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Sökning: onr:"swepub:oai:DiVA.org:uu-162884" > Cdv-based cell divi...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00003138naa a2200361 4500
001oai:DiVA.org:uu-162884
003SwePub
008111205s2011 | |||||||||||000 ||eng|
024a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-1628842 URI
024a https://doi.org/10.1111/j.1365-2958.2011.07834.x2 DOI
040 a (SwePub)uu
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
100a Pelve, Erik A.,d 1980-u Uppsala universitet,Molekylär evolution4 aut0 (Swepub:uu)erkar473
2451 0a Cdv-based cell division and cell cycle organization in the thaumarchaeon Nitrosopumilus maritimus
264 c 2011-09-30
264 1b Wiley,c 2011
338 a print2 rdacarrier
520 a Cell division is mediated by different mechanisms in different evolutionary lineages. While bacteria and euryarchaea utilize an FtsZ-based mechanism, most crenarchaea divide using the Cdv system, related to the eukaryotic ESCRT-III machinery. Intriguingly, thaumarchaeal genomes encode both FtsZ and Cdv protein homologues, raising the question of their division mode. Here, we provide evidence indicating that Cdv is the primary division system in the thaumarchaeon Nitrosopumilus maritimus. We also show that the cell cycle is differently organized as compared to hyperthermophilic crenarchaea, with a longer pre-replication phase and a shorter post-replication stage. In particular, the time required for chromosome replication is remarkably extensive, 15-18 h, indicating a low replication rate. Further, replication did not continue to termination in a significant fraction of N. maritimus cell populations following substrate depletion. Both the low replication speed and the propensity for replication arrest are likely to represent adaptations to extremely oligotrophic environments. The results demonstrate that thaumarchaea, crenarchaea and euryarchaea display differences not only regarding phylogenetic affiliations and gene content, but also in fundamental cellular and physiological characteristics. The findings also have implications for evolutionary issues concerning the last archaeal common ancestor and the relationship between archaea and eukaryotes.
650 7a NATURVETENSKAPx Biologix Mikrobiologi0 (SwePub)106062 hsv//swe
650 7a NATURAL SCIENCESx Biological Sciencesx Microbiology0 (SwePub)106062 hsv//eng
700a Lindås, Ann-Christinu Uppsala universitet,Molekylär evolution4 aut0 (Swepub:uu)liann020
700a Martens-Habbena, Willm4 aut
700a de la Torre, José R.4 aut
700a Stahl, David A.4 aut
700a Bernander, Rolfu Uppsala universitet,Molekylär evolution4 aut0 (Swepub:uu)rbe03860
710a Uppsala universitetb Molekylär evolution4 org
773t Molecular Microbiologyd : Wileyg 82:3, s. 555-566q 82:3<555-566x 0950-382Xx 1365-2958
856u https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1365-2958.2011.07834.x
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-162884
8564 8u https://doi.org/10.1111/j.1365-2958.2011.07834.x

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