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| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 43851naa a2202881 4500 | |
| 001 | oai:DiVA.org:umu-202082 | |
| 003 | SwePub | |
| 008 | 230103s2023 | |||||||||||000 ||eng| | |
| 009 | oai:prod.swepub.kib.ki.se:153345889 | |
| 009 | oai:prod.swepub.kib.ki.se:151984045 | |
| 024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-2020822 URI |
| 024 | 7 | a https://doi.org/10.1038/s41588-022-01222-92 DOI |
| 024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:1533458892 URI |
| 024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:1519840452 URI |
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| 100 | 1 | a Fernandez-Rozadilla, Ceresu Edinburgh Cancer Research Centre, Institute of Genomics and Cancer, University of Edinburgh, Edinburgh, United Kingdom; Genomic Medicine Group, Instituto de Investigacion Sanitaria de Santiago, Santiago de Compostela, Spain4 aut |
| 245 | 1 0 | a Deciphering colorectal cancer genetics through multi-omic analysis of 100,204 cases and 154,587 controls of European and east Asian ancestries |
| 264 | c 2022-12-20 | |
| 264 | 1 | b Nature Publishing Group,c 2023 |
| 338 | a print2 rdacarrier | |
| 500 | a Errata: Fernandez-Rozadilla, C., Timofeeva, M., Chen, Z. et al. Author Correction: Deciphering colorectal cancer genetics through multi-omic analysis of 100,204 cases and 154,587 controls of European and east Asian ancestries. Nat Genet (2023). DOI: 10.1038/s41588-023-01334-w | |
| 520 | a Colorectal cancer (CRC) is a leading cause of mortality worldwide. We conducted a genome-wide association study meta-analysis of 100,204 CRC cases and 154,587 controls of European and east Asian ancestry, identifying 205 independent risk associations, of which 50 were unreported. We performed integrative genomic, transcriptomic and methylomic analyses across large bowel mucosa and other tissues. Transcriptome- and methylome-wide association studies revealed an additional 53 risk associations. We identified 155 high-confidence effector genes functionally linked to CRC risk, many of which had no previously established role in CRC. These have multiple different functions and specifically indicate that variation in normal colorectal homeostasis, proliferation, cell adhesion, migration, immunity and microbial interactions determines CRC risk. Crosstissue analyses indicated that over a third of effector genes most probably act outside the colonic mucosa. Our findings provide insights into colorectal oncogenesis and highlight potential targets across tissues for new CRC treatment and chemoprevention strategies. | |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Medicinska och farmaceutiska grundvetenskaperx Medicinsk genetik0 (SwePub)301072 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Basic Medicinex Medical Genetics0 (SwePub)301072 hsv//eng |
| 700 | 1 | a Timofeeva, Mariau Colon Cancer Genetics Group, Medical Research Council Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, United Kingdom; Danish Institute for Advanced Study, Department of Public Health, University of Southern Denmark, Odense, Denmark4 aut |
| 700 | 1 | a Chen, Zhishanu Division of Epidemiology, Department of Medicine, Vanderbilt-Ingram Cancer Center, Vanderbilt Epidemiology Center, Vanderbilt University Medical Center, TN, Nashville, United States4 aut |
| 700 | 1 | a Law, Philipu Division of Genetics and Epidemiology, Institute of Cancer Research, London, United Kingdom4 aut |
| 700 | 1 | a Thomas, Mintau Public Health Sciences Division, Fred Hutchinson Cancer Research Center, WA, Seattle, United States4 aut |
| 700 | 1 | a Schmit, Stephanieu Karolinska Institutet4 aut |
| 700 | 1 | a Díez-Obrero, Virginiau Colorectal Cancer Group, ONCOBELL Program, Bellvitge Biomedical Research Institute, Barcelona, Spain; Oncology Data Analytics Program, Catalan Institute of Oncology, Barcelona, Spain; Consortium for Biomedical Research in Epidemiology and Public Health, Madrid, Madrid, Spain; Department of Clinical Sciences, Faculty of Medicine, University of Barcelona, Barcelona, Spain4 aut |
| 700 | 1 | a Hsu, Liu Public Health Sciences Division, Fred Hutchinson Cancer Research Center, WA, Seattle, United States; Department of Biostatistics, School of Public Health, University of Washington, WA, Seattle, United States4 aut |
| 700 | 1 | a Fernandez-Tajes, Juanu Edinburgh Cancer Research Centre, Institute of Genomics and Cancer, University of Edinburgh, Edinburgh, United Kingdom4 aut |
| 700 | 1 | a Palles, Claireu Institute of Cancer and Genomic Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom4 aut |
| 700 | 1 | a Sherwood, Kittyu Edinburgh Cancer Research Centre, Institute of Genomics and Cancer, University of Edinburgh, Edinburgh, United Kingdom4 aut |
| 700 | 1 | a Briggs, Sarahu Department of Public Health, Richard Doll Building, University of Oxford, Oxford, United Kingdom4 aut |
| 700 | 1 | a Svinti, Victoriau Colon Cancer Genetics Group, Medical Research Council Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, United Kingdom4 aut |
| 700 | 1 | a Donnelly, Kevinu Colon Cancer Genetics Group, Medical Research Council Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, United Kingdom4 aut |
