Sökning: onr:"swepub:oai:DiVA.org:umu-12687" > The molecular compo...
Fältnamn | Indikatorer | Metadata |
---|---|---|
000 | 03103naa a2200457 4500 | |
001 | oai:DiVA.org:umu-12687 | |
003 | SwePub | |
008 | 071130s2004 | |||||||||||000 ||eng| | |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-126872 URI |
040 | a (SwePub)umu | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Agarkova, Irinau ETH-Zurich Hoenggerberg4 aut |
245 | 1 0 | a The molecular composition of the sarcomeric M-band correlates with muscle fiber type |
264 | 1 | c 2004 |
338 | a print2 rdacarrier | |
520 | a The M-band is the transverse structure that cross-links the thick filaments in the center and provides a perfect alignment of the A-band in the activated sarcomere. The molecular composition of the M-bands in adult mouse skeletal muscle is fiber-type dependent. All M-bands in fast fibers contain M-protein while M-bands in slow fibers contain a significant proportion of the EH-myomesin isoform, previously detected only in embryonic heart muscle. This fiber-type specificity develops during the first postnatal weeks. However, the ratio between the amounts of myosin and of myomesin, taken as sum of both isoforms, remains nearly constant in all studied muscles. Ultrastructural analysis demonstrates that some of the soleus fibers show a diffuse appearance of the M-band, resembling the situation in the embryonic heart. A model is proposed to explain the functional consequence of differential M-band composition for the physiological and morphological properties of sarcomeres in different muscle types. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Medicinska och farmaceutiska grundvetenskaper0 (SwePub)3012 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Basic Medicine0 (SwePub)3012 hsv//eng |
653 | a Animals | |
653 | a Hindlimb/chemistry/metabolism | |
653 | a Mice | |
653 | a Microscopy; Electron | |
653 | a Muscle Fibers/*chemistry/metabolism | |
653 | a Muscle Fibers; Slow-Twitch/chemistry/metabolism | |
653 | a Muscle Proteins/chemistry/genetics/metabolism | |
653 | a Muscle; Skeletal/chemistry/metabolism/ultrastructure | |
653 | a Protein Isoforms/chemistry/genetics/metabolism | |
653 | a Sarcomeres/*chemistry/metabolism | |
700 | 1 | a Schoenauer, Romanu ETH-Zurich Hoenggerberg4 aut |
700 | 1 | a Ehler, Elisabethu King×s College London,4 aut |
700 | 1 | a Carlsson, Lenau Umeå universitet,Anatomi4 aut0 (Swepub:umu)leca0003 |
700 | 1 | a Carlsson, Evau Umeå universitet,Anatomi4 aut0 (Swepub:umu)evca0001 |
700 | 1 | a Thornell, Lars-Ericu Umeå universitet,Anatomi4 aut0 (Swepub:umu)lath0002 |
700 | 1 | a Perriard, Jean-Claudeu ETH-Zurich Hoenggerberg4 aut |
710 | 2 | a ETH-Zurich Hoenggerbergb King×s College London,4 org |
773 | 0 | t European Journal of Cell Biologyg 83:5, s. 193-204q 83:5<193-204x 0171-9335 |
856 | 4 | u http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Retrieve&list_uids=15346809&dopt=Citation |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-12687 |
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