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Sökning: onr:"swepub:oai:DiVA.org:mau-53857" > Influence of Geneti...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00008374naa a2200697 4500
001oai:DiVA.org:mau-53857
003SwePub
008220712s2022 | |||||||||||000 ||eng|
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:mau:diva-538572 URI
0247 a https://doi.org/10.1136/bmjopen-2021-0557792 DOI
040 a (SwePub)mau
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
1001 a Attauabi, Mohamedu Department of Gastroenterology and Hepatology, Herlev Hospital, Herlev, Denmark4 aut
2451 0a Influence of Genetics, Immunity and the Microbiome on the Prognosis of Inflammatory Bowel Disease (IBD Prognosis Study) :b the protocol for a Copenhagen IBD Inception Cohort Study
264 c 2022-06-27
264 1b BMJ Publishing Group Ltd,c 2022
338 a electronic2 rdacarrier
520 a Introduction: Inflammatory bowel diseases (IBD), encompassing Crohn's disease and ulcerative colitis, are chronic, inflammatory diseases of the gastrointestinal tract. We have initiated a Danish population-based inception cohort study aiming to investigate the underlying mechanisms for the heterogeneous course of IBD, including need for, and response to, treatment.Methods and analysis: IBD Prognosis Study is a prospective, population-based inception cohort study of unselected, newly diagnosed adult, adolescent and paediatric patients with IBD within the uptake area of Hvidovre University Hospital and Herlev University Hospital, Denmark, which covers approximately 1 050 000 inhabitants (~20% of the Danish population). The diagnosis of IBD will be according to the Porto diagnostic criteria in paediatric and adolescent patients or the Copenhagen diagnostic criteria in adult patients. All patients will be followed prospectively with regular clinical examinations including ileocolonoscopies, MRI of the small intestine, validated patient-reported measures and objective examinations with intestinal ultrasound. In addition, intestinal biopsies from ileocolonoscopies, stool, rectal swabs, saliva samples, swabs of the oral cavity and blood samples will be collected systematically for the analysis of biomarkers, microbiome and genetic profiles. Environmental factors and quality of life will be assessed using questionnaires and, when available, automatic registration of purchase data. The occurrence and course of extraintestinal manifestations will be evaluated by rheumatologists, dermatologists and dentists, and assessed by MR cholangiopancreatography, MR of the spine and sacroiliac joints, ultrasonography of peripheral joints and entheses, clinical oral examination, as well as panoramic radiograph of the jaws. Fibroscans and dual-energy X-ray absorptiometry scans will be performed to monitor occurrence and course of chronic liver diseases, osteopenia and osteoporosis.Ethics and dissemination: This study has been approved by Ethics Committee of the Capital Region of Denmark (approval number: H-20065831). Study results will be disseminated through publication in international scientific journals and presentation at (inter)national conferences.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Odontologi0 (SwePub)302162 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Dentistry0 (SwePub)302162 hsv//eng
7001 a Madsen, Gorm Roageru Copenhagen Center for Inflammatory Bowel Disease in Children, Adolescents and Adults, Hvidovre Hospital, Hvidovre, Denmark4 aut
7001 a Bendtsen, Flemmingu Gastrounit, Medical Section, Hvidovre Hospital, Hvidovre, Denmark4 aut
7001 a Wewer, Anne Vibekeu The Paediatric Department, Hvidovre Hospital, Hvidovre, Denmark4 aut
7001 a Wilkens, Runeu Gastrounit, Medical Section, Hvidovre Hospital, Hvidovre, Denmark4 aut
7001 a Ilvemark, Johanu Department of Gastroenterology and Hepatology, Herlev Hospital, Herlev, Denmark4 aut