| 700 | 1 | a Farrington, Susanu Colon Cancer Genetics Group, Medical Research Council Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, United Kingdom4 aut |
| 700 | 1 | a Blackmur, Jamesu Colon Cancer Genetics Group, Medical Research Council Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, United Kingdom4 aut |
| 700 | 1 | a Vaughan-Shaw, Peteru Colon Cancer Genetics Group, Medical Research Council Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, United Kingdom4 aut |
| 700 | 1 | a Shu, Xiao-ouu Division of Epidemiology, Department of Medicine, Vanderbilt-Ingram Cancer Center, Vanderbilt Epidemiology Center, Vanderbilt University Medical Center, TN, Nashville, United States4 aut |
| 700 | 1 | a Long, Jirongu Division of Epidemiology, Department of Medicine, Vanderbilt-Ingram Cancer Center, Vanderbilt Epidemiology Center, Vanderbilt University Medical Center, TN, Nashville, United States4 aut |
| 700 | 1 | a Cai, Qiuyinu Division of Epidemiology, Department of Medicine, Vanderbilt-Ingram Cancer Center, Vanderbilt Epidemiology Center, Vanderbilt University Medical Center, TN, Nashville, United States4 aut |
| 700 | 1 | a Guo, Xingyiu Division of Epidemiology, Department of Medicine, Vanderbilt-Ingram Cancer Center, Vanderbilt Epidemiology Center, Vanderbilt University Medical Center, TN, Nashville, United States; Department of Biomedical Informatics, Vanderbilt University School of Medicine, TN, Nashville, United States4 aut |
| 700 | 1 | a Lu, Yingchangu Division of Epidemiology, Department of Medicine, Vanderbilt-Ingram Cancer Center, Vanderbilt Epidemiology Center, Vanderbilt University Medical Center, TN, Nashville, United States4 aut |
| 700 | 1 | a Broderick, Peteru Division of Genetics and Epidemiology, Institute of Cancer Research, London, United Kingdom4 aut |
| 700 | 1 | a Studd, Jamesu Division of Genetics and Epidemiology, Institute of Cancer Research, London, United Kingdom4 aut |
| 700 | 1 | a Huyghe, Jeroenu Public Health Sciences Division, Fred Hutchinson Cancer Research Center, WA, Seattle, United States4 aut |
| 700 | 1 | a Harrison, Tabithau Public Health Sciences Division, Fred Hutchinson Cancer Research Center, WA, Seattle, United States4 aut |
| 700 | 1 | a Conti, Davidu Department of Preventive Medicine, USC Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, CA, Los Angeles, United States4 aut |
| 700 | 1 | a Dampier, Christopheru Center for Public Health Genomics, Department of Public Health Sciences, University of Virginia, VA, Charlottesville, United States4 aut |
| 700 | 1 | a Devall, Mathewu Center for Public Health Genomics, Department of Public Health Sciences, University of Virginia, VA, Charlottesville, United States4 aut |
| 700 | 1 | a Schumacher, Fredricku Department of Population and Quantitative Health Sciences, Case Western Reserve University, OH, Cleveland, United States; Case Comprehensive Cancer Center, Case Western Reserve University, OH, Cleveland, United States4 aut |
| 700 | 1 | a Melas, Marilenau The Steve and Cindy Rasmussen Institute for Genomic Medicine, Nationwide Children’s Hospital, OH, Columbus, United States4 aut |
| 700 | 1 | a Rennert, Gadu Department of Community Medicine and Epidemiology, Lady Davis Carmel Medical Center, Haifa, Israel; Ruth and Bruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel; Clalit National Cancer Control Center, Haifa, Israel4 aut |
| 700 | 1 | a Obón-Santacana, Mireiau Colorectal Cancer Group, ONCOBELL Program, Bellvitge Biomedical Research Institute, Barcelona, Spain; Oncology Data Analytics Program, Catalan Institute of Oncology, Barcelona, Spain; Consortium for Biomedical Research in Epidemiology and Public Health, Madrid, Spain4 aut |
| 700 | 1 | a Martín-Sánchez, Vicenteu Consortium for Biomedical Research in Epidemiology and Public Health, Madrid, Madrid, Spain; Biomedicine Institute, University of León, León, Spain4 aut |
| 700 | 1 | a Moratalla-Navarro, Ferranu Colorectal Cancer Group, ONCOBELL Program, Bellvitge Biomedical Research Institute, Barcelona, Spain; Oncology Data Analytics Program, Catalan Institute of Oncology, Barcelona, Spain; Consortium for Biomedical Research in Epidemiology and Public Health, Madrid, Madrid, Spain; Department of Clinical Sciences, Faculty of Medicine, University of Barcelona, Barcelona, Spain4 aut |
| 700 | 1 | a Oh, Jae Hwanu Center for Colorectal Cancer, National Cancer Center Hospital, National Cancer Center, Gyeonggi-do, South Korea4 aut |
| 700 | 1 | a Kim, Jeongseonu Department of Cancer Biomedical Science, Graduate School of Cancer Science and Policy, National Cancer Center, Gyeonggi-do, South Korea4 aut |
| 700 | 1 | a Jee, Sun Hau Department of Epidemiology and Health Promotion, Graduate School of Public Health, Yonsei University, Seoul, South Korea4 aut |
| 700 | 1 | a Jung, Keum Jiu Department of Epidemiology and Health Promotion, Graduate School of Public Health, Yonsei University, Seoul, South Korea4 aut |
| 700 | 1 | a Kweon, Sun-Seogu Department of Preventive Medicine, Chonnam National University Medical School, Gwangju, South Korea4 aut |
| 700 | 1 | a Shin, Min-Hou Department of Preventive Medicine, Chonnam National University Medical School, Gwangju, South Korea4 aut |
