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| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 03598naa a2200565 4500 | |
| 001 | oai:DiVA.org:uu-107252 | |
| 003 | SwePub | |
| 008 | 090730s2016 | |||||||||||000 ||eng| | |
| 009 | oai:DiVA.org:kth-190685 | |
| 024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-1072522 URI |
| 024 | 7 | a https://doi.org/10.1039/c6an00735j2 DOI |
| 024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-1906852 URI |
| 040 | a (SwePub)uud (SwePub)kth | |
| 041 | a engb eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a ref2 swepub-contenttype |
| 072 | 7 | a art2 swepub-publicationtype |
| 100 | 1 | a Duner, Gunnaru KTH,Yt- och korrosionsvetenskap,Department of Chemistry, KTH4 aut0 (Swepub:kth)u1dihqph |
| 245 | 1 0 | a Signal Enhancement in Ligand-Receptor Interactions using Dynamic Polymers at Quartz Crystal Microbalance Surfaces |
| 264 | c 2016 | |
| 264 | 1 | b Royal Society of Chemistry (RSC),c 2016 |
| 338 | a electronic2 rdacarrier | |
| 500 | a QC 20160815 | |
| 520 | a The potential for signal amplification on QCM sensors by use of in situ polymerized poly(acrylic acid) brushes has been studied. A biotin derivative was immobilized on these surfaces and the interaction with anti-biotin Fabs was evaluated. Interaction data was found to be specific for the studied binding events, and the level of non-specific binding was shown to be low. The surface was proven to be suitable for regeneration, of importance for biomolecular interaction analysis and repetitive immunoassays.For comparison, the same interaction system was tested using commercial sensor surfaces with carboxylated self-assembled monolayers. The poly(acrylic acid) surface showed a dramatic increase in signal response with more than ten times the signal of the carboxylated self-assembled monolayer surface. Thus, the present study shows that polymers can be successfully applied to amplify responses on QCM sensors, valuable for studies of interactions between receptors and low molecular weight compounds. | |
| 650 | 7 | a NATURVETENSKAPx Kemix Polymerkemi0 (SwePub)104062 hsv//swe |
| 650 | 7 | a NATURAL SCIENCESx Chemical Sciencesx Polymer Chemistry0 (SwePub)104062 hsv//eng |
| 650 | 7 | a NATURVETENSKAPx Kemix Organisk kemi0 (SwePub)104052 hsv//swe |
| 650 | 7 | a NATURAL SCIENCESx Chemical Sciencesx Organic Chemistry0 (SwePub)104052 hsv//eng |
| 653 | a dynamic chemistry | |
| 653 | a quartz crystal microbalance | |
| 653 | a iniferter | |
| 653 | a photopolymerization | |
| 653 | a biosensor | |
| 653 | a interaction | |
| 653 | a Polymer chemistry | |
| 653 | a Polymerkemi | |
| 653 | a Ytbioteknik | |
| 653 | a Surface Biotechnology | |
| 700 | 1 | a Anderson, Henriku Uppsala universitet,Fasta tillståndets elektronik,Attana AB,Thin Films Group4 aut0 (Swepub:uu)henan442 |
| 700 | 1 | a Pei, Zhichaou Attana AB4 aut |
| 700 | 1 | a Ingemarsson, Björnu Attana AB4 aut |
| 700 | 1 | a Aastrup, Teodoru Attana AB4 aut |
| 700 | 1 | a Ramstrom, Olofu KTH,Organisk kemi,Department of Chemistry, KTH4 aut0 (Swepub:kth)u1aj7snf |
| 710 | 2 | a KTHb Yt- och korrosionsvetenskap4 org |
| 773 | 0 | t The Analystd : Royal Society of Chemistry (RSC)g 141:13, s. 3993-3996q 141:13<3993-3996x 0003-2654x 1364-5528 |
| 856 | 4 | u https://uu.diva-portal.org/smash/get/diva2:228401/FULLTEXT01.pdfx primaryx Raw objecty fulltext:print |
| 856 | 4 | u https://pubs.rsc.org/en/content/articlepdf/2016/an/c6an00735j |
| 856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-107252 |
| 856 | 4 8 | u https://doi.org/10.1039/c6an00735j |
| 856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-190685 |
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