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Obstructive sleep a...
Obstructive sleep apnea is a risk factor for death in patients with stroke : a 10-year follow-up
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- Sahlin, Carin, 1953- (författare)
- Umeå universitet,Lungmedicin
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- Sandberg, Olov (författare)
- Umeå universitet,Geriatrik
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- Gustafson, Yngve (författare)
- Umeå universitet,Geriatrik
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- Bucht, Gösta (författare)
- Umeå universitet,Geriatrik
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- Carlberg, Bo (författare)
- Umeå universitet,Medicin
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- Stenlund, Hans (författare)
- Umeå universitet,Epidemiologi och folkhälsovetenskap
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- Franklin, Karl (författare)
- Umeå universitet,Lungmedicin
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(creator_code:org_t)
- Chicago : American medical association, 2008
- 2008
- Engelska.
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Ingår i: Archives of Internal Medicine. - Chicago : American medical association. - 0003-9926 .- 1538-3679. ; 168:3, s. 297-301
- Relaterad länk:
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https://jamanetwork....
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https://urn.kb.se/re...
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https://doi.org/10.1...
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http://kipublication...
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Abstract
Ämnesord
Stäng
- Background: Sleep apnea occurs frequently among stroke patients, but it is still unknown whether a diagnosis of sleep apnea is an independent risk factor for mortality. We aimed to investigate whether obstructive or central sleep apnea was related to a reduced long-term survival among stroke patients.Methods: One hundred and thirty-two of 151 patients admitted for in-hospital stroke rehabilitation in the catchment area of Umeå from 1 April 1995 to 1 May 1997 underwent overnight sleep apnea recordings at 23 ± 8 days after onset of stroke. All patients were followed-up prospectively for a mean (SD) of 10.0 ± 0.6 years, with death as the primary outcome and no one was lost to follow-up. Obstructive sleep apnea was defined when the obstructive apnea-hypopnea index was over 15 and central sleep apnea when the central apnea-hypopnea index was over 15. Patients with an obstructive and a central apnea-hypopnea index below 15 served as controls.Results: Of 132 enrolled patients, 116 had died at follow-up. The risk of death was higher among the 23 patients with obstructive sleep apnea than controls (adjusted hazard ratio, 1.76; 95% confidence interval 1.05 to 2.95, p=0.03), independent of age, gender, body-mass index, smoking, hypertension, diabetes mellitus, atrial fibrillation, mini-mental state examination and Barthel activity of daily living There was no difference in mortality between the 28 patients with central sleep apnea and controls (adjusted hazard ratio, 1.07; 95 percent confidence interval 0.65 to 1.76, p=0.053).Conclusions: Stroke patients with obstructive sleep apnea run an increased risk of early death. Central sleep apnea was not related to early death among the present patients.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Allmänmedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- General Practice (hsv//eng)
Nyckelord
- obstructive sleep apnéa
- stroke
- death
- positive airway pressure
- Cheyne-Stokes respiration
- breathing disorders
- ischemic stroke
- 1st-ever stroke
- prognosis
- disease
- night
- Cardiovascular medicine
- Kardiovaskulär medicin
- lungmedicin
- Lung Medicine
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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