Sökning: onr:"swepub:oai:DiVA.org:su-31807" > Age-related loss of...
Fältnamn | Indikatorer | Metadata |
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000 | 03168naa a2200493 4500 | |
001 | oai:DiVA.org:su-31807 | |
003 | SwePub | |
008 | 091127s2009 | |||||||||||000 ||eng| | |
009 | oai:prod.swepub.kib.ki.se:118915584 | |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-318072 URI |
024 | 7 | a https://doi.org/10.1016/j.neuroscience.2009.03.0742 DOI |
024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:1189155842 URI |
040 | a (SwePub)sud (SwePub)ki | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Larsson, Mariau Stockholms universitet,Perception och psykofysik,Stockholm Brain Institute, Stockholm, Sweden4 aut0 (Swepub:su)malar |
245 | 1 0 | a Age-related loss of olfactory sensitivity :b Association to dopamine transporter binding in putamen |
264 | 1 | b Elsevier Ltd.c 2009 |
338 | a print2 rdacarrier | |
500 | a The present research was supported by grants from the Swedish Research Council to Maria Larsson, and by grants from the Swedish Research Council and Swedish Brain Power to Lars Bäckman. | |
520 | a The relationship between age-related reductions in the binding potential for the striatal dopamine transporter (DAT) and age-related deficits in olfactory sensitivity was examined in 12 subjects ranging from 36 to 82 years of age. Positron emission tomography (PET) and the radioligand [11C]β-CIT-FE were used to determine DAT binding in two striatal regions, the caudate and the putamen. The results showed age-related losses of DAT binding from early to late adulthood of similar size for caudate and putamen, and there was a pronounced age deterioration in olfactory sensitivity. Importantly, the age-related olfactory deficit was associated with reductions in DAT binding in putamen, but not caudate. Also, DAT binding in putamen added systematic variance in odor threshold after controlling for age. The findings indicate that DAT binding in putamen is related to age-related olfactory deficits, as well as to odor sensitivity independently of age. | |
650 | 7 | a SAMHÄLLSVETENSKAPx Psykologi0 (SwePub)5012 hsv//swe |
650 | 7 | a SOCIAL SCIENCESx Psychology0 (SwePub)5012 hsv//eng |
653 | a olfaction | |
653 | a dopamine | |
653 | a striatum | |
653 | a putamen | |
653 | a aging | |
653 | a Psychology | |
653 | a Psykologi | |
653 | a Psychology | |
653 | a psykologi | |
700 | 1 | a Farde, L.u Karolinska Institutet4 aut |
700 | 1 | a Hummel, T.u University of Dresden Medical School4 aut |
700 | 1 | a Witt, M.u University of Dresden Medical School4 aut |
700 | 1 | a Erixon Lindroth, N.u Karolinska Institutet4 aut |
700 | 1 | a Bäckman, Larsu Karolinska Institutet4 aut |
710 | 2 | a Stockholms universitetb Perception och psykofysik4 org |
773 | 0 | t Neuroscienced : Elsevier Ltd.g 161:2, s. 422-426q 161:2<422-426x 0306-4522x 1873-7544 |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-31807 |
856 | 4 8 | u https://doi.org/10.1016/j.neuroscience.2009.03.074 |
856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:118915584 |
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