Sökning: onr:"swepub:oai:DiVA.org:oru-95277" > Performance of crea...
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000 | 10496naa a2200841 4500 | |
001 | oai:DiVA.org:oru-95277 | |
003 | SwePub | |
008 | 211029s2022 | |||||||||||000 ||eng| | |
009 | oai:prod.swepub.kib.ki.se:148240454 | |
009 | oai:DiVA.org:uu-457614 | |
009 | oai:lup.lub.lu.se:c2a98b97-9be3-441c-9fbd-00722d5b35c6 | |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-952772 URI |
024 | 7 | a https://doi.org/10.1111/bcp.151322 DOI |
024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:1482404542 URI |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-4576142 URI |
024 | 7 | a https://lup.lub.lu.se/record/c2a98b97-9be3-441c-9fbd-00722d5b35c62 URI |
040 | a (SwePub)orud (SwePub)kid (SwePub)uud (SwePub)lu | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Delanaye, Pierreu Department of Nephrology-Dialysis-Transplantation, University of Liège (ULg CHU), CHU Sart Tilman, Liège, Belgium; Department of Nephrology-Dialysis-Apheresis, Hopital Universitaire Caremeau, Nimes, France4 aut |
245 | 1 0 | a Performance of creatinine-based equations to estimate glomerular filtration rate with a methodology adapted to the context of drug dosage adjustment |
264 | c 2021-12-03 | |
264 | 1 | b Wiley-Blackwell Publishing Inc.c 2022 |
338 | a print2 rdacarrier | |
520 | a AIM: The Cockcroft-Gault (CG) creatinine-based equation is still used to estimate glomerular filtration rate (eGFR) for drug dosage adjustment. Incorrect eGFR may lead to hazardous over- or underdosing METHODS: In a cross-sectional analysis, CG was validated against measured GFR (mGFR) in 14,804 participants and compared with the Modification-of-Diet-in-Renal-Diseases (MDRD), Chronic-Kidney-Disease-Epidemiology (CKD-EPI), Lund-Malmö-Revised (LMR), and European-Kidney-Function-Consortium (EKFC) equations. Validation focused on bias, imprecision, and accuracy (percentage of estimates within ±30% of mGFR, P30), overall and stratified for mGFR, age, and body mass index at mGFR <60 mL/min, as well as classification in mGFR stages.RESULTS: The CG equation performed worse than the other equations, overall and in mGFR, age and BMI subgroups in terms of bias (systematic overestimation), imprecision and accuracy except for patients ≥65 years where bias and P30 were similar to MDRD and CKD-EPI, but worse than LMR and EKFC. In subjects with mGFR<60 mL/min and at BMI [18.5-25[kg/m2 , all equations performed similarly and for BMI<18.5kg/m2 CG and LMR had the best results though all equations had poor P30-accuracy. At BMI≥25kg/m2 the bias of the CG increased with increasing BMI (+17.2mL/min at BMI≥40kg/m2 ). The four more recent equations also classified mGFR stages better than CG.CONCLUSIONS: The CG equation showed poor ability to estimate GFR overall and in analyses stratified for GFR, age, and BMI. CG was inferior to correctly classify the patients in the mGFR staging compared to more recent creatinine-based equations. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Urologi och njurmedicin0 (SwePub)302142 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Urology and Nephrology0 (SwePub)302142 hsv//eng |
653 | a Chronic kidney disease | |
653 | a drug adjustment | |
653 | a glomerular filtration rate | |
653 | a chronic kidney disease | |
653 | a drug adjustment | |
653 | a glomerular filtration rate | |