7001 a Vladimirova, Norau Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen, Denmark4 aut
7001 a Jensen, Annette Bøjeru Department of Radiology, Centre for Functional and Diagnostic Imaging and Research, Hvidovre Hospital, Hvidovre, Denmark4 aut
7001 a Jensen, Frank Kriegeru Department of Radiology, Centre for Functional and Diagnostic Imaging and Research, Hvidovre Hospital, Hvidovre, Denmark4 aut
7001 a Hansen, Sanja Bayu Department of Radiology, Centre for Functional and Diagnostic Imaging and Research, Hvidovre Hospital, Hvidovre, Denmark4 aut
7001 a Siebner, Hartwig Romanu Danish Research Centre for Magnetic Resonance, Centre for Functional and Diagnostic Imaging and Research, Hvidovre Hospital, Hvidovre, Denmark4 aut
7001 a Nielsen, Yousef Jesper Wirenfeldtu Department of Radiology, Herlev Hospital, Herlev, Denmark4 aut
7001 a Møller, Jakob Mu Department of Radiology, Herlev Hospital, Herlev, Denmark4 aut
7001 a Thomsen, Henrik Su Department of Radiology, Herlev Hospital, Herlev, Denmark4 aut
7001 a Thomsen, Simon Francisu Department of Dermatology, Bispebjerg Hospital, Kobenhavn, Denmark4 aut
7001 a Ingels, Helene Andrea Sinclairu Department of Paediatrics and Adolescent Medicine, Copenhagen University Hospital, Kobenhavn, Denmark4 aut
7001 a Theede, Klausu Gastrounit, Medical Section, Hvidovre Hospital, Hvidovre, Denmark4 aut
7001 a Boysen, Trineu Gastrounit, Medical Section, Hvidovre Hospital, Hvidovre, Denmark4 aut
7001 a Bjerrum, Jacob Tu Department of Gastroenterology and Hepatology, Herlev Hospital, Herlev, Denmark4 aut
7001 a Jakobsen, Christianu Copenhagen Center for Inflammatory Bowel Disease in Children, Adolescents and Adults, Hvidovre Hospital, Hvidovre, Denmark4 aut
7001 a Dorn-Rasmussen, Mariau Copenhagen Center for Inflammatory Bowel Disease in Children, Adolescents and Adults, Hvidovre Hospital, Hvidovre, Denmark4 aut
7001 a Jansson, Sabineu Copenhagen Center for Inflammatory Bowel Disease in Children, Adolescents and Adults, Hvidovre Hospital, Hvidovre, Denmark4 aut
7001 a Yao, Yiqiuu Department of Dermatology, Bispebjerg Hospital, Kobenhavn, Denmark4 aut
7001 a Burian, Ewa Annau Department of Dermatology, Bispebjerg Hospital, Kobenhavn, Denmark4 aut
7001 a Møller, Frederik Trieru Department of Infectious Disease Epidemiology and Prevention, Statens Serum Institut, Kobenhavn, Denmark4 aut
7001 a Fana, Viktoriau Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Kobenhavn, Denmark4 aut
7001 a Wiell, Charlotteu Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Kobenhavn, Denmark4 aut
7001 a Terslev, Leneu Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet Glostrup, Glostrup, Denmark4 aut
7001 a Østergaard, Mikkelu Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Kobenhavn, Denmark4 aut
7001 a Bertl, Kristinau Malmö universitet,Odontologiska fakulteten (OD),Periodontology4 aut0 (Swepub:mau)ae0620
7001 a Stavropoulos, Andreasu Malmö universitet,Odontologiska fakulteten (OD),Periodontology4 aut0 (Swepub:mau)ac3062
7001 a Seidelin, Jakob Bu Department of Gastroenterology and Hepatology, Herlev Hospital, Herlev, Denmark4 aut
7001 a Burisch, Johanu Copenhagen Center for Inflammatory Bowel Disease in Children, Adolescents and Adults, Hvidovre Hospital, Hvidovre, Denmark4 aut
7102 a Department of Gastroenterology and Hepatology, Herlev Hospital, Herlev, Denmarkb Copenhagen Center for Inflammatory Bowel Disease in Children, Adolescents and Adults, Hvidovre Hospital, Hvidovre, Denmark4 org
7730 t BMJ Opend : BMJ Publishing Group Ltdg 12:6, s. e055779-e055779q 12:6<e055779-e055779x 2044-6055
8564 u https://doi.org/10.1136/bmjopen-2021-055779y Fulltext
8564 u https://mau.diva-portal.org/smash/get/diva2:1682894/FULLTEXT01.pdfx primaryx Raw objecty fulltext:print
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:mau:diva-53857
8564 8u https://doi.org/10.1136/bmjopen-2021-055779

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