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Search: onr:"swepub:oai:DiVA.org:oru-8653" > Novel type of staph...

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LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00003073naa a2200445 4500
001oai:DiVA.org:oru-8653
003SwePub
008091125s2008 | |||||||||||000 ||eng|
024a https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-86532 URI
024a https://doi.org/10.1128/AAC.00087-082 DOI
040 a (SwePub)oru
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
100a Berglund, Carolinau Örebro universitet,Hälsoakademin4 aut0 (Swepub:oru)cabd
2451 0a Novel type of staphylococcal cassette chromosome mec in a methicillin-resistant Staphylococcus aureus strain isolated in Sweden
264 1c 2008
338 a print2 rdacarrier
500 a Part of thesis: http://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-2443
520 a We identified a novel type of staphylococcal cassette chromosome mec (SCCmec) element carried by methicillin-resistant Staphylococcus aureus (MRSA) strain JCSC6082 isolated in Sweden. The SCCmec element was demarcated by characteristic nucleotide sequences at both ends and was integrated at the 3' end of orfX. The element carried a novel combination of a type 5 ccr gene complex and class C1 mec gene complex. The J regions of the element were homologous to those of the SCCmercury element of S. aureus strain 85/2082, with nucleotide identity greater than 99%. However, the novel SCCmec element from JCSC6082 did not carry the mer operon nor Tn554, suggesting that evolution to SCCmec could have been from a common ancestor by acquisition of the class C1 mec gene complex. The novel SCCmec element from JCSC6082 was flanked by a novel SCC-like chromosome cassette (CC6082), which was demarcated by two direct repeats and could be excised from the chromosome independently of the SCCmec element. Our data suggest that novel SCCmec elements can be generated on the staphylococcal chromosome through the recombination between extant SCC elements and mec gene complexes.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Medicinska och farmaceutiska grundvetenskaperx Mikrobiologi inom det medicinska området0 (SwePub)301092 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Basic Medicinex Microbiology in the medical area0 (SwePub)301092 hsv//eng
653 a MEDICINE
653 a MEDICIN
653 a Microbiology, immunology, infectious diseases
653 a Mikrobiologi, immunologi, infektionssjukdomar
653 a Medicine
653 a Medicin
653 a Immunologi
653 a Immunology
700a Ito, Teruyo4 aut
700a Ikeda, Megumi4 aut
700a Ma, Xiao Xue4 aut
700a Söderquist, Bou Örebro universitet,Hälsoakademin4 aut0 (Swepub:oru)bost
700a Hiramatsu, Keiichi4 aut
710a Örebro universitetb Hälsoakademin4 org
773t Antimicrobial Agents and Chemotherapyg 52:10, s. 3512-3516q 52:10<3512-3516x 0066-4804x 1098-6596
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-8653
8564 8u https://doi.org/10.1128/AAC.00087-08

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