700 | 1 | a Björk, Jonasu Lund University,Lunds universitet,Avdelningen för arbets- och miljömedicin,Institutionen för laboratoriemedicin,Medicinska fakulteten,Division of Occupational and Environmental Medicine, Lund University,Department of Laboratory Medicine,Faculty of Medicine,Skåne University Hospital4 aut0 (Swepub:lu)ymed-jbj |
700 | 1 | a Courbebaisse, Marieu Physiology Department, Georges Pompidou European Hospital, Assistance Publique Hôpitaux de Paris, Paris Descartes University, INSERM U1151-CNRS UMR8253, Paris, France.,Paris Diderot University4 aut |
700 | 1 | a Couzi, Lionelu CHU de Bordeaux, Nephrologie - Transplantation - Dialyse, Université de Bordeaux, CNRS-UMR 5164 Immuno ConcEpT, France.4 aut |
700 | 1 | a Ebert, Natalieu Charité Universitätsmedizin Berlin, Institute of Public Health, Berlin, Germany.,Charité - University Medicine Berlin4 aut |
700 | 1 | a Eriksen, Björn O.u Metabolic and Renal Research Group, UiT The Arctic University of Norway, Tromsö, Norway.4 aut |
700 | 1 | a Dalton, R Neilu The Wellchild Laboratory, Evelina London Children's Hospital, London, United Kingdom.,Evelina London Children's Healthcare4 aut |
700 | 1 | a Dubourg, Laurenceu Néphrologie, Dialyse, Hypertension et Exploration Fonctionnelle Rénale, Hôpital Edouard Herriot, Hospices Civils de Lyon, France.,Claude Bernard University Lyon 14 aut |
700 | 1 | a Gaillard, Francoisu Renal Transplantation Department, Assistance Publique-Hôpitaux de Paris (AP-HP), France,Hôpital Edouard Herriot4 aut |
700 | 1 | a Garrouste, Cyrilu Department of Nephrology, Clermont-Ferrand University Hospital, Clermont-Ferrand, France.4 aut |
700 | 1 | a Grubb, Andersu Lund University,Lunds universitet,Cystatin C, njursjukdom, amyloidos och antibiotika,Forskargrupper vid Lunds universitet,Cystatin C, renal disease, amyloidosis and antibiotics,Lund University Research Groups,Skåne University Hospital4 aut0 (Swepub:lu)kkem-agr |
700 | 1 | a Jacquemont, Lolau Renal Transplantation Department, CHU Nantes, Nantes University, Nantes, France.,University of Nantes4 aut |
700 | 1 | a Hansson, Magnusu Karolinska Institute,Karolinska Institutet,Function area Clinical Chemistry, Karolinska University Laboratory, Karolinska University Hospital Huddinge and Department of Laboratory Medicine, Karolinska Institute, Stockholm, Sweden.4 aut |
700 | 1 | a Kamar, Nassimu Department of Nephrology, Dialysis and Organ Transplantation, CHU Rangueil, INSERM U1043, IFR -BMT, University Paul Sabatier, Toulouse, France.,Rangueil Hospital4 aut |
700 | 1 | a Lamb, Edmund J.u Clinical Biochemistry, East Kent Hospitals University NHS Foundation Trust, Canterbury, United Kingdom.4 aut |
700 | 1 | a Legendre, Christopheu Hôpital Necker, AP-HP & Université Paris Descartes, Paris, France.,Necker-Enfants Malades Hospital4 aut |
700 | 1 | a Littmann, Karinu Karolinska Institute,Karolinska Institutet,Department of Medicine Huddinge (MedH), Karolinska Institute, Huddinge, Sweden.4 aut |
700 | 1 | a Mariat, Christopheu Service de Néphrologie, Dialyse et Transplantation Rénale, Hôpital Nord, CHU de Saint-Etienne, France.4 aut |
700 | 1 | a Melsom, Toralfu Metabolic and Renal Research Group, UiT The Arctic University of Norway, Tromsö, Norway,Service de Néphrologie, Hémodialyse, Aphérèses et Transplantation Rénale, Hôpital Michallon, CHU Grenoble-Alpes, France.4 aut |
