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Sökning: onr:"swepub:oai:DiVA.org:liu-64317" > Prospective Diary E...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00003980naa a2200385 4500
001oai:DiVA.org:liu-64317
003SwePub
008110119s2011 | |||||||||||000 ||eng|
009oai:prod.swepub.kib.ki.se:122470448
024a https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-643172 URI
024a https://doi.org/10.1007/s10620-010-1468-y2 DOI
024a http://kipublications.ki.se/Default.aspx?queryparsed=id:1224704482 URI
040 a (SwePub)liud (SwePub)ki
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
100a Walter, Susanna Au Östergötlands Läns Landsting,Linköpings universitet,Gastroenterologi och hepatologi,Hälsouniversitetet,Endokrin- och magtarmmedicinska kliniken US4 aut0 (Swepub:liu)suswa35
2451 0a Prospective Diary Evaluation of Unexplained Abdominal Pain and Bowel Dysfunction :b A Population-Based Colonoscopy Study
264 c 2010-11-10
264 1b Springer,c 2011
338 a print2 rdacarrier
520 a INTRODUCTION: Diagnostic criteria for irritable bowel syndrome (IBS) have not been validated by prospective symptom diary. We investigated the bowel patterns in community subjects with and without non-organic abdominal pain, and compared the symptoms with subjects fulfilling the Rome II criteria (IBS). METHODS: From the Swedish population register, a random sample completed an abdominal symptom questionnaire. Responders were subsequently invited for a clinical evaluation and offered a colonoscopy regardless of whether they had abdominal symptoms or not. A total of 268 subjects underwent colonoscopy, clinical evaluation by gastroenterologist, laboratory investigations, and completed the Rome questionnaire and prospective gastrointestinal (GI) symptom diaries for 1 week. Twenty-three subjects of 268 were excluded due to organic GI disease. RESULTS: Subjects recorded 2,194 bowel movements and 370 abdominal pain episodes on 1,504 days. Subjects with pain in the diary (n = 81) had higher stool frequency (P = 0.01), more urgency (P = 0.0002), feelings of incomplete evacuation (P = 0.0002), nausea (P = 0.0009), and abdominal bloating (P = 0.0005) than subjects without pain (n = 151). Twenty-eight subjects (12%) fulfilled the Rome II criteria for IBS. Together, they had 96 pain episodes but only 4% were improved by defecation; 29% of the pain episodes started or worsened after a meal. Subjects with IBS and other subjects with non-organic abdominal pain (n = 64) exhibited no differences in terms of the proportions of pain episodes improved by defecation, bloating, stool frequency, consistency, or defecatory symptoms. CONCLUSIONS: Current criteria for IBS that rely on recall of the relationship between abdominal pain and bowel disturbance may overcall this association when measured prospectively.
653 a MEDICINE
653 a MEDICIN
700a Kjellström, Larsu Department of Gastroenterology, Sabbatsbergs Hospital, Karolinska Institutet, Stockholm, Sweden4 aut
700a Talley, Nicholas Ju Faculty of Health, University of Newcastle, Newcastle, NSW, Australia4 aut
700a Andreasson, Anna Nixonu Karolinska Institutet,Center for Family and Community Medicine, Karolinska Institutet, Stockholm, Sweden4 aut
700a Nyhlin, Henryu Department of Gastroenterology, Karolinska Institutet, Stockholm, Sweden4 aut
700a Agréus, Larsu Karolinska Institutet,Center for Family and Community Medicine, Karolinska Institutet, Stockholm, Sweden4 aut
710a Linköpings universitetb Gastroenterologi och hepatologi4 org
773t Digestive Diseases and Sciencesd : Springerg 56:5, s. 1444-1451q 56:5<1444-1451x 0163-2116x 1573-2568
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-64317
8564 8u https://doi.org/10.1007/s10620-010-1468-y
8564 8u http://kipublications.ki.se/Default.aspx?queryparsed=id:122470448

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