Search: onr:"swepub:oai:DiVA.org:umu-71608" > Genome-wide meta-an...
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000 | 18857naa a2204381 4500 | |
001 | oai:DiVA.org:umu-71608 | |
003 | SwePub | |
008 | 130604s2013 | |||||||||||000 ||eng| | |
009 | oai:lup.lub.lu.se:0ed1c4df-424a-4149-9aa4-3ff244561c28 | |
009 | oai:DiVA.org:uu-200675 | |
009 | oai:prod.swepub.kib.ki.se:126660018 | |
009 | oai:gup.ub.gu.se/181095 | |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-716082 URI |
024 | 7 | a https://doi.org/10.1038/ng.26062 DOI |
024 | 7 | a https://lup.lub.lu.se/record/38434962 URI |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-2006752 URI |
024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:1266600182 URI |
024 | 7 | a https://gup.ub.gu.se/publication/1810952 URI |
040 | a (SwePub)umud (SwePub)lud (SwePub)uud (SwePub)kid (SwePub)gu | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Berndt, Sonja I.4 aut |
245 | 1 0 | a Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture |
264 | c 2013-04-07 | |
264 | 1 | b Springer Science and Business Media LLC,c 2013 |
338 | a print2 rdacarrier | |
520 | a Approaches exploiting trait distribution extremes may be used to identify loci associated with common traits, but it is unknown whether these loci are generalizable to the broader population. In a genome-wide search for loci associated with the upper versus the lower 5th percentiles of body mass index, height and waist-to-hip ratio, as well as clinical classes of obesity, including up to 263,407 individuals of European ancestry, we identified 4 new loci (IGFBP4, H6PD, RSRC1 and PPP2R2A) influencing height detected in the distribution tails and 7 new loci (HNF4G, RPTOR, GNAT2, MRPS33P4, ADCY9, HS6ST3 and ZZZ3) for clinical classes of obesity. Further, we find a large overlap in genetic structure and the distribution of variants between traits based on extremes and the general population and little etiological heterogeneity between obesity subgroups. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Medicinska och farmaceutiska grundvetenskaperx Medicinsk genetik0 (SwePub)301072 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Basic Medicinex Medical Genetics0 (SwePub)301072 hsv//eng |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Endokrinologi och diabetes0 (SwePub)302052 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Endocrinology and Diabetes0 (SwePub)302052 hsv//eng |
650 | 7 | a NATURVETENSKAPx Biologix Genetik0 (SwePub)106092 hsv//swe |
650 | 7 | a NATURAL SCIENCESx Biological Sciencesx Genetics0 (SwePub)106092 hsv//eng |
700 | 1 | a Gustafsson, Stefanu Uppsala universitet,Institutionen för medicinska vetenskaper,Science for Life Laboratory, SciLifeLab,Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden4 aut0 (Swepub:uu)stegu732 |
700 | 1 | a Maegi, Reedik4 aut |
700 | 1 | a Ganna, Andreau Karolinska Institutet4 aut |
700 | 1 | a Wheeler, Eleanor4 aut |
700 | 1 | a Feitosa, Mary F.4 aut |
700 | 1 | a Justice, Anne E.4 aut |
700 | 1 | a Lind, Larsu Uppsala universitet,Kardiovaskulär epidemiologi4 aut0 (Swepub:uu)larslind |
700 | 1 | a Croteau-Chonka, Damien C.4 aut |
700 | 1 | a Day, Felix R.4 aut |
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700 | 1 | a Fall, Tove,d 1979-u Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden4 aut0 (Swepub:uu)tovfa878 |
700 | 1 | a Ferreira, Teresa4 aut |
700 | 1 | a Gentilini, Davide4 aut |
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700 | 1 | a Johansson, Åsau Uppsala universitet,Genomik,Uppsala kliniska forskningscentrum (UCR)4 aut0 (Swepub:uu)asjoh108 |
700 | 1 | a Johnson, Toby4 aut |
700 | 1 | a Kanoni, Stavroula4 aut |
