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Vitamin D levels af...
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Sallander, EllinorKarolinska Institutet, Stockholm, Sweden
(författare)
Vitamin D levels after UVB radiation : effects by UVA additions in a randomized controlled trial
- Artikel/kapitelEngelska2013
Förlag, utgivningsår, omfång ...
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2013-10-30
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Wiley-Blackwell Publishing Inc.2013
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printrdacarrier
Nummerbeteckningar
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LIBRIS-ID:oai:DiVA.org:oru-78450
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https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-78450URI
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https://doi.org/10.1111/phpp.12076DOI
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http://kipublications.ki.se/Default.aspx?queryparsed=id:127728034URI
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Språk:engelska
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Sammanfattning på:engelska
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Ämneskategori:ref swepub-contenttype
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Ämneskategori:art swepub-publicationtype
Anmärkningar
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BACKGROUND: Ultraviolet B (UVB) radiation increases the serum level of 25-hydroxyvitamin D [25(OH)D]. However, the impact of UVA on vitamin D synthesis by UVB is poorly understood clinically.OBJECTIVE: To examine how different combinations of UVA and UVB radiation affect S-25(OH)D for the same vitamin D-weighted exposure.MATERIALS AND METHODS: Healthy participants were recruited and subsequently divided into four comparable groups regarding initial 25(OH)D value. The different radiations given were whole-body UVB (n = 23), UVAB (n = 23) and UVA (n = 10). The controls (n = 19) had no intervention. The exposure times were chosen to give the same calculated vitamin D effective dose (suberythemal exposures ≤1 standard erythema dose). Blood samples were collected before the first irradiation (t0), immediately after the last (fifth) irradiation (t1) and then after another 2 days after the last (fifth) irradiation (t2).RESULTS: UVB and UVAB radiation significantly increased 25(OH)D levels. In the UVA group the increase was less with the same vitamin D-weighted radiation dose.CONCLUSIONS: Short sessions of UVB or UVAB radiation with the same vitamin D-weighted exposure increased 25(OH)D levels. The UVA dose does not influence 25(OH)D levels under short exposure times. However, there was a significantly lower increase of 25(OH)D levels during longer UVA irradiation (≥9 min).
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Biuppslag (personer, institutioner, konferenser, titlar ...)
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Wester, UlfSwedish Radiation Safety Authority, Stockholm, Sweden
(författare)
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Bengtsson, EmilSwedish Radiation Safety Authority, Stockholm, Sweden
(författare)
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Wiegleb Edström, Desirée,1959-Karolinska Institutet(Swepub:oru)dwm
(författare)
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Karolinska Institutet, Stockholm, SwedenSwedish Radiation Safety Authority, Stockholm, Sweden
(creator_code:org_t)
Sammanhörande titlar
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Ingår i:Photodermatology, Photoimmunology & Photomedicine: Wiley-Blackwell Publishing Inc.29:6, s. 323-3290905-43831600-0781
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