Sökning: onr:"swepub:oai:DiVA.org:umu-137053" > Circulating concent...
Fältnamn | Indikatorer | Metadata |
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000 | 08563naa a2201105 4500 | |
001 | oai:DiVA.org:umu-137053 | |
003 | SwePub | |
008 | 170628s2017 | |||||||||||000 ||eng| | |
009 | oai:lup.lub.lu.se:3d99fcd7-2e40-4a10-8263-f211cc9e06de | |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-1370532 URI |
024 | 7 | a https://doi.org/10.3945/ajcn.116.1512412 DOI |
024 | 7 | a https://lup.lub.lu.se/record/3d99fcd7-2e40-4a10-8263-f211cc9e06de2 URI |
040 | a (SwePub)umud (SwePub)lu | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Midttun, Oivindu Bevital AS4 aut |
245 | 1 0 | a Circulating concentrations of biomarkers and metabolites related to vitamin status, one-carbon and the kynurenine pathways in US, Nordic, Asian, and Australian populations |
264 | 1 | b AMER SOC NUTRITION-ASN,c 2017 |
338 | a print2 rdacarrier | |
520 | a Background: Circulating concentrations of biomarkers that are related to vitamin status vary by factors such as diet, fortification, and supplement use. Published biomarker concentrations have also been influenced by the variation across laboratories, which complicates a comparison of results from different studies. Objective: We robustly and comprehensively assessed differences in biomarkers that are related to vitamin status across geographic regions. Design: The trial was a cross-sectional study in which we investigated 38 biomarkers that are related to vitamin status and one-carbon and tryptophan metabolism in serum and plasma from 5314 healthy control subjects representing 20 cohorts recruited from the United States, Nordic countries, Asia, and Australia, participating in the Lung Cancer Cohort Consortium. All samples were analyzed in a centralized laboratory. Results: Circulating concentrations of riboflavin, pyridoxal 5'-phosphate, folate, vitamin B-12, all-trans retinol, 25-hydroxyvitamin D, and a-tocopherol as well as combined vitamin scores that were based on these nutrients showed that the general B-vitamin concentration was highest in the United States and that the B vitamins and lipid soluble vitamins were low in Asians. Conversely, circulating concentrations of metabolites that are inversely related to B vitamins involved in the one-carbon and kynurenine pathways were high in Asians. The high B-vitamin concentration in the United States appears to be driven mainly by multivitamin-supplement users. Conclusions: The observed differences likely reflect the variation in intake of vitamins and, in particular, the widespread multivitamin-supplement use in the United States. The results provide valuable information about the differences in biomarker concentrations in populations across continents. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Hälsovetenskapx Näringslära0 (SwePub)303042 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Health Sciencesx Nutrition and Dietetics0 (SwePub)303042 hsv//eng |
653 | a biomarker | |
653 | a Lung Cancer Cohort Consortium | |
653 | a one-carbon metabolism | |
653 | a tryptophan metabolism | |
653 | a tamin status | |
653 | a Biomarker | |
653 | a Lung Cancer Cohort Consortium | |
653 | a One-carbon metabolism | |
653 | a Tryptophan metabolism | |
653 | a Vitamin status | |
700 | 1 | a Theofylaktopoulou, Despoinau University of Bergen4 aut |
700 | 1 | a McCann, Adrianu Bevital AS4 aut |
700 | 1 | a Fanidi, Anouaru International Agency for Research on Cancer, World Health Organization4 aut |
700 | 1 | a Muller, David C.u International Agency for Research on Cancer, World Health Organization,Imperial College London4 aut |
700 | 1 | a Meyer, Klausu Bevital AS4 aut |
700 | 1 | a Ulvik, Arveu Bevital AS4 aut |
700 | 1 | a Zheng, Weiu Vanderbilt University Medical Center4 aut |
700 | 1 | a Shu, Xiao-Ouu Vanderbilt University Medical Center4 aut |
700 | 1 | a Xiang, Yong-Bingu Shanghai Cancer Institute4 aut |
700 | 1 | a Prentice, Rossu Fred Hutchinson Cancer Research Center4 aut |
700 | 1 | a Thomson, Cynthia A.u University of Arizona4 aut |
700 | 1 | a Pettinger, Maryu Fred Hutchinson Cancer Research Center4 aut |
700 | 1 | a Giles, Graham G.u University of Melbourne,National Cancer Institute, USA4 aut |
