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Polarized Light Spe...
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Tesselaar, ErikLinköpings universitet,Brännskadevård,Hälsouniversitetet
(author)
Polarized Light Spectroscopy for Measurement of the Microvascular Response to Local Heating at Multiple Skin Sites
- Article/chapterEnglish2012
Publisher, publication year, extent ...
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2012-11-20
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Informa Healthcare / John Wiley and Sons,2012
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printrdacarrier
Numbers
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LIBRIS-ID:oai:DiVA.org:liu-87225
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https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-87225URI
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https://doi.org/10.1111/j.1549-8719.2012.00203.xDOI
Supplementary language notes
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Language:English
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Summary in:English
Part of subdatabase
Classification
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Subject category:ref swepub-contenttype
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Subject category:art swepub-publicationtype
Notes
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Objective: To evaluate whether TiVi, a technique based on polarized light, could measure the change in RBC concentration during local heating in healthy volunteers. Methods: Using a custom-made transparent heater, forearm skin was heated to 42 degrees C for 40 minutes while the change in RBC concentration was measured with TiVi. The perfusion response during local heating was measured at the same time with Laser Doppler flowmetry. Results: Mean RBC concentration increased (91 +/- 34 vs. 51 +/- 34 A.U. at baseline, p less than 0.001). The spatial heterogeneity of the RBC concentration in the measured skin areas was 26 +/- 6.4% at baseline, and 23 +/- 4.6% after 40 minutes of heating. The mean RBC concentrations in two skin sites were highly correlated (0.98 at baseline and 0.96 after 40 minutes of heating). The change in RBC concentration was less than the change in perfusion, measured with LDF. Unlike with LDF, a neurally mediated peak was not observed with TiVi in most of the test subjects. Conclusions: TiVi is a valuable technique for measuring the microvascular response to local heating in the skin, and offers a high reproducibility for simultaneous measurements at different skin sites, provided carefully controlled experiments are ensured.
Subject headings and genre
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tissue viability imaging; polarization light spectroscopy; local heating; red blood cell concentration; reproducibility
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MEDICINE
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MEDICIN
Added entries (persons, corporate bodies, meetings, titles ...)
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Bergkvist, MaxÖstergötlands Läns Landsting,Hand- och plastikkirurgiska kliniken US
(author)
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Sjöberg, FolkeÖstergötlands Läns Landsting,Linköpings universitet,Brännskadevård,Hälsouniversitetet,Hand- och plastikkirurgiska kliniken US,Anestesi- och operationkliniken US(Swepub:liu)folsj94
(author)
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Farnebo, SimonÖstergötlands Läns Landsting,Linköpings universitet,Kirurgi,Hälsouniversitetet,Hand- och plastikkirurgiska kliniken US(Swepub:liu)simfa69
(author)
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Linköpings universitetBrännskadevård
(creator_code:org_t)
Related titles
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In:Microcirculation: Informa Healthcare / John Wiley and Sons19:8, s. 705-7131073-96881549-8719
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