 | a electronic2 rdacarrier | |
| 500 | a Funding Agencies|STINT Joint China-Sweden Mobility Project [CH2017-7243]; Swedish Research Council (VR)Swedish Research Council [VR 2019-02409, 2020-05437]; China Scholarship Council (CSC)China Scholarship Council; Science and Technology Development Fund, Macau SAR [019/2017/AMJ, 0114/2019/A2]; Carl Tryggers Stiftelse [CTS 19:379]; Swedish Government strategic faculty grant in material science (SFO, MATLIU) in Advanced Functional Materials (AFM) (VR) [Dnr. 5.1-2015-5959]; Centre in Nano Science and technology at LiTH (CeNano); LiU Cancer network at Linkoping University | |
| 520 | a Given the breadth of currently arising opportunities and concerns associated with nanoparticles for biomedical imaging, various types of nanoparticles have been widely exploited, especially for cellular/subcellular level probing. However, most currently reported nanoparticles either have inefficient delivery into cells or lack specificity for intracellular destinations. The absence of well-defined nanoplatforms remains a critical challenge hindering practical nano-based bio-imaging. Herein, the authors elaborate on a tailorable membrane-penetrating nanoplatform as a carrier with encapsulated actives and decorated surfaces to tackle the above-mentioned issues. The tunable contents in such a versatile nanoplatform offer huge flexibility to reach the expected properties and functions. Aggregation-induced emission luminogen (AIEgen) is applied to achieve sought-after photophysical properties, specific targeting moieties are installed to give high affinity towards different desired organelles, and critical grafting of cell-penetrating cyclic disulfides (CPCDs) to promote cellular uptake efficiency without sacrificing the specificity. Hereafter, to validate its practicability, the tailored nano products are successfully applied to track the dynamic correlation between mitochondria and lysosomes during autophagy. The authors believe that the strategy and described materials can facilitate the development of functional nanomaterials for various life science applications. | |
| 650 | 7 | a NATURVETENSKAPx Kemix Annan kemi0 (SwePub)104992 hsv//swe |
| 650 | 7 | a NATURAL SCIENCESx Chemical Sciencesx Other Chemistry Topics0 (SwePub)104992 hsv//eng |
| 653 | a cell-penetrating cyclic disulfides; autophagy; bioimaging; fluorescent nanoparticles; subcellular targeting | |
| 700 | 1 | a Wang, Chunfeiu Univ Macau, Peoples R China; Univ Macau, Peoples R China4 aut |
| 700 | 1 | a Feng, Gangu Univ Macau, Peoples R China; Univ Macau, Peoples R China4 aut |
| 700 | 1 | a Jiang, Jianxiau Linköpings universitet,Tunnfilmsfysik,Tekniska fakulteten4 aut0 (Swepub:liu)jiaji35 |
| 700 | 1 | a Hu, Jiwenu Linköpings universitet,Molekylär ytfysik och nanovetenskap,Tekniska fakulteten4 aut0 (Swepub:liu)jiwhu45 |
| 700 | 1 | a Du Rietz, Annau Linköpings universitet,Molekylär ytfysik och nanovetenskap,Tekniska fakulteten4 aut0 (Swepub:liu)anndu45 |
| 700 | 1 | a Brommesson, Carolineu Linköpings universitet,Molekylär ytfysik och nanovetenskap,Tekniska fakulteten4 aut0 (Swepub:liu)carsk36 |
| 700 | 1 | a Zhang, Xuanjunu Univ Macau, Peoples R China; Univ Macau, Peoples R China4 aut |
| 700 | 1 | a Ma, Yuguangu South China Univ Technol, Peoples R China4 aut |
| 700 | 1 | a Roberg, Karinu Linköpings universitet,Avdelningen för cellbiologi,Medicinska fakulteten,Region Östergötland, Öron- näsa- och halskliniken4 aut0 (Swepub:liu)karro26 |
| 700 | 1 | a Zhang, Fenglingu Linköpings universitet,Elektroniska och fotoniska material,Tekniska fakulteten4 aut0 (Swepub:liu)fenzh60 |
| 700 | 1 | a Shen, Han-Mingu Univ Macau, Peoples R China; Univ Macau, Peoples R China4 aut |
| 700 | 1 | a Uvdal, Kajsau Linköpings universitet,Molekylär ytfysik och nanovetenskap,Tekniska fakulteten4 aut0 (Swepub:liu)kajuv09 |
| 700 | 1 | a Hu, Zhang-Junu Linköpings universitet,Molekylär ytfysik och nanovetenskap,Tekniska fakulteten4 aut0 (Swepub:liu)zhahu14 |
| 710 | 2 | a Linköpings universitetb Molekylär ytfysik och nanovetenskap4 org |
| 773 | 0 | t Smalld : Wiley-V C H Verlag GMBHg 17:31q 17:31x 1613-6810x 1613-6829 |
| 856 | 4 | u https://liu.diva-portal.org/smash/get/diva2:1601602/FULLTEXT01.pdfx primaryx Raw objecty fulltext:print |
| 856 | 4 | u https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/smll.202101440 |
| 856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-180098 |
| 856 | 4 8 | u https://doi.org/10.1002/smll.202101440 |
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