| 700 | 1 | a Shin, Aesunu Department of Preventive Medicine, Seoul National University College of Medicine, Seoul, South Korea; Cancer Research Institute, Seoul National University, Seoul, South Korea4 aut |
| 700 | 1 | a Ahn, Yoon-Oku Department of Preventive Medicine, Seoul National University College of Medicine, Seoul, South Korea4 aut |
| 700 | 1 | a Kim, Dong-Hyunu Department of Social and Preventive Medicine, Hallym University College of Medicine, Okcheon-dong, South Korea4 aut |
| 700 | 1 | a Oze, Isaou Division of Cancer Epidemiology and Prevention, Aichi Cancer Center Research Institute, Nagoya, Japan4 aut |
| 700 | 1 | a Wen, Wanqingu Division of Epidemiology, Department of Medicine, Vanderbilt-Ingram Cancer Center, Vanderbilt Epidemiology Center, Vanderbilt University Medical Center, TN, Nashville, United States4 aut |
| 700 | 1 | a Matsuo, Keitarou Division of Molecular and Clinical Epidemiology, Aichi Cancer Center Research Institute, Nagoya, Japan; Department of Epidemiology, Nagoya University Graduate School of Medicine, Nagoya, Japan4 aut |
| 700 | 1 | a Matsuda, Koichiu Laboratory of Clinical Genome Sequencing, Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, University of Tokyo, Tokyo, Japan4 aut |
| 700 | 1 | a Tanikawa, Chizuu Laboratory of Genome Technology, Human Genome Center, Institute of Medical Science, University of Tokyo, Tokyo, Japan4 aut |
| 700 | 1 | a Ren, Zefangu School of Public Health, Sun Yat-sen University, Guangzhou, China4 aut |
| 700 | 1 | a Gao, Yu-Tangu State Key Laboratory of Oncogenes and Related Genes and Department of Epidemiology, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China4 aut |
| 700 | 1 | a Jia, Wei-Huau State Key Laboratory of Oncology in South China, Cancer Center, Sun Yat-sen University, Guangzhou, China4 aut |
| 700 | 1 | a Hopper, Johnu Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, University of Melbourne, VIC, Melbourne, Australia; Department of Epidemiology, School of Public Health and Institute of Health and Environment, Seoul National University, Seoul, South Korea4 aut |
| 700 | 1 | a Jenkins, Marku Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, University of Melbourne, VIC, Melbourne, Australia4 aut |
| 700 | 1 | a Win, Aung Kou Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, University of Melbourne, VIC, Melbourne, Australia4 aut |
| 700 | 1 | a Pai, Rishu Department of Laboratory Medicine and Pathology, Mayo Clinic Arizona, AZ, Scottsdale, United States4 aut |
| 700 | 1 | a Figueiredo, Janeu Department of Preventive Medicine, USC Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, CA, Los Angeles, United States; Department of Medicine, Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, CA, Los Angeles, United States4 aut |
| 700 | 1 | a Haile, Robertu Division of Oncology, Department of Medicine, Cedars-Sinai Cancer Research Center for Health Equity, CA, Los Angeles, United States4 aut |
| 700 | 1 | a Gallinger, Stevenu Lunenfeld Tanenbaum Research Institute, Mount Sinai Hospital, University of Toronto, ON, Toronto, Canada4 aut |
| 700 | 1 | a Woods, Michaelu Division of Biomedical Sciences, Memorial University of Newfoundland, ON, St. John, Canada4 aut |
| 700 | 1 | a Newcomb, Pollyu Public Health Sciences Division, Fred Hutchinson Cancer Research Center, WA, Seattle, United States; School of Public Health, University of Washington, WA, Seattle, United States4 aut |
| 700 | 1 | a Duggan, Davidu City of Hope National Medical Center, Translational Genomics Research Institute, AZ, Phoenix, United States4 aut |
| 700 | 1 | a Cheadle, Jeremyu Institute of Medical Genetics, Cardiff University, Cardiff, United Kingdom4 aut |
| 700 | 1 | a Kaplan, Richardu MRC Clinical Trials Unit, Medical Research Council, Cardiff, United Kingdom4 aut |
| 700 | 1 | a Maughan, Timothyu MRC Institute for Radiation Oncology, University of Oxford, Oxford, United Kingdom4 aut |
| 700 | 1 | a Kerr, Rachelu Department of Oncology, University of Oxford, Oxford, United Kingdom4 aut |
| 700 | 1 | a Kerr, Davidu Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom4 aut |
| 700 | 1 | a Kirac, Ivau Department of Surgical Oncology, University Hospital for Tumors, Sestre milosrdnice University Hospital Center, Zagreb, Croatia4 aut |
| 700 | 1 | a Böhm, Janu Department of Pathology, Central Finland Health Care District, Jyväskylä, Finland4 aut |
| 700 | 1 | a Mecklin, Lukka-Pekkau Central Finland Health Care District, Jyväskylä, Finland4 aut |
| 700 | 1 | a Jousilahti, Pekkau Department of Health and Welfare, Finnish Institute for Health and Welfare, Helsinki, Finland4 aut |
| 700 | 1 | a Knekt, Paulu Department of Health and Welfare, Finnish Institute for Health and Welfare, Helsinki, Finland4 aut |
| 700 | 1 | a Aaltonen, Lauriu Department of Medical and Clinical Genetics, University of Helsinki, Helsinki, Finland; Genome-Scale Biology Research Program, University of Helsinki, Helsinki, Finland4 aut |
| 700 | 1 | a Rissanen, Harriu Department of Public Health and Welfare, Finnish Institute for Health and Welfare, Helsinki, Finland4 aut |
