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Sökning: onr:"swepub:oai:DiVA.org:su-191274" > Risk factors in 50-...

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FältnamnIndikatorerMetadata
00004749naa a2200493 4500
001oai:DiVA.org:su-191274
003SwePub
008210318s2020 | |||||||||||000 ||eng|
009oai:DiVA.org:uu-435906
009oai:prod.swepub.kib.ki.se:145736803
024a https://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-1912742 URI
024a https://doi.org/10.1016/j.jvs.2019.11.0622 DOI
024a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-4359062 URI
024a http://kipublications.ki.se/Default.aspx?queryparsed=id:1457368032 URI
040 a (SwePub)sud (SwePub)uud (SwePub)ki
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
100a Fattahi, Ninau Vastmanland Cty Hosp Västerås, Dept Vasc Surg, Västerås, Sweden.4 aut
2451 0a Risk factors in 50-year-old men predicting development of abdominal aortic aneurysm
264 1b Elsevier BV,c 2020
338 a print2 rdacarrier
520 a Background: Abdominal aortic aneurysm (AAA) is a potentially lethal condition associated with several well-known risk factors including age, smoking, and male sex. The aim of this study was to identify risk factors predicting future development of AAA, which could influence future prevention strategies.Methods: This study collected the data sets of the Westmannia Cardiovascular Risk Factors Study (WICTORY) from 1990 to 1999 and combined them with cases of individuals who have undergone ultrasound examination of the infrarenal aortic diameter as part of the Vastmanland County's ongoing AAA screening program that commenced in 2007 or for other purposes. The study analyzed 5817 men aged 50 years at the time they participated in WICTORY and who underwent an ultrasound examination of the infrarenal aorta on average 15 years later.Results: The prevalence of AAA in our study was 2.6%. Age, smoking status, angina pectoris treatment, prior myocardial infarction, blood pressure treatment, body mass index, waist circumference, systolic blood pressure, heart rate, and total cholesterol level were found to be associated with the development of AAA later in life in the univariate analysis. In the multivariate analysis, current smokers at age 50 years had 11 times higher risk for later development of AAA (hazard ratio [HR], 11.178; confidence interval [CI], 6.277-19.908; P < .001). Former smokers did not suffer a similar risk of AAA development. Elevated total cholesterol concentration at baseline was associated with later AAA development (HR, 1.275; CI, 1.119-1.451; P < .001), as were increasing age (HR, 1.702; CI, 1.153-2.512; P = .007) and waist circumference (HR, 1.019; CI, 1.002-1.037; P = .031).Conclusions: Both the well-known and the somewhat less established possible predictors for future development of AAA identified in this study can support improvement of strategic preventive measures toward specific risk groups and thereby possibly reduce the risk for development of AAA later in life or at least increase the possibility of an early diagnosis in patients with intact AAA.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Kardiologi0 (SwePub)302062 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cardiac and Cardiovascular Systems0 (SwePub)302062 hsv//eng
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Kirurgi0 (SwePub)302122 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Surgery0 (SwePub)302122 hsv//eng
653 a Abdominal aortic aneurysm
653 a Cardiovascular risk factors
653 a Screening
653 a Prediction
653 a Epidemiology
653 a Ultrasound
700a Rosenblad, Andreasu Stockholms universitet,Statistiska institutionen,Uppsala University, Sweden4 aut
700a Kragsterman, Björnu Uppsala universitet,Kärlkirurgi,Vastmanland Cty Hosp Västerås, Dept Vasc Surg, Västerås, Sweden.4 aut0 (Swepub:uu)bjkra123
700a Hultgren, Rebeckau Karolinska Institutet4 aut
700a Karlsson, Andreas,c Fil. dr,d 1973-u Uppsala universitet,Klinisk diabetologi och metabolism,Stockholm Univ, Dept Stat, Stockholm, Sweden.4 aut0 (Swepub:uu)ankar957
710a Vastmanland Cty Hosp Västerås, Dept Vasc Surg, Västerås, Sweden.b Statistiska institutionen4 org
773t Journal of Vascular Surgeryd : Elsevier BVg 72:4, s. 1337-1346q 72:4<1337-1346x 0741-5214x 1097-6809
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-191274
8564 8u https://doi.org/10.1016/j.jvs.2019.11.062
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-435906
8564 8u http://kipublications.ki.se/Default.aspx?queryparsed=id:145736803

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