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Mammography casting...
Mammography casting-type calcification and risk of local recurrence in DCIS: analyses from a randomised study
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- Holmberg, Lars (författare)
- Uppsala universitet,Endokrinkirurgi,Kings Coll London, England
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- Wong, Y N S (författare)
- Kings Coll London, England
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- Tabar, L (författare)
- Uppsala universitet,Institutionen för medicinska vetenskaper,Uppsala University, Sweden
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- Ringberg, Anita (författare)
- Lund University,Lunds universitet,Kirurgi,Forskargrupper vid Lunds universitet,Surgery,Lund University Research Groups,University Hospital MAS, Sweden
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- Karlsson, P (författare)
- Sahlgrens University Hospital, Sweden
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- Arnesson, Lars-Gunnar (författare)
- Östergötlands Läns Landsting,Linköpings universitet,Avdelningen för kliniska vetenskaper,Hälsouniversitetet,Kirurgiska kliniken US
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- Sandelin, K (författare)
- Karolinska Institutet,Karolinska University Hospital, Sweden
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- Anderson, Harald (författare)
- Lund University,Lunds universitet,Medicinsk onkologi,Sektion I,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Medical oncology,Section I,Department of Clinical Sciences, Lund,Faculty of Medicine,Lund University, Sweden
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- Garmo, H (författare)
- Kings Coll London, England
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- Emdin, Stefan (författare)
- Umeå universitet,Kirurgi,Umeå University Hospital, Sweden
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(creator_code:org_t)
- 2013-01-31
- 2013
- Engelska.
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Ingår i: British Journal of Cancer. - : Cancer Research UK. - 0007-0920 .- 1532-1827. ; 108:4, s. 812-819
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Abstract
Ämnesord
Stäng
- Background: We studied the association between mammographic calcifications and local recurrence in the ipsilateral breast. less thanbrgreater than less thanbrgreater thanMethods: Case-cohort study within a randomised trial of radiotherapy in breast conservation for ductal cancer in situ of the breast (SweDCIS). We studied mammograms from cases with an ipsilateral breast event (IBE) and from a subcohort randomly sampled at baseline. Lesions were classified as a density without calcifications, architectural distortion, powdery, crushed stone-like or casting-type calcifications. less thanbrgreater than less thanbrgreater thanResults: Calcifications representing necrosis were found predominantly in younger women. Women with crushed stone or casting-type microcalcifications had higher histopathological grade and more extensive disease. The relative risk (RR) of a new IBE comparing those with casting-type calcifications to those without calcifications was 2.10 (95% confidence interval (Cl) 0.92-4.80). This risk was confined to in situ recurrences; the RR of an IBE associated with casting-type calcifications on the mammogram adjusted for age and disease extent was 16.4 (95% Cl 2.20-140). less thanbrgreater than less thanbrgreater thanConclusion: Mammographic appearance of ductal carcinoma in situ of the breast is prognostic for the risk of an in situ IBE and may also be an indicator of responsiveness to RT in younger women.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cancer and Oncology (hsv//eng)
Nyckelord
- DCIS
- ipsilateral recurrence
- mammographic calcifications
- radiotherapy
- breast-conserving surgery
- randomised trial
- MEDICINE
- MEDICIN
- DCIS
- ipsilateral recurrence
- mammographic calcifications
- radiotherapy
- breast-conserving surgery
- randomised trial
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
Hitta via bibliotek
Till lärosätets databas
- Av författaren/redakt...
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Holmberg, Lars
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Wong, Y N S
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Tabar, L
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Ringberg, Anita
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Karlsson, P
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Arnesson, Lars-G ...
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visa fler...
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Sandelin, K
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Anderson, Harald
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Garmo, H
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Emdin, Stefan
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visa färre...
- Om ämnet
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Cancer och onkol ...
- Artiklar i publikationen
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British Journal ...
- Av lärosätet
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Linköpings universitet
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Lunds universitet
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Karolinska Institutet
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Umeå universitet
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Uppsala universitet