Sökning: onr:"swepub:oai:DiVA.org:umu-95868" > Development and opt...
Fältnamn | Indikatorer | Metadata |
---|---|---|
000 | 02478naa a2200373 4500 | |
001 | oai:DiVA.org:umu-95868 | |
003 | SwePub | |
008 | 141106s2014 | |||||||||||000 ||eng| | |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-958682 URI |
024 | 7 | a https://doi.org/10.1002/ejoc.2014026842 DOI |
040 | a (SwePub)umu | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Kindahl, Tomasu Umeå universitet,Kemiska institutionen4 aut0 (Swepub:umu)toskil02 |
245 | 1 0 | a Development and optimization of simple one-step methods for the synthesis of 4-amino-substituted 1,8-naphthalimides |
264 | c 2014-08-20 | |
264 | 1 | b Wiley,c 2014 |
338 | a print2 rdacarrier | |
520 | a The 1,8-naphthalimide central fragment can be found in a vast number of bioactive compounds and drugs in clinical trials, and can be recognized from their use as fluorescent probes. Of key importance for the fluorescent properties of the scaffold is the 4-amino substituent, which has also proven to be critical in several other chemical and biological applications. Because of the great interest in 1,8-naphthalimides in general, and 4-amino-substituted 1,8-naphthalimides in particular, we have developed and optimized one-step procedures with which to access these derivatives by using an experimental design approach. The multivariate studies of temperature, reaction time, and equivalents of substrates identified conditions with close to quantitative yields that could be applied to generate a range of 4-amino-substituted 1,8-naphthalimides in high yields. | |
650 | 7 | a NATURVETENSKAPx Kemix Organisk kemi0 (SwePub)104052 hsv//swe |
650 | 7 | a NATURAL SCIENCESx Chemical Sciencesx Organic Chemistry0 (SwePub)104052 hsv//eng |
653 | a Oxygen heterocycles | |
653 | a Multicomponent reactions | |
653 | a Nitrogen heterocycles | |
653 | a Synthetic methods | |
653 | a crowave chemistry | |
700 | 1 | a Chorell, Elinu Umeå universitet,Medicin4 aut0 (Swepub:umu)elnpon01 |
700 | 1 | a Chorell, Eriku Umeå universitet,Kemiska institutionen4 aut0 (Swepub:umu)erkchl00 |
710 | 2 | a Umeå universitetb Kemiska institutionen4 org |
773 | 0 | t European Journal of Organic Chemistryd : Wileyg :28, s. 6175-6182q :28<6175-6182x 1434-193Xx 1099-0690 |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-95868 |
856 | 4 8 | u https://doi.org/10.1002/ejoc.201402684 |
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