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Sökning: onr:"swepub:oai:DiVA.org:umu-184905" > Water temperature a...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00004906naa a2200457 4500
001oai:DiVA.org:umu-184905
003SwePub
008210621s2021 | |||||||||||000 ||eng|
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-1849052 URI
0247 a https://doi.org/10.1016/j.envint.2021.1067052 DOI
040 a (SwePub)umu
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
1001 a Cerveny, D.u Department of Wildlife, Fish, and Environmental Studies, Swedish University of Agricultural Sciences (SLU), Umea, Sweden; University of South Bohemia in Ceske Budejovice, Faculty of Fisheries and Protection of Waters, South Bohemian Research Center of Aquaculture and Biodiversity of Hydrocenoses, Zatisi 728/II, Vodnany, Czech Republic4 aut
2451 0a Water temperature affects the biotransformation and accumulation of a psychoactive pharmaceutical and its metabolite in aquatic organisms
264 1b Elsevier,c 2021
338 a electronic2 rdacarrier
520 a Pharmaceutically active compounds (PhACs) have been shown to accumulate in aquatic and riparian food-webs. Yet, our understanding of how temperature, a key environmental factor in nature, affects uptake, biotransformation, and the subsequent accumulation of PhACs in aquatic organisms is limited. In this study, we tested to what extent bioconcentration of an anxiolytic drugs (temazepam and oxazepam) is affected by two temperature regimes (10 and 20 °C) and how the temperature affects the temazepam biotransformation and subsequent accumulation of its metabolite (oxazepam) in aquatic organisms. We used European perch (Perca fluviatilis) and dragonfly larvae (Sympetrum sp.), which represent predator and prey species of high ecological relevance in food chains of boreal and temperate aquatic ecosystems. Experimental organisms were exposed to target pharmaceuticals at a range of concentrations (0.2–6 µg L−1) to study concentration dependent differences in bioconcentration and biotransformation. We found that the bioconcentration of temazepam in perch was significantly reduced at higher temperatures. Also, temperature had a strong effect on temazepam biotransformation in the fish, with the production and subsequent accumulation of its metabolite (oxazepam) being two-fold higher at 20 °C compared to 10 °C. In contrast, we found no temperature dependency for temazepam bioconcentration in dragonfly larvae and no detectable biotransformation of the parent compound that would result in measurable concentrations of oxazepam in this organism. Our results highlight that while organisms may share the same aquatic ecosystem, their exposure to PhACs may change differently across temperature gradients in the environment.
650 7a NATURVETENSKAPx Geovetenskap och miljövetenskapx Miljövetenskap0 (SwePub)105022 hsv//swe
650 7a NATURAL SCIENCESx Earth and Related Environmental Sciencesx Environmental Sciences0 (SwePub)105022 hsv//eng
653 a Aquatic invertebrate
653 a Benzodiazepine
653 a Dragonfly
653 a Drug
653 a Fish
653 a Temazepam
7001 a Fick, Jerkeru Umeå universitet,Kemiska institutionen4 aut0 (Swepub:umu)jefi0001
7001 a Klaminder, Jonatan,d 1976-u Umeå universitet,Institutionen för ekologi, miljö och geovetenskap4 aut0 (Swepub:umu)jokl0001
7001 a McCallum, E. S.u Department of Wildlife, Fish, and Environmental Studies, Swedish University of Agricultural Sciences (SLU), Umea, Sweden4 aut
7001 a Bertram, M. G.u Department of Wildlife, Fish, and Environmental Studies, Swedish University of Agricultural Sciences (SLU), Umea, Sweden4 aut
7001 a Castillo, N. A.u Department of Earth and Environment, Institute of Environment, Florida International University, FL, Miami, United States4 aut
7001 a Brodin, T.u Department of Wildlife, Fish, and Environmental Studies, Swedish University of Agricultural Sciences (SLU), Umea, Sweden4 aut
7102 a Department of Wildlife, Fish, and Environmental Studies, Swedish University of Agricultural Sciences (SLU), Umea, Sweden; University of South Bohemia in Ceske Budejovice, Faculty of Fisheries and Protection of Waters, South Bohemian Research Center of Aquaculture and Biodiversity of Hydrocenoses, Zatisi 728/II, Vodnany, Czech Republicb Kemiska institutionen4 org
7730 t Environment Internationald : Elsevierg 155q 155x 0160-4120x 1873-6750
8564 u https://doi.org/10.1016/j.envint.2021.106705y Fulltext
8564 u https://umu.diva-portal.org/smash/get/diva2:1570360/FULLTEXT01.pdfx primaryx Raw objecty fulltext:print
8564 u https://doi.org/10.1016/j.envint.2021.106705
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-184905
8564 8u https://doi.org/10.1016/j.envint.2021.106705

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