700 | 1 | a Hodge, Allisonu University of Melbourne4 aut |
700 | 1 | a Cai, Qiuyinu Vanderbilt University4 aut |
700 | 1 | a Blot, William J.u Vanderbilt University Medical Center4 aut |
700 | 1 | a Wu, Jieu Vanderbilt University Medical Center4 aut |
700 | 1 | a Johansson, Mikaelu Umeå University,Brigham and Women's Hospital / Harvard Medical School4 aut |
700 | 1 | a Hultdin, Johanu Umeå University,Umeå universitet,Klinisk kemi4 aut0 (Swepub:umu)johu0007 |
700 | 1 | a Grankvist, Kjellu Umeå University,Umeå universitet,Klinisk kemi4 aut0 (Swepub:umu)kjgr0002 |
700 | 1 | a Stevens, Victoria L.u American Cancer Society4 aut |
700 | 1 | a McCullough, Marjorie L.u American Cancer Society,University of Pittsburgh Cancer Institute4 aut |
700 | 1 | a Weinstein, Stephanie J.u National Cancer Institute, USA4 aut |
700 | 1 | a Albanes, Demetriusu National Cancer Institute, USA4 aut |
700 | 1 | a Langhammer, Arnulfu Norwegian University of Science and Technology4 aut |
700 | 1 | a Hveem, Kristianu Norwegian University of Science and Technology4 aut |
700 | 1 | a Naess, Marit4 aut |
700 | 1 | a Sesso, Howard D.u Harvard University,Brigham and Women's Hospital / Harvard Medical School4 aut |
700 | 1 | a Gaziano, J. Michael4 aut |
700 | 1 | a Buring, Julie E.u Brigham and Women's Hospital / Harvard Medical School,Harvard University4 aut |
700 | 1 | a Lee, I-Minu Harvard University,Brigham and Women's Hospital / Harvard Medical School4 aut |
700 | 1 | a Severi, Gianlucau Human Genetics Foundation (HuGeF),University of Paris-Saclay4 aut |
700 | 1 | a Zhang, Xuehongu Brigham and Women's Hospital / Harvard Medical School4 aut |
700 | 1 | a Han, Jialiu Harvard University4 aut |
700 | 1 | a Stampfer, Meir J.u Brigham and Women's Hospital / Harvard Medical School,Harvard University4 aut |
700 | 1 | a Smith-Warner, Stephanie A.u Harvard University4 aut |
700 | 1 | a Zeleniuch-Jacquotte, Anneu New York University4 aut |
700 | 1 | a le Marchand, Loicu University of Hawaii at Manoa4 aut |
700 | 1 | a Yuan, Jian-Minu University of Pittsburgh Cancer Institute,University of Pittsburgh4 aut |
700 | 1 | a Butler, Lesley M.4 aut |
700 | 1 | a Koh, Woon-Puayu Duke–NUS Medical School4 aut |
700 | 1 | a Wang, Renweiu University of Pittsburgh Cancer Institute4 aut |
700 | 1 | a Gao, Yu-Tangu Shanghai Jiao Tong University4 aut |
700 | 1 | a Ericson, Ulrikau Lund University,Lunds universitet,Diabetes - kardiovaskulär sjukdom,Forskargrupper vid Lunds universitet,Diabetes - Cardiovascular Disease,Lund University Research Groups4 aut0 (Swepub:lu)medf-upe |
700 | 1 | a Sonestedt, Emilyu Lund University,Lunds universitet,Diabetes - kardiovaskulär sjukdom,Forskargrupper vid Lunds universitet,Nutritionsepidemiologi,Diabetes - Cardiovascular Disease,Lund University Research Groups,Nutrition Epidemiology4 aut0 (Swepub:lu)medf-eso |
700 | 1 | a Ziegler, Regina G.4 aut |
700 | 1 | a Freedman, Neal D.u National Cancer Institute, USA4 aut |
700 | 1 | a Visvanathan, Kalau Johns Hopkins Bloomberg School of Public Health4 aut |
700 | 1 | a Jones, Miranda R.u Johns Hopkins Bloomberg School of Public Health4 aut |
700 | 1 | a Relton, Carolineu University of Newcastle upon Tyne,University of Bristol4 aut |
700 | 1 | a Brennan, Paulu International Agency for Research on Cancer, World Health Organization4 aut |
700 | 1 | a Johansson, Mattiasu International Agency for Research on Cancer, World Health Organization4 aut |
700 | 1 | a Ueland, Per M.u University of Bergen,Haukeland University Hospital4 aut |
700 | 1 | a Næss, Maritu Norwegian University of Science and Technology4 aut |
710 | 2 | a Bevital ASb University of Bergen4 org |
773 | 0 | t American Journal of Clinical Nutritiond : AMER SOC NUTRITION-ASNg 105:6, s. 1314-1326q 105:6<1314-1326x 0002-9165x 1938-3207 |
856 | 4 | u https://academic.oup.com/ajcn/article-pdf/105/6/1314/23801126/ajcn151241.pdf |
856 | 4 | u http://dx.doi.org/10.3945/ajcn.116.151241x freey FULLTEXT |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-137053 |
856 | 4 8 | u https://doi.org/10.3945/ajcn.116.151241 |
856 | 4 8 | u https://lup.lub.lu.se/record/3d99fcd7-2e40-4a10-8263-f211cc9e06de |
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