| 700 | 1 | a Pukkala, Eerou Finnish Cancer Registry, Institute for Statistical and Epidemiological Cancer Research, Helsinki, Finland; Faculty of Social Sciences, Tampere University, Tampere, Finland4 aut |
| 700 | 1 | a Eriksson, Johanu Folkhälsan Research Centre, University of Helsinki, Helsinki, Finland; Human Potential Translational Research Programme, National University of Singapore, Singapore, Singapore; Unit of General Practice and Primary Health Care, University of Helsinki and Helsinki University Hospital, Helsinki, Finland4 aut |
| 700 | 1 | a Cajuso, Tatianau Department of Medical and Clinical Genetics, University of Helsinki, Helsinki, Finland; Genome-Scale Biology Research Program, University of Helsinki, Helsinki, Finland4 aut |
| 700 | 1 | a Hänninen, Ulrikau Department of Medical and Clinical Genetics, University of Helsinki, Helsinki, Finland; Genome-Scale Biology Research Program, University of Helsinki, Helsinki, Finland4 aut |
| 700 | 1 | a Kondelin, Johannau Department of Medical and Clinical Genetics, University of Helsinki, Helsinki, Finland; Genome-Scale Biology Research Program, University of Helsinki, Helsinki, Finland4 aut |
| 700 | 1 | a Palin, Kimmou Department of Medical and Clinical Genetics, University of Helsinki, Helsinki, Finland; Genome-Scale Biology Research Program, University of Helsinki, Helsinki, Finland4 aut |
| 700 | 1 | a Tanskanen, Tomasu Department of Medical and Clinical Genetics, University of Helsinki, Helsinki, Finland; Genome-Scale Biology Research Program, University of Helsinki, Helsinki, Finland4 aut |
| 700 | 1 | a Renkonen-Sinisalo, Laurau Department of Surgery, Abdominal Centre, Helsinki University Hospital, Helsinki, Finland4 aut |
| 700 | 1 | a Zanke, Brentu Department of Oncology, University of Toronto, ON, Toronto, Canada4 aut |
| 700 | 1 | a Männistö, Satuu Department of Public Health and Welfare, Finnish Institute for Health and Welfare, Helsinki, Finland4 aut |
| 700 | 1 | a Albanes, Demetriusu Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, MD, Bethesda, United States4 aut |
| 700 | 1 | a Weinstein, Stephanieu Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, MD, Bethesda, United States4 aut |
| 700 | 1 | a Ruiz-Narvaez, Edwardu Department of Nutritional Sciences, School of Public Health, University of Michigan, MI, Ann Arbor, United States4 aut |
| 700 | 1 | a Palmer, Julieu Slone Epidemiology Center at Boston University, MA, Boston, United States; Department of Medicine, Boston University School of Medicine, MA, Boston, United States4 aut |
| 700 | 1 | a Buchanan, Danielu Colorectal Oncogenomics Group, Department of Clinical Pathology, University of Melbourne, VIC, Parkville, Australia; University of Melbourne Centre for Cancer Research, Victorian Comprehensive Cancer Centre, VIC, Parkville, Australia; Genomic Medicine and Family Cancer Clinic, Royal Melbourne Hospital, VIC, Parkville, Australia4 aut |
| 700 | 1 | a Platz, Elizabethu Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, MD, Baltimore, United States4 aut |
| 700 | 1 | a Visvanathan, Kalau Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, MD, Baltimore, United States4 aut |
| 700 | 1 | a Ulrich, Corneliau Huntsman Cancer Institute and Department of Population Health Sciences, University of Utah, UT, Salt Lake City, United States4 aut |
| 700 | 1 | a Siegel, Erinu Cancer Epidemiology Program, H. Lee Moffitt Cancer Center and Research Institute, FL, Tampa, United States4 aut |
| 700 | 1 | a Brezina, Stefanieu Institute of Cancer Research, Department of Medicine I, Medical University Vienna, Vienna, Austria4 aut |
| 700 | 1 | a Gsur, Andreau Institute of Cancer Research, Department of Medicine I, Medical University Vienna, Vienna, Austria4 aut |
| 700 | 1 | a Campbell, Peteru Department of Epidemiology and Population Health, Albert Einstein College of Medicine, NY, New York, United States4 aut |
| 700 | 1 | a Chang-Claude, Jennyu Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg, Germany; University Medical Centre Hamburg-Eppendorf, University Cancer Centre Hamburg, Hamburg, Germany4 aut |
| 700 | 1 | a Hoffmeister, Michaelu Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, Heidelberg, Germany4 aut |
| 700 | 1 | a Brenner, Hermannu Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, Heidelberg, Germany; Division of Preventive Oncology, German Cancer Research Center and National Center for Tumor Diseases, Heidelberg, Germany; German Cancer Consortium, German Cancer Research Center, Heidelberg, Germany4 aut |
| 700 | 1 | a Slattery, Marthau Department of Internal Medicine, University of Utah, UT, Salt Lake City, United States4 aut |
| 700 | 1 | a Potter, Johnu Public Health Sciences Division, Fred Hutchinson Cancer Research Center, WA, Seattle, United States; Research Centre for Hauora and Health, Massey University, Wellington, New Zealand4 aut |
| 700 | 1 | a Tsilidis, Konstantinosu Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina, Greece; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom4 aut |
| 700 | 1 | a Schulze, Matthiasu Department of Molecular Epidemiology, German Institute of Human Nutrition Potsdam-Rehbruecke, Nuthetal, Germany; Institute of Nutritional Science, University of Potsdam, Potsdam, Germany4 aut |
