Sökning: onr:"swepub:oai:DiVA.org:liu-64317" > Prospective Diary E...
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000 | 03980naa a2200385 4500 | |
001 | oai:DiVA.org:liu-64317 | |
003 | SwePub | |
008 | 110119s2011 | |||||||||||000 ||eng| | |
009 | oai:prod.swepub.kib.ki.se:122470448 | |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-643172 URI |
024 | 7 | a https://doi.org/10.1007/s10620-010-1468-y2 DOI |
024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:1224704482 URI |
040 | a (SwePub)liud (SwePub)ki | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Walter, Susanna Au Östergötlands Läns Landsting,Linköpings universitet,Gastroenterologi och hepatologi,Hälsouniversitetet,Endokrin- och magtarmmedicinska kliniken US4 aut0 (Swepub:liu)suswa35 |
245 | 1 0 | a Prospective Diary Evaluation of Unexplained Abdominal Pain and Bowel Dysfunction :b A Population-Based Colonoscopy Study |
264 | c 2010-11-10 | |
264 | 1 | b Springer,c 2011 |
338 | a print2 rdacarrier | |
520 | a INTRODUCTION: Diagnostic criteria for irritable bowel syndrome (IBS) have not been validated by prospective symptom diary. We investigated the bowel patterns in community subjects with and without non-organic abdominal pain, and compared the symptoms with subjects fulfilling the Rome II criteria (IBS). METHODS: From the Swedish population register, a random sample completed an abdominal symptom questionnaire. Responders were subsequently invited for a clinical evaluation and offered a colonoscopy regardless of whether they had abdominal symptoms or not. A total of 268 subjects underwent colonoscopy, clinical evaluation by gastroenterologist, laboratory investigations, and completed the Rome questionnaire and prospective gastrointestinal (GI) symptom diaries for 1 week. Twenty-three subjects of 268 were excluded due to organic GI disease. RESULTS: Subjects recorded 2,194 bowel movements and 370 abdominal pain episodes on 1,504 days. Subjects with pain in the diary (n = 81) had higher stool frequency (P = 0.01), more urgency (P = 0.0002), feelings of incomplete evacuation (P = 0.0002), nausea (P = 0.0009), and abdominal bloating (P = 0.0005) than subjects without pain (n = 151). Twenty-eight subjects (12%) fulfilled the Rome II criteria for IBS. Together, they had 96 pain episodes but only 4% were improved by defecation; 29% of the pain episodes started or worsened after a meal. Subjects with IBS and other subjects with non-organic abdominal pain (n = 64) exhibited no differences in terms of the proportions of pain episodes improved by defecation, bloating, stool frequency, consistency, or defecatory symptoms. CONCLUSIONS: Current criteria for IBS that rely on recall of the relationship between abdominal pain and bowel disturbance may overcall this association when measured prospectively. | |
653 | a MEDICINE | |
653 | a MEDICIN | |
700 | 1 | a Kjellström, Larsu Department of Gastroenterology, Sabbatsbergs Hospital, Karolinska Institutet, Stockholm, Sweden4 aut |
700 | 1 | a Talley, Nicholas Ju Faculty of Health, University of Newcastle, Newcastle, NSW, Australia4 aut |
700 | 1 | a Andreasson, Anna Nixonu Karolinska Institutet,Center for Family and Community Medicine, Karolinska Institutet, Stockholm, Sweden4 aut |
700 | 1 | a Nyhlin, Henryu Department of Gastroenterology, Karolinska Institutet, Stockholm, Sweden4 aut |
700 | 1 | a Agréus, Larsu Karolinska Institutet,Center for Family and Community Medicine, Karolinska Institutet, Stockholm, Sweden4 aut |
710 | 2 | a Linköpings universitetb Gastroenterologi och hepatologi4 org |
773 | 0 | t Digestive Diseases and Sciencesd : Springerg 56:5, s. 1444-1451q 56:5<1444-1451x 0163-2116x 1573-2568 |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-64317 |
856 | 4 8 | u https://doi.org/10.1007/s10620-010-1468-y |
856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:122470448 |
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