Search: onr:"swepub:oai:DiVA.org:uu-224340" > Plasma alkylresorci...
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000 | 06150naa a2200721 4500 | |
001 | oai:DiVA.org:uu-224340 | |
003 | SwePub | |
008 | 140509s2014 | |||||||||||000 ||eng| | |
009 | oai:slubar.slu.se:66813 | |
009 | oai:lup.lub.lu.se:e11f1ce7-0d60-42d6-8d10-9eb36a449d87 | |
009 | oai:prod.swepub.kib.ki.se:128602410 | |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-2243402 URI |
024 | 7 | a https://doi.org/10.1038/ejcn.2014.122 DOI |
024 | 7 | a https://res.slu.se/id/publ/668132 URI |
024 | 7 | a https://lup.lub.lu.se/record/43344772 URI |
024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:1286024102 URI |
040 | a (SwePub)uud (SwePub)slud (SwePub)lud (SwePub)ki | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Magnusdottir, O. K.4 aut |
245 | 1 0 | a Plasma alkylresorcinols C17:0/C21:0 ratio, a biomarker of relative whole-grain rye intake, is associated to insulin sensitivity :b a randomized study |
264 | c 2014-02-19 | |
264 | 1 | b Springer Science and Business Media LLC,c 2014 |
338 | a print2 rdacarrier | |
520 | a BACKGROUND/OBJECTIVES: Few studies have used biomarkers of whole-grain intake to study its relation to glucose metabolism. We aimed to investigate the association between plasma alkylresorcinols (AR), a biomarker of whole-grain rye and wheat intake, and glucose metabolism in individuals with metabolic syndrome (MetS). SUBJECTS/METHODS: Participants were 30-65 years of age, with body mass index 27-40 kg/m(2) and had MetS without diabetes. Individuals were recruited through six centers in the Nordic countries and randomized to a healthy Nordic diet (ND, n=96), rich in whole-grain rye and wheat, or a control diet (n=70), for 18-24 weeks. In addition, associations between total plasma AR concentration and C17:0/C21:0 homolog ratio as an indication of the relative whole-grain rye intake, and glucose metabolism measures from oral glucose tolerance tests were investigated in pooled (ND + control) regression analyses at 18/24 weeks. RESULTS: ND did not improve glucose metabolism compared with control diet, but the AR C17:0/C21:0 ratio was inversely associated with fasting insulin concentrations (P=0.002) and positively associated with the insulin sensitivity indices Matsuda ISI (P=0.026) and disposition index (P=0.022) in pooled analyses at 18/24 weeks, even after adjustment for confounders. The AR C17:0/C21:0 ratio was not significantly associated with insulin secretion indices. Total plasma AR concentration was not related to fasting plasma glucose or fasting insulin at 18/24 weeks. CONCLUSIONS: The AR C17:0/C21:0 ratio, an indicator of relative whole-grain rye intake, is associated with increased insulin sensitivity in a population with MetS. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Hälsovetenskapx Näringslära0 (SwePub)303042 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Health Sciencesx Nutrition and Dietetics0 (SwePub)303042 hsv//eng |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Annan klinisk medicin0 (SwePub)302992 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Other Clinical Medicine0 (SwePub)302992 hsv//eng |
653 | a alkylresorcinols | |
653 | a insulin sensitivity | |
653 | a whole grain | |
653 | a rye | |
700 | 1 | a Landberg, Rikardu Swedish University of Agricultural Sciences,Sveriges lantbruksuniversitet,Institutionen för livsmedelsvetenskap,Department of Food Science,Karolinska Institute4 aut0 (Swepub:slu)51036 |
700 | 1 | a Gunnarsdottir, I.4 aut |
700 | 1 | a Cloetens, Lu Lund University,Lunds universitet,Tillämpad biokemi,Centrum för tillämpade biovetenskaper,Kemiska institutionen,Institutioner vid LTH,Lunds Tekniska Högskola,Pure and Applied Biochemistry,Center for Applied Life Sciences,Department of Chemistry,Departments at LTH,Faculty of Engineering, LTH4 aut0 (Swepub:lu)tbio-lce |
700 | 1 | a Akesson, Bu Lund University,Lunds universitet,Tillämpad biokemi,Centrum för tillämpade biovetenskaper,Kemiska institutionen,Institutioner vid LTH,Lunds Tekniska Högskola,Pure and Applied Biochemistry,Center for Applied Life Sciences,Department of Chemistry,Departments at LTH,Faculty of Engineering, LTH,Skåne University Hospital4 aut0 (Swepub:lu)kc-bak |
700 | 1 | a Landin-Olsson, Monau Lund University,Lunds universitet,Medicin, Lund,Sektion II,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Medicine, Lund,Section II,Department of Clinical Sciences, Lund,Faculty of Medicine4 aut0 (Swepub:lu)med-mla |
700 | 1 | a Rosqvist, Fredriku Uppsala universitet,Klinisk nutrition och metabolism4 aut0 (Swepub:uu)frero353 |
700 | 1 | a Iggman, Davidu Uppsala universitet,Klinisk nutrition och metabolism4 aut0 (Swepub:uu)davig338 |
700 | 1 | a Schwab, U.4 aut |
700 | 1 | a Herzig, K-H4 aut |
700 | 1 | a Savolainen, M. J.4 aut |
700 | 1 | a Brader, L.4 aut |
700 | 1 | a Hermansen, K.4 aut |
700 | 1 | a Kolehmainen, M.4 aut |
700 | 1 | a Poutanen, K.4 aut |
700 | 1 | a Uusitupa, Mattiu Uppsala universitet,Klinisk nutrition och metabolism4 aut |
700 | 1 | a Thorsdottir, I.4 aut |
700 | 1 | a Risérus, Ulfu Uppsala universitet,Klinisk nutrition och metabolism4 aut0 (Swepub:uu)ulfriser |
710 | 2 | a Sveriges lantbruksuniversitetb Institutionen för livsmedelsvetenskap4 org |
710 | 2 | a Sveriges lantbruksuniversitet |
773 | 0 | t European Journal of Clinical Nutritiond : Springer Science and Business Media LLCg 68:4, s. 453-458q 68:4<453-458x 0954-3007x 1476-5640 |
856 | 4 | u https://www.nature.com/articles/ejcn201412.pdf |
856 | 4 | u http://www.ncbi.nlm.nih.gov/pubmed/24549027?dopt=Abstracty FULLTEXT |
856 | 4 | u http://dx.doi.org/10.1038/ejcn.2014.12y FULLTEXT |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-224340 |
856 | 4 8 | u https://doi.org/10.1038/ejcn.2014.12 |
856 | 4 8 | u https://res.slu.se/id/publ/66813 |
856 | 4 8 | u https://lup.lub.lu.se/record/4334477 |
856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:128602410 |
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