| 700 | 1 | a Gunter, Marcu Nutrition and Metabolism Branch, International Agency for Research on Cancer, World Health Organization, Lyon, France4 aut |
| 700 | 1 | a Murphy, Neilu Nutrition and Metabolism Branch, International Agency for Research on Cancer, World Health Organization, Lyon, France4 aut |
| 700 | 1 | a Castells, Antoniu Gastroenterology Department, Hospital Clínic, Institut d’Investigacions Biomèdiques August Pi i Sunyer, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas, University of Barcelona, Barcelona, Spain4 aut |
| 700 | 1 | a Castellví-Bel, Sergiu Gastroenterology Department, Hospital Clínic, Institut d’Investigacions Biomèdiques August Pi i Sunyer, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas, University of Barcelona, Barcelona, Spain4 aut |
| 700 | 1 | a Moreira, Leticiau Gastroenterology Department, Hospital Clínic, Institut d’Investigacions Biomèdiques August Pi i Sunyer, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas, University of Barcelona, Barcelona, Spain4 aut |
| 700 | 1 | a Arndt, Volkeru Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, Heidelberg, Germany4 aut |
| 700 | 1 | a Shcherbina, Annau Department of Genetics, Stanford University, CA, Stanford, United States4 aut |
| 700 | 1 | a Stern, Marianau Department of Population and Public Health Sciences, USC Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, CA, Los Angeles, United States; Jeonnam Regional Cancer Center, Chonnam National University Hwasun Hospital, Hwasun, South Korea4 aut |
| 700 | 1 | a Pardamean, Bensu Bioinformatics and Data Science Research Center, Bina Nusantara University, Jakarta, Indonesia4 aut |
| 700 | 1 | a Bishop, Timothyu Leeds Institute of Medical Research at St James’s, University of Leeds, Leeds, United Kingdom4 aut |
| 700 | 1 | a Giles, Grahamu Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, University of Melbourne, VIC, Melbourne, Australia; Cancer Epidemiology Division, Cancer Council Victoria, VIC, Melbourne, Australia; Precision Medicine, School of Clinical Sciences at Monash Health, Monash University, VIC, Clayton, Australia4 aut |
| 700 | 1 | a Southey, Melissau Cancer Epidemiology Division, Cancer Council Victoria, VIC, Melbourne, Australia; Precision Medicine, School of Clinical Sciences at Monash Health, Monash University, VIC, Clayton, Australia; Department of Clinical Pathology, University of Melbourne, VIC, Melbourne, Australia4 aut |
| 700 | 1 | a Idos, Gregoryu Department of Medical Oncology and Center For Precision Medicine, City of Hope National Medical Center, CA, Duarte, United States4 aut |
| 700 | 1 | a McDonnell, Kevinu Ruth and Bruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel; Clalit National Cancer Control Center, Haifa, Israel; Department of Medical Oncology and Center For Precision Medicine, City of Hope National Medical Center, CA, Duarte, United States4 aut |
| 700 | 1 | a Abu-Ful, Zomorodau Department of Community Medicine and Epidemiology, Lady Davis Carmel Medical Center, Haifa, Israel4 aut |
| 700 | 1 | a Greenson, Joelu Ruth and Bruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel; Clalit National Cancer Control Center, Haifa, Israel; Department of Pathology, University of Michigan, MI, Ann Arbor, United States4 aut |
| 700 | 1 | a Shulman, Katerinau Department of Community Medicine and Epidemiology, Lady Davis Carmel Medical Center, Haifa, Israel4 aut |
| 700 | 1 | a Lejbkowicz, Flaviou Department of Community Medicine and Epidemiology, Lady Davis Carmel Medical Center, Haifa, Israel; Clalit National Cancer Control Center, Haifa, Israel; Clalit Health Services, Personalized Genomic Service, Lady Davis Carmel Medical Center, Haifa, Israel4 aut |
| 700 | 1 | a Offit, Kennethu Clinical Genetics Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, NY, New York, United States; Department of Medicine, Weill Cornell Medical College, NY, New York, United States4 aut |
| 700 | 1 | a Su, Yu-Ruu Kaiser Permanente Washington Health Research Institute, WA, Seattle, United States4 aut |
| 700 | 1 | a Steinfelder, Robertu Public Health Sciences Division, Fred Hutchinson Cancer Research Center, WA, Seattle, United States4 aut |
| 700 | 1 | a Keku, Temitopeu Center for Gastrointestinal Biology and Disease, University of North Carolina, NC, Chapel Hill, United States4 aut |
| 700 | 1 | a van Guelpen, Bethanyu Umeå universitet,Wallenberg centrum för molekylär medicin vid Umeå universitet (WCMM),Onkologi4 aut0 (Swepub:umu)beyvan99 |
| 700 | 1 | a Hudson, Thomasu Ontario Institute for Cancer Research, ON, Toronto, Canada4 aut |
| 700 | 1 | a Hampel, Heatheru Division of Human Genetics, Department of Internal Medicine, Ohio State University Comprehensive Cancer Center, OH, Columbus, United States4 aut |
| 700 | 1 | a Pearlman, Rachelu Division of Human Genetics, Department of Internal Medicine, Ohio State University Comprehensive Cancer Center, OH, Columbus, United States4 aut |
| 700 | 1 | a Berndt, Sonjau Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, MD, Bethesda, United States4 aut |
| 700 | 1 | a Hayes, Richardu Division of Epidemiology, Department of Population Health, New York University School of Medicine, NY, New York, United States4 aut |