700 | 1 | a Rostaing, Lionelu Service de Néphrologie, Hémodialyse, Aphérèses et Transplantation Rénale, Hôpital Michallon, CHU Grenoble-Alpes, France,Division of Nephrology and Hypertension, Mayo Clinic, Rochester, MN, USA.,Grenoble University Hospital4 aut |
700 | 1 | a Rule, Andrew D.u Division of Nephrology and Hypertension, Mayo Clinic, Rochester, MN, USA.,Mayo Clinic Minnesota4 aut |
700 | 1 | a Schaeffner, Elkeu Charité Universitätsmedizin Berlin, Institute of Public Health, Berlin, Germany,Division of Nephrology and Hypertension, Mayo Clinic, Rochester, MN, USA.,Charité - University Medicine Berlin4 aut |
700 | 1 | a Sundin, Per-Ola,d 1971-u Örebro University,Örebro universitet,Institutionen för medicinska vetenskaper,Region Örebro län,Department of Geriatrics, School of Medical Sciences, Örebro University, Örebro, Sweden.4 aut0 (Swepub:oru)pasn |
700 | 1 | a Berg, Ullau Karolinska Institutet,Department of Clinical Science, Intervention and Technology, Division of Pediatrics, Karolinska Institutet, Karolinska University Hospital Huddinge, Stockholm, Sweden.4 aut |
700 | 1 | a Åsling-Monemi, Kajsau Department of Clinical Science, Intervention and Technology, Division of Pediatrics, Karolinska Institutet, Karolinska University Hospital Huddinge, Stockholm, Sweden.4 aut |
700 | 1 | a Selistre, Lucianou Mestrado em Ciências da Saúde -Universidade Caxias do Sul Foundation CAPES, Brazil.,University of Caxias do Sul4 aut |
700 | 1 | a Åkesson, Annau Lund University,Lunds universitet,Avdelningen för arbets- och miljömedicin,Institutionen för laboratoriemedicin,Medicinska fakulteten,EPI@LUND,Forskargrupper vid Lunds universitet,Division of Occupational and Environmental Medicine, Lund University,Department of Laboratory Medicine,Faculty of Medicine,Lund University Research Groups4 aut0 (Swepub:lu)stat-aas |
700 | 1 | a Larsson, Andersu Uppsala universitet,Klinisk kemi,Academic Medical Center of University of Amsterdam (AMC)4 aut0 (Swepub:uu)andlarss |
700 | 1 | a Bökenkamp, Arendu Uppsala University4 aut |
700 | 1 | a Pottel, Hansu Department of Public Health and Primary Care, KU Leuven Campus Kulak Kortrijk, Kortrijk, Belgium.,Catholic University of Leuven4 aut |
700 | 1 | a Nyman, Ulfu Lund University,Lunds universitet,Institutionen för translationell medicin,Medicinska fakulteten,Diagnostisk radiologi, Malmö,Forskargrupper vid Lunds universitet,LUCC: Lunds universitets cancercentrum,Övriga starka forskningsmiljöer,Department of Translational Medicine,Faculty of Medicine,Radiology Diagnostics, Malmö,Lund University Research Groups,LUCC: Lund University Cancer Centre,Other Strong Research Environments4 aut0 (Swepub:lu)ront-uny |
710 | 2 | a Department of Nephrology-Dialysis-Transplantation, University of Liège (ULg CHU), CHU Sart Tilman, Liège, Belgium; Department of Nephrology-Dialysis-Apheresis, Hopital Universitaire Caremeau, Nimes, Franceb Avdelningen för arbets- och miljömedicin4 org |
773 | 0 | t British Journal of Clinical Pharmacologyd : Wiley-Blackwell Publishing Inc.g 88:5, s. 2118-2127q 88:5<2118-2127x 0306-5251x 1365-2125 |
856 | 4 | u http://dx.doi.org/10.1111/bcp.15132y FULLTEXT |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-95277 |
856 | 4 8 | u https://doi.org/10.1111/bcp.15132 |
856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:148240454 |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-457614 |
856 | 4 8 | u https://lup.lub.lu.se/record/c2a98b97-9be3-441c-9fbd-00722d5b35c6 |
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