Sökning: onr:"swepub:oai:DiVA.org:oru-61215" > Stress resilience a...
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000 | 04281naa a2200397 4500 | |
001 | oai:DiVA.org:oru-61215 | |
003 | SwePub | |
008 | 171003s2017 | |||||||||||000 ||eng| | |
009 | oai:prod.swepub.kib.ki.se:136634779 | |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-612152 URI |
024 | 7 | a https://doi.org/10.1136/jech-2016-2087062 DOI |
024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:1366347792 URI |
040 | a (SwePub)orud (SwePub)ki | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Kennedy, Beatrice,d 1982-u Örebro universitet,Institutionen för medicinska vetenskaper,Clinical Epidemiology and Biostatistics4 aut0 (Swepub:oru)beky |
245 | 1 0 | a Stress resilience and cancer risk :b a nationwide cohort study |
264 | c 2017-08-08 | |
264 | 1 | a London, UK :b BMJ Publishing Group Ltd,c 2017 |
338 | a print2 rdacarrier | |
520 | a Background: Stress resilience is recognised as a determinant of both psychiatric and somatic health, but the potential link between stress resilience and cancer development has not been explored.Methods: In this nationwide cohort study, we examined the association between stress resilience in adolescence and subsequent cancer risk. We identified a cohort of 284 257 Swedish men, born 1952-1956, who underwent compulsory military enlistment examinations including measures of psychological stress resilience (median age 18 years). The resulting score was categorised as low, moderate and high stress resilience. Individuals diagnosed with cancer during the follow-up time were identified through data linkage to the Swedish Cancer Register.Results: Lowest stress resilience, compared with the highest, was associated with increased risks of liver (HR: 4.73, 95% CI 2.73 to 8.19) and lung (HR: 2.75, 95% CI 2.02 to 3.74) cancer after adjusting for markers of socioeconomic circumstances in childhood (p for trend <0.001 for both cancer types). Further adjustment for cognitive and physical fitness at conscription assessment had a marginal influence. In contrast, men with low stress resilience had a decreased risk of being diagnosed with prostate cancer (HR: 0.65, 95% CI 0.56 to 0.76) and malignant melanoma (HR: 0.65, 95% CI 0.55 to 0.76).Conclusion: We conclude that adolescent stress resilience, plausibly by influencing behavioural choices and social patterns, constitutes an important determinant of adult cancer occurrence. Increased awareness of longterm consequences in susceptible individuals may help direct future efforts to reduce cancer burden in adults. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Hälsovetenskapx Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi0 (SwePub)303022 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Health Sciencesx Public Health, Global Health, Social Medicine and Epidemiology0 (SwePub)303022 hsv//eng |
700 | 1 | a Fang, Fangu Karolinska Institutet4 aut |
700 | 1 | a Valdimarsdottir, Unnuru Karolinska Institutet4 aut |
700 | 1 | a Udumyan, Ruzan,d 1971-u Örebro universitet,Institutionen för medicinska vetenskaper,Clinical Epidemiology and Biostatistics4 aut0 (Swepub:oru)run |
700 | 1 | a Montgomery, Scott,d 1961-u Karolinska Institutet,Örebro universitet,Institutionen för medicinska vetenskaper,Department of Epidemiology and Public Health, University College London, London, UK; Clinical Epidemiology Unit, Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden,Clinical Epidemiology and Biostatistics4 aut0 (Swepub:oru)smy |
700 | 1 | a Fall, Katja,d 1971-u Örebro universitet,Institutionen för medicinska vetenskaper,Clinical Epidemiology and Biostatistics4 aut0 (Swepub:oru)kafl |
710 | 2 | a Örebro universitetb Institutionen för medicinska vetenskaper4 org |
773 | 0 | t Journal of Epidemiology and Community Healthd London, UK : BMJ Publishing Group Ltdg 71:10, s. 947-953q 71:10<947-953x 0143-005Xx 1470-2738 |
856 | 4 | u https://doi.org/10.1136/jech-2016-208706y Fulltext |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-61215 |
856 | 4 8 | u https://doi.org/10.1136/jech-2016-208706 |
856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:136634779 |
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