| 700 | 1 | a Martinez, Marie Elenau Population Sciences, Disparities and Community Engagement, University of California San Diego Moores Cancer Center, La Jolla, CA, United States; Department of Family Medicine and Public Health, University of California San Diego, La Jolla, CA, United States4 aut |
| 700 | 1 | a Thomas, Sushmau Fred Hutchinson Cancer Research Center, WA, Seattle, United States4 aut |
| 700 | 1 | a Corley, Douglasu Division of Research, Kaiser Permanente Northern California, CA, Oakland, United States; Department of Gastroenterology, Kaiser Permanente Medical Center, CA, San Francisco, United States4 aut |
| 700 | 1 | a Pharoah, Paulu Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom4 aut |
| 700 | 1 | a Larsson, Susannau Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden4 aut |
| 700 | 1 | a Yen, Yunu Taipei Medical University, Taipei, Taiwan4 aut |
| 700 | 1 | a Lenz, Heinz-Josefu Department of Medicine, Keck School of Medicine, University of Southern California, CA, Los Angeles, United States4 aut |
| 700 | 1 | a White, Emilyu Public Health Sciences Division, Fred Hutchinson Cancer Research Center, WA, Seattle, United States; Department of Epidemiology, University of Washington School of Public Health, WA, Seattle, United States4 aut |
| 700 | 1 | a Li, Liu Case Comprehensive Cancer Center, Case Western Reserve University, OH, Cleveland, United States4 aut |
| 700 | 1 | a Doheny, Kimberlyu Center for Inherited Disease Research, Department of Genetic Medicine, Johns Hopkins University School of Medicine, MD, Baltimore, United States4 aut |
| 700 | 1 | a Pugh, Elizabethu Center for Inherited Disease Research, Department of Genetic Medicine, Johns Hopkins University School of Medicine, MD, Baltimore, United States4 aut |
| 700 | 1 | a Shelford, Tamekau Center for Inherited Disease Research, Department of Genetic Medicine, Johns Hopkins University School of Medicine, MD, Baltimore, United States4 aut |
| 700 | 1 | a Chan, Andrewu Clinical and Translational Epidemiology Unit, Massachusetts General Hospital and Harvard Medical School, MA, Boston, United States; Division of Gastroenterology, Massachusetts General Hospital and Harvard Medical School, MA, Boston, United States; Channing Division of Network Medicine, Brigham and Women’s Hospital and Harvard Medical School, MA, Boston, United States; Broad Institute of Harvard and MIT, MA, Cambridge, United States; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Harvard University, MA, Boston, United States; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Harvard University, MA, Boston, United States4 aut |
| 700 | 1 | a Cruz-Correa, Marciau Comprehensive Cancer Center, University of Puerto Rico, San Juan, Puerto Rico4 aut |
| 700 | 1 | a Lindblom, Annikau Karolinska Institutet4 aut |
| 700 | 1 | a Hunter, Davidu Department of Epidemiology, Harvard T.H. Chan School of Public Health, Harvard University, MA, Boston, United States; Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom4 aut |
| 700 | 1 | a Joshi, Amitu Clinical and Translational Epidemiology Unit, Massachusetts General Hospital and Harvard Medical School, MA, Boston, United States; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Harvard University, MA, Boston, United States4 aut |
| 700 | 1 | a Schafmayer, Clemensu Department of General Surgery, University Hospital Rostock, Rostock, Germany4 aut |
| 700 | 1 | a Scacheri, Peteru Department of Genetics and Genome Sciences, Case Western Reserve University, OH, Cleveland, United States4 aut |
| 700 | 1 | a Kundaje, Anshulu Department of Genetics, Stanford University, CA, Stanford, United States; Department of Computer Science, Stanford University, CA, Stanford, United States4 aut |
| 700 | 1 | a Nickerson, Deborahu Department of Genome Sciences, University of Washington, WA, Seattle, United States4 aut |
| 700 | 1 | a Schoen, Robertu Department of Medicine and Epidemiology, University of Pittsburgh Medical Center, PA, Pittsburgh, United States4 aut |
| 700 | 1 | a Hampe, Jochenu Department of Medicine I, University Hospital Dresden, Technische Universität Dresden, Dresden, Germany4 aut |
| 700 | 1 | a Stadler, Zsofiau Department of Medicine, Weill Cornell Medical College, NY, New York, United States; Department of Medicine, Memorial Sloan-Kettering Cancer Center, NY, New York, United States4 aut |
| 700 | 1 | a Vodicka, Pavelu Department of Molecular Biology of Cancer, Institute of Experimental Medicine of the Czech Academy of Sciences, Prague, Czech Republic; Institute of Biology and Medical Genetics, First Faculty of Medicine, Charles University, Prague, Czech Republic; Faculty of Medicine and Biomedical Center in Pilsen, Charles University, Pilsen, Czech Republic4 aut |
| 700 | 1 | a Vodickova, Ludmilau Department of Molecular Biology of Cancer, Institute of Experimental Medicine of the Czech Academy of Sciences, Prague, Czech Republic; Institute of Biology and Medical Genetics, First Faculty of Medicine, Charles University, Prague, Czech Republic; Faculty of Medicine and Biomedical Center in Pilsen, Charles University, Pilsen, Czech Republic4 aut |
