onr:"swepub:oai:DiVA.org:uu-108245"
Sökning: onr:"swepub:oai:DiVA.org:uu-108245" > Analysis of the DNA...
- 1 av 1
- Föregående post
- Nästa post
- Till träfflistan
| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 06556naa a2201153 4500 | |
| 001 | oai:DiVA.org:uu-108245 | |
| 003 | SwePub | |
| 008 | 090909s2006 | |||||||||||000 ||eng| | |
| 024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-1082452 URI |
| 024 | 7 | a https://doi.org/10.1038/nature046012 DOI |
| 040 | a (SwePub)uu | |
| 041 | a engb eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a ref2 swepub-contenttype |
| 072 | 7 | a art2 swepub-publicationtype |
| 100 | 1 | a Zody, Michael,d 1968-u Broad Institute4 aut0 (Swepub:uu)miczo266 |
| 245 | 1 0 | a Analysis of the DNA sequence and duplication history of human chromosome 15 |
| 264 | 1 | b Springer Science and Business Media LLC,c 2006 |
| 338 | a print2 rdacarrier | |
| 520 | a Here we present a finished sequence of human chromosome 15, together with a high-quality gene catalogue. As chromosome 15 is one of seven human chromosomes with a high rate of segmental duplication, we have carried out a detailed analysis of the duplication structure of the chromosome. Segmental duplication in chromosome 15 are largely clustered in two regions, on proximal and distal 15q; the proximal region is notable because recombination among the segmental duplications can result in deletions causing Prader-Willi and Angelman syndromes. Sequence analysis shows that the proximal and distal regions of 15q share extensive ancient similarity. Using a simple approach, we have been able to reconstruct many of the events by which the current duplication structure arose. We find that most of the intrachromosomal duplications seem to share a common ancestry. Finally, we demonstrate that some remaining gaps in the genome sequence are probably due to structural polymorphisms between haplotypes; this may explain a significant fraction of the gaps remaining in the human genome. | |
| 650 | 7 | a NATURVETENSKAPx Biologix Genetik0 (SwePub)106092 hsv//swe |
| 650 | 7 | a NATURAL SCIENCESx Biological Sciencesx Genetics0 (SwePub)106092 hsv//eng |
| 653 | a Genetics | |
| 653 | a Genetik | |
| 653 | a Genetics | |
| 653 | a Genetik | |
| 700 | 1 | a Garber, Manuelu Broad Institute4 aut |
| 700 | 1 | a Sharpe, Tedu Broad Institute4 aut |
| 700 | 1 | a Young, Sarahu Broad Institute4 aut |
| 700 | 1 | a Rowen, Leeu Institute for Systems Biology4 aut |
| 700 | 1 | a O'Neill, Keithu Broad Institute4 aut |
| 700 | 1 | a Whittaker, Charlesu Broad Institute4 aut |
| 700 | 1 | a Kamal, Michaelu Broad Institute4 aut |
| 700 | 1 | a Chang, Jeanu Broad Institute4 aut |
| 700 | 1 | a Cuomo, Christinau Broad Institute4 aut |
| 700 | 1 | a Dewar, Kenu Broad Institute4 aut |
| 700 | 1 | a FitzGerald, Michaelu Broad Institute4 aut |
| 700 | 1 | a Kodira, Chinnappau Broad Institute4 aut |
| 700 | 1 | a Madan, Anupu Institute for Systems Biology4 aut |
| 700 | 1 | a Qin, Shizhenu Institute for Systems Biology4 aut |
| 700 | 1 | a Yang, Xiaopingu Broad Institute4 aut |
| 700 | 1 | a Abbasi, Nissau Institute for Systems Biology4 aut |
| 700 | 1 | a Abouelleil, Amru Broad Institute4 aut |
| 700 | 1 | a Arachchi, Harindrau Broad Institute4 aut |
| 700 | 1 | a Baradarani, Lidau Institute for Systems Biology4 aut |
| 700 | 1 | a Birditt, Brianu Institute for Systems Biology4 aut |
| 700 | 1 | a Bloom, Scottu Institute for Systems Biology4 aut |
| 700 | 1 | a Bloom, Tobyu Broad Institute4 aut |
| 700 | 1 | a Borowsky, Marku Broad Institute4 aut |
| 700 | 1 | a Burke, Jeremyu Institute for Systems Biology4 aut |
| 700 | 1 | a Butler, Jonathanu Broad Institute4 aut |
| 700 | 1 | a Cook, Aprilu Broad Institute4 aut |
| 700 | 1 | a DeArellano, Kurtu Broad Institute4 aut |
| 700 | 1 | a DeCaprio, Davidu Broad Institute4 aut |
| 700 | 1 | a Dorris, Lesteru Broad Institute4 aut |
| 700 | 1 | a Dors, Monicau Institute for Systems Biology4 aut |
| 700 | 1 | a Eichler, Evanu University of Washington, Department of Genome Sciences4 aut |
| 700 | 1 | a Engels, Reinhardu Broad Institute4 aut |
| 700 | 1 | a Fahey, Jessicau Institute for Systems Biology4 aut |
