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LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00003776naa a2200541 4500
001oai:DiVA.org:uu-177584
003SwePub
008120716s2012 | |||||||||||000 ||eng|
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-1775842 URI
0247 a https://doi.org/10.1136/thoraxjnl-2011-2012492 DOI
040 a (SwePub)uu
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
1001 a Leynaert, Benedicte4 aut
2451 0a Gender differences in prevalence, diagnosis and incidence of allergic and non-allergic asthma :b a population-based cohort
264 c 2012-02-14
264 1b BMJ,c 2012
338 a print2 rdacarrier
520 a Background Although women with severe non-allergic asthma may represent a substantial proportion of adults with asthma in clinical practice, gender differences in the incidence of allergic and non-allergic asthma have been little investigated in the general population. Methods Gender differences in asthma prevalence, reported diagnosis and incidence were investigated in 9091 men and women randomly selected from the general population and followed up after 8-10 years as part of the European Community Respiratory Health Survey. The protocol included assessment of bronchial responsiveness, IgE specific to four common allergens and skin tests to nine allergens. Results Asthma was 20% more frequent in women than in men over the age of 35 years. Possible under-diagnosis of asthma appeared to be particularly frequent among non-atopic individuals, but was as frequent in women as in men. The follow-up of subjects without asthma at baseline showed a higher incidence of asthma in women than in men (HR 1.94; 95% CI 1.40 to 2.68), which was not explained by differences in smoking, obesity or lung function. More than 60% of women and 30% of men with new-onset asthma were non-atopic. The incidence of non-allergic asthma was higher in women than in men throughout all the reproductive years (HR 3.51; 95% CI 2.21 to 5.58), whereas no gender difference was observed for the incidence of allergic asthma. Conclusions This study shows that female sex is an independent risk factor for non-allergic asthma, and stresses the need for more careful assessment of possible non-allergic asthma in clinical practice, in men and women.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Lungmedicin och allergi0 (SwePub)302192 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Respiratory Medicine and Allergy0 (SwePub)302192 hsv//eng
7001 a Sunyer, Jordi4 aut
7001 a Garcia-Esteban, Raquel4 aut
7001 a Svanes, Cecilie4 aut
7001 a Jarvis, Deborah4 aut
7001 a Cerveri, Isa4 aut
7001 a Dratva, Julia4 aut
7001 a Gislason, Thorarinn4 aut
7001 a Heinrich, Joachim4 aut
7001 a Janson, Christeru Uppsala universitet,Lungmedicin och allergologi4 aut0 (Swepub:uu)chrisjn
7001 a Kuenzli, Nino4 aut
7001 a de Marco, Roberto4 aut
7001 a Omenaas, Ernst4 aut
7001 a Raherison, Chantal4 aut
7001 a Gomez Real, Francisco4 aut
7001 a Wjst, Matthias4 aut
7001 a Zemp, Elisabeth4 aut
7001 a Zureik, Mahmoud4 aut
7001 a Burney, Peter G. J.4 aut
7001 a Anto, Josep M.4 aut
7001 a Neukirch, Francoise4 aut
7102 a Uppsala universitetb Lungmedicin och allergologi4 org
7730 t Thoraxd : BMJg 67:7, s. 625-631q 67:7<625-631x 0040-6376x 1468-3296
8564 u https://thorax.bmj.com/content/thoraxjnl/67/7/625.full.pdf
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-177584
8564 8u https://doi.org/10.1136/thoraxjnl-2011-201249

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