| 700 | 1 | a Vymetalkova, Veronikau Department of Molecular Biology of Cancer, Institute of Experimental Medicine of the Czech Academy of Sciences, Prague, Czech Republic; Institute of Biology and Medical Genetics, First Faculty of Medicine, Charles University, Prague, Czech Republic; Faculty of Medicine and Biomedical Center in Pilsen, Charles University, Pilsen, Czech Republic4 aut |
| 700 | 1 | a Papadopoulos, Nickolasu Department of Oncology Ludwig Center at the Sidney Kimmel Cancer Center, Johns Hopkins University School of Medicine, MD, Baltimore, United States; Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins University School of Medicine, MD, Baltimore, United States; Department of Pathology, Johns Hopkins School of Medicine, MD, Baltimore, United States4 aut |
| 700 | 1 | a Edlund, Chistopheru Department of Preventive Medicine, USC Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, CA, Los Angeles, United States4 aut |
| 700 | 1 | a Gauderman, Williamu Department of Preventive Medicine, USC Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, CA, Los Angeles, United States4 aut |
| 700 | 1 | a Thomas, Duncanu Department of Preventive Medicine, USC Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, CA, Los Angeles, United States4 aut |
| 700 | 1 | a Shibata, Davidu Department of Surgery, University of Tennessee Health Science Center, TN, Memphis, United States4 aut |
| 700 | 1 | a Toland, Amandau Departments of Cancer Biology and Genetics and Internal Medicine, Comprehensive Cancer Center, Ohio State University, OH, Columbus, United States4 aut |
| 700 | 1 | a Markowitz, Sanfordu Departments of Medicine and Genetics, Case Comprehensive Cancer Center, Case Western Reserve University and University Hospitals of Cleveland, OH, Cleveland, United States4 aut |
| 700 | 1 | a Kim, Andreu Department of Preventive Medicine, USC Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, CA, Los Angeles, United States4 aut |
| 700 | 1 | a Chanock, Stephenu Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, MD, Bethesda, United States4 aut |
| 700 | 1 | a van Duijnhoven, Franzelu Division of Human Nutrition and Health, Wageningen University and Research, Wageningen, Netherlands4 aut |
| 700 | 1 | a Feskens, Edithu Division of Human Nutrition, Wageningen University and Research, Wageningen, Netherlands4 aut |
| 700 | 1 | a Sakoda, Loriu Public Health Sciences Division, Fred Hutchinson Cancer Research Center, WA, Seattle, United States; Division of Research, Kaiser Permanente Northern California, CA, Oakland, United States4 aut |
| 700 | 1 | a Gago-Dominguez, Manuelau Genomic Medicine Group, Galician Public Foundation of Genomic Medicine, Servicio Galego de Saude, Santiago de Compostela, Spain; Instituto de Investigación Sanitaria de Santiago de Compostela, Santiago de Compostela, Spain4 aut |
| 700 | 1 | a Wolk, Alicjau Karolinska Institutet4 aut |
| 700 | 1 | a Naccarati, Alessiou Italian Institute for Genomic Medicine, Candiolo Cancer Institute, Turin, Italy; Candiolo Cancer Institute, Candiolo, Italy4 aut |
| 700 | 1 | a Pardini, Barbarau Italian Institute for Genomic Medicine, Candiolo Cancer Institute, Turin, Italy; Candiolo Cancer Institute, Candiolo, Italy4 aut |
| 700 | 1 | a FitzGerald, Lieselu Cancer Epidemiology Division, Cancer Council Victoria, VIC, Melbourne, Australia; Menzies Institute for Medical Research, University of Tasmania, TAS, Hobart, Australia4 aut |
| 700 | 1 | a Lee, Soo Chinu National University Cancer Institute, Singapore, Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore4 aut |
| 700 | 1 | a Ogino, Shujiu Department of Epidemiology, Harvard T.H. Chan School of Public Health, Harvard University, MA, Boston, United States; Department of Pathology, Brigham and Women’s Hospital, Harvard Medical School, MA, Boston, United States; Cancer Immunology Program, Dana-Farber Harvard Cancer Center, MA, Boston, United States; Broad Institute of MIT and Harvard, MA, Cambridge, United States4 aut |
| 700 | 1 | a Bien, Stephanieu Public Health Sciences Division, Fred Hutchinson Cancer Research Center, WA, Seattle, United States4 aut |
| 700 | 1 | a Kooperberg, Charlesu Public Health Sciences Division, Fred Hutchinson Cancer Research Center, WA, Seattle, United States4 aut |
| 700 | 1 | a Li, Christopheru Public Health Sciences Division, Fred Hutchinson Cancer Research Center, WA, Seattle, United States4 aut |
| 700 | 1 | a Lin, Yiu Public Health Sciences Division, Fred Hutchinson Cancer Research Center, WA, Seattle, United States4 aut |
| 700 | 1 | a Prentice, Rossu Public Health Sciences Division, Fred Hutchinson Cancer Research Center, WA, Seattle, United States; Department of Biostatistics, University of Washington, WA, Seattle, United States4 aut |
| 700 | 1 | a Qu, Conghuiu Public Health Sciences Division, Fred Hutchinson Cancer Research Center, WA, Seattle, United States4 aut |
| 700 | 1 | a Bézieau, Stéphaneu Service de Génétique Médicale, Centre Hospitalier Universitaire Nantes, Nantes, France4 aut |
| 700 | 1 | a Tangen, Catherineu SWOG Statistical Center, Fred Hutchinson Cancer Research Center, WA, Seattle, United States4 aut |