| 700 | 1 | a Fleetwood, Peteru Institute for Systems Biology4 aut |
| 700 | 1 | a Friedman, Cynthiau Fred Hutchinson Cancer Research Center, Division of Human Biology4 aut |
| 700 | 1 | a Gearin, Garyu Broad Institute4 aut |
| 700 | 1 | a Hall, Jenniferu Broad Institute4 aut |
| 700 | 1 | a Hensley, Graceu Institute for Systems Biology4 aut |
| 700 | 1 | a Johnson, Erickau Institute for Systems Biology4 aut |
| 700 | 1 | a Jones, Charlienu Broad Institute4 aut |
| 700 | 1 | a Kamat, Ashau Broad Institute4 aut |
| 700 | 1 | a Kaur, Amardeepu Institute for Systems Biology4 aut |
| 700 | 1 | a Locke, Devinu University of Washington, Department of Genome Sciences4 aut |
| 700 | 1 | a Madan, Anuradhau Institute for Systems Biology4 aut |
| 700 | 1 | a Munson, Glenu Broad Institute4 aut |
| 700 | 1 | a Jaffe, Davidu Broad Institute4 aut |
| 700 | 1 | a Lui, Annieu Broad Institute4 aut |
| 700 | 1 | a Macdonald, Pendexteru Broad Institute4 aut |
| 700 | 1 | a Mauceli, Evanu Broad Institute4 aut |
| 700 | 1 | a Naylor, Jeromeu Broad Institute4 aut |
| 700 | 1 | a Nesbitt, Ryanu Institute for Systems Biology4 aut |
| 700 | 1 | a Nicol, Robertu Broad Institute4 aut |
| 700 | 1 | a O'Leary, Sinéadu Broad Institute4 aut |
| 700 | 1 | a Ratcliffe, Amberu Institute for Systems Biology4 aut |
| 700 | 1 | a Rounsley, Stevenu Broad Institute4 aut |
| 700 | 1 | a She, Xinweiu University of Washington, Department of Genome Sciences4 aut |
| 700 | 1 | a Sneddon, Katherineu University College London, Department of Biology,HUGO Gene Nomenclature Committee4 aut |
| 700 | 1 | a Stewart, Sandrau Institute for Systems Biology4 aut |
| 700 | 1 | a Sougnez, Carrieu Broad Institute4 aut |
| 700 | 1 | a Stone, Sabrinau Broad Institute4 aut |
| 700 | 1 | a Topham, Kerriu Broad Institute4 aut |
| 700 | 1 | a Vincent, Dascenau Institute for Systems Biology4 aut |
| 700 | 1 | a Wang, Shunguangu Broad Institute4 aut |
| 700 | 1 | a Zimmer, Andrewu Broad Institute4 aut |
| 700 | 1 | a Birren, Bruceu Broad Institute4 aut |
| 700 | 1 | a Hood, Leroyu Institute for Systems Biology4 aut |
| 700 | 1 | a Lander, icu Broad Institute4 aut |
| 700 | 1 | a Nusbaum, Chadu Broad Institute4 aut |
| 710 | 2 | a Broad Instituteb Institute for Systems Biology4 org |
| 773 | 0 | t Natured : Springer Science and Business Media LLCg 440:7084, s. 671-675q 440:7084<671-675x 0028-0836x 1476-4687 |
| 856 | 4 | u https://www.nature.com/articles/nature04601.pdf |
| 856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-108245 |
| 856 | 4 8 | u https://doi.org/10.1038/nature04601 |
- 1 av 1
- Föregående post
- Nästa post
- Till träfflistan
Hitta mer i SwePub
- Av författaren/redakt...
- Zody, Michael, 1 ...
- Garber, Manuel
- Sharpe, Ted
- Young, Sarah
- Rowen, Lee
- O'Neill, Keith
- visa fler...
- Whittaker, Charl ...
- Kamal, Michael
- Chang, Jean
- Cuomo, Christina
- Dewar, Ken
- FitzGerald, Mich ...
- Kodira, Chinnapp ...
- Madan, Anup
- Qin, Shizhen
- Yang, Xiaoping
- Abbasi, Nissa
- Abouelleil, Amr
- Arachchi, Harind ...
- Baradarani, Lida
- Birditt, Brian
- Bloom, Scott
- Bloom, Toby
- Borowsky, Mark
- Burke, Jeremy
- Butler, Jonathan
- Cook, April
- DeArellano, Kurt
- DeCaprio, David
- Dorris, Lester
- Dors, Monica
- Eichler, Evan
- Engels, Reinhard
- Fahey, Jessica
- Fleetwood, Peter
- Friedman, Cynthi ...
- Gearin, Gary
- Hall, Jennifer
- Hensley, Grace
- Johnson, Ericka
- Jones, Charlien
- Kamat, Asha
- Kaur, Amardeep
- Locke, Devin
- Madan, Anuradha
- Munson, Glen
- Jaffe, David
- Lui, Annie
- Macdonald, Pende ...
- Mauceli, Evan
- Naylor, Jerome
- Nesbitt, Ryan
- Nicol, Robert
- O'Leary, Sinéad
- Ratcliffe, Amber
- Rounsley, Steven
- She, Xinwei
- Sneddon, Katheri ...
- Stewart, Sandra
- Sougnez, Carrie
- Stone, Sabrina
- Topham, Kerri
- Vincent, Dascena
- Wang, Shunguang
- Zimmer, Andrew
- Birren, Bruce
- Hood, Leroy
- Lander, ic
- Nusbaum, Chad
- visa färre...
- Om ämnet
-
- NATURVETENSKAP
- NATURVETENSKAP
- och Biologi
- och Genetik
- Artiklar i publikationen
- Nature
- Av lärosätet
- Uppsala universitet
Sök utanför SwePub
- Sök vidare i:
- Google Book Search
- Google Scholar
Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.
- Copyright © LIBRIS - Nationella bibliotekssystem
- LIBRIS.kb.se