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700 | 1 | a Kristiansson, Katiu Karolinska Institutet4 aut |
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700 | 1 | a Lamina, Claudia4 aut |
700 | 1 | a Lecoeur, Cecile4 aut |
700 | 1 | a Li, Guo4 aut |
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700 | 1 | a Shungin, Dmitryu Lund University,Lunds universitet,Umeå universitet,Medicin,Genomik, diabetes och endokrinologi,Forskargrupper vid Lunds universitet,Genetisk och molekylär epidemiologi,Genomics, Diabetes and Endocrinology,Lund University Research Groups,Genetic and Molecular Epidemiology4 aut0 (Swepub:lu)med-dsn |
700 | 1 | a Smith, Albert Vernon4 aut |
700 | 1 | a Strawbridge, Rona J.u Karolinska Institutet4 aut |
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700 | 1 | a Vandenput, Liesbeth,d 1974u Gothenburg University,Göteborgs universitet,Centre for Bone and Arthritis Research,Institutionen för medicin, avdelningen för invärtesmedicin och klinisk nutrition,Institute of Medicine, Department of Internal Medicine and Clinical Nutrition4 aut0 (Swepub:gu)xvanli |
700 | 1 | a Waite, Lindsay L.4 aut |
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700 | 1 | a Asselbergs, Folkert W.4 aut |
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700 | 1 | a Franks, Paul W.u Lund University,Lunds universitet,Umeå universitet,Medicin,Genomik, diabetes och endokrinologi,Forskargrupper vid Lunds universitet,Genetisk och molekylär epidemiologi,Genomics, Diabetes and Endocrinology,Lund University Research Groups,Genetic and Molecular Epidemiology4 aut0 (Swepub:lu)med-plf |
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700 | 1 | a Groop, Leifu Lund University,Lunds universitet,Genomik, diabetes och endokrinologi,Forskargrupper vid Lunds universitet,Genomics, Diabetes and Endocrinology,Lund University Research Groups4 aut0 (Swepub:lu)endo-lgr |
700 | 1 | a Haritunian, Talin4 aut |
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700 | 1 | a Mohlke, Karen L.4 aut |
700 | 1 | a O'Connell, Jeffrey R.4 aut |
700 | 1 | a Pawitan, Yudiu Karolinska Institutet4 aut |
700 | 1 | a Schadt, Eric E.4 aut |
700 | 1 | a Schlessinger, David4 aut |
700 | 1 | a Steinthorsdottir, Valgerdur4 aut |
700 | 1 | a Strachan, David P.4 aut |
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700 | 1 | a Ingelsson, Erik,d 1975-u Uppsala universitet,Science for Life Laboratory, SciLifeLab,Molekylär epidemiologi,Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden;Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK;Genetics of Complex Traits, Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, UK4 aut0 (Swepub:uu)ering425 |
710 | 2 | a Uppsala universitetb Institutionen för medicinska vetenskaper4 org |
773 | 0 | t Nature Geneticsd : Springer Science and Business Media LLCg 45:5, s. 501-U69q 45:5<501-U69x 1061-4036x 1546-1718 |
856 | 4 | u https://irinsubria.uninsubria.it/bitstream/11383/1850142/1/ng.2606.pdf |
856 | 4 | u http://dx.doi.org/10.1038/ng.2606y FULLTEXT |
856 | 4 | u https://uu.diva-portal.org/smash/get/diva2:624801/FULLTEXT02.pdfx primaryx Raw objecty fulltext:postprint |
856 | 4 | u https://uu.diva-portal.org/smash/get/diva2:624801/ATTACHMENT01.pdfy attachment:postprint |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-71608 |
856 | 4 8 | u https://doi.org/10.1038/ng.2606 |
856 | 4 8 | u https://lup.lub.lu.se/record/3843496 |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-200675 |
856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:126660018 |
856 | 4 8 | u https://gup.ub.gu.se/publication/181095 |
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