| 700 | 1 | a Mardis, Elaineu Department of Pediatrics, Nationwide Children’s Hospital, The Steve and Cindy Rasmussen Institute for Genomic Medicine, OH, Columbus, United States4 aut |
| 700 | 1 | a Yamaji, Taikiu Division of Epidemiology, National Cancer Center Institute for Cancer Control, National Cancer Center, Tokyo, Japan4 aut |
| 700 | 1 | a Sawada, Norieu Division of Cohort Research, National Cancer Center Institute for Cancer Control, National Cancer Center, Tokyo, Japan4 aut |
| 700 | 1 | a Iwasaki, Motokiu Division of Epidemiology, National Cancer Center Institute for Cancer Control, National Cancer Center, Tokyo, Japan; Division of Cohort Research, National Cancer Center Institute for Cancer Control, National Cancer Center, Tokyo, Japan4 aut |
| 700 | 1 | a Haiman, Christopheru Department of Preventive Medicine, Center for Genetic Epidemiology, University of Southern California, CA, Los Angeles, United States4 aut |
| 700 | 1 | a Le Marchand, Loicu Cancer Center, University of Hawaii, HI, Honolulu, United States4 aut |
| 700 | 1 | a Wu, Annau Preventative Medicine, University of Southern California, CA, Los Angeles, United States4 aut |
| 700 | 1 | a Qu, Chenxuu USC Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, CA, Los Angeles, United States4 aut |
| 700 | 1 | a McNeil, Carolineu USC Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, CA, Los Angeles, United States4 aut |
| 700 | 1 | a Coetzee, Gerhardu Van Andel Research Institute, MI, Grand Rapids, United States4 aut |
| 700 | 1 | a Hayward, Carolineu MRC Human Genetics Unit, Institute of Genomics and Cancer, University of Edinburgh, Edinburgh, United Kingdom4 aut |
| 700 | 1 | a Deary, Ianu Lothian Birth Cohorts group, Department of Psychology, University of Edinburgh, Edinburgh, United Kingdom4 aut |
| 700 | 1 | a Harris, Sarahu Lothian Birth Cohorts group, Department of Psychology, University of Edinburgh, Edinburgh, United Kingdom4 aut |
| 700 | 1 | a Theodoratou, Evropiu Centre for Global Health, Usher Institute, University of Edinburgh, Edinburgh, United Kingdom4 aut |
| 700 | 1 | a Reid, Stuartu Colon Cancer Genetics Group, Medical Research Council Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, United Kingdom4 aut |
| 700 | 1 | a Walker, Marionu Colon Cancer Genetics Group, Medical Research Council Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, United Kingdom4 aut |
| 700 | 1 | a Ooi, Li Yinu Colon Cancer Genetics Group, Medical Research Council Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, United Kingdom; Department of Pathology, National University Hospital, National University Health System, Singapore, Singapore4 aut |
| 700 | 1 | a Moreno, Victoru Colorectal Cancer Group, ONCOBELL Program, Bellvitge Biomedical Research Institute, Barcelona, Spain; Oncology Data Analytics Program, Catalan Institute of Oncology, Barcelona, Spain; Consortium for Biomedical Research in Epidemiology and Public Health, Madrid, Madrid, Spain; Department of Clinical Sciences, Faculty of Medicine, University of Barcelona, Barcelona, Spain4 aut |
| 700 | 1 | a Casey, Grahamu Center for Public Health Genomics, Department of Public Health Sciences, University of Virginia, VA, Charlottesville, United States4 aut |
| 700 | 1 | a Gruber, Stephenu Department of Medical Oncology and Center For Precision Medicine, City of Hope National Medical Center, CA, Duarte, United States4 aut |
| 700 | 1 | a Tomlinson, Ianu Edinburgh Cancer Research Centre, Institute of Genomics and Cancer, University of Edinburgh, Edinburgh, United Kingdom; Institute of Cancer and Genomic Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom4 aut |
| 700 | 1 | a Zheng, Weiu Division of Epidemiology, Department of Medicine, Vanderbilt-Ingram Cancer Center, Vanderbilt Epidemiology Center, Vanderbilt University Medical Center, TN, Nashville, United States4 aut |
| 700 | 1 | a Dunlop, Malcolmu Colon Cancer Genetics Group, Medical Research Council Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, United Kingdom4 aut |
| 700 | 1 | a Houlston, Richardu Division of Genetics and Epidemiology, Institute of Cancer Research, London, United Kingdom4 aut |
| 700 | 1 | a Peters, Ulrikeu Public Health Sciences Division, Fred Hutchinson Cancer Research Center, WA, Seattle, United States; Department of Epidemiology, University of Washington, WA, Seattle, United States4 aut |
| 710 | 2 | a Edinburgh Cancer Research Centre, Institute of Genomics and Cancer, University of Edinburgh, Edinburgh, United Kingdom; Genomic Medicine Group, Instituto de Investigacion Sanitaria de Santiago, Santiago de Compostela, Spainb Colon Cancer Genetics Group, Medical Research Council Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, United Kingdom; Danish Institute for Advanced Study, Department of Public Health, University of Southern Denmark, Odense, Denmark4 org |
| 773 | 0 | t Nature Geneticsd : Nature Publishing Groupg 55, s. 89-99q 55<89-99x 1061-4036x 1546-1718 |
| 856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-202082 |
| 856 | 4 8 | u https://doi.org/10.1038/s41588-022-01222-9 |
| 856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:153345889 |
| 856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:151984045 |
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