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Sökning: onr:"swepub:oai:DiVA.org:uu-265012" > Timing of percutane...

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FältnamnIndikatorerMetadata
00006188naa a2200589 4500
001oai:DiVA.org:uu-265012
003SwePub
008151020s2017 | |||||||||||000 ||eng|
009oai:DiVA.org:oru-64832
009oai:DiVA.org:liu-145039
009oai:prod.swepub.kib.ki.se:228927193
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-2650122 URI
0247 a https://doi.org/10.1093/ehjqcco/qcw0442 DOI
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-648322 URI
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-1450392 URI
0247 a http://kipublications.ki.se/Default.aspx?queryparsed=id:2289271932 URI
040 a (SwePub)uud (SwePub)orud (SwePub)liud (SwePub)ki
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
1001 a Lindholm, Danielu Uppsala universitet,Kardiologi,Uppsala kliniska forskningscentrum (UCR),Department of Medical Sciences, Cardiology, Uppsala University, Uppsala, Sweden; Uppsala Clinical Research Center, Dag Hammarskjölds väg 14B, 1 tr, SE-752 37 Uppsala, Sweden4 aut0 (Swepub:uu)danli945
2451 0a Timing of percutaneous coronary intervention in patients with non-ST-elevation myocardial infarction :b a SWEDEHEART study
264 c 2016-08-28
264 1b Oxford University Press,c 2017
338 a print2 rdacarrier
500 a Funding Agency:AstraZeneca within the Externally Sponsored Research Programme  ESR-14-10720
520 a AimsAlthough routine invasive management is recommended in NSTEMI patients, the optimal timing of the procedure is not defined. The aim of this study was to assess outcomes in relation to timing of PCI in NSTEMI patients.Methods and resultsThis was an observational, prospective, multicentre cohort study from the SWEDEHEART registry including all Swedish PCI centres. We included 40 494 consecutive PCI-treated patients who were admitted to any coronary care unit from 2006 to 2013. The primary outcome was all-cause death, and secondary outcomes were recurrent myocardial infarction (MI), stent thrombosis, and severe in-hospital bleeding. Outcomes were assessed within 1 year from admission in relation to pre-specified cut-offs to define early PCI: within 1, 2, or 3 days. Patients who received delayed PCI, compared with those who did not, were older, and had a higher prevalence of comorbidities (hypertension, hyperlipidaemia, diabetes, and prior stroke) but showed similar angiographic findings. Cox mixed-effects models showed a lower risk of all-cause death with early PCI across all three cut-offs: HR (95% CI) of 0.88 (0.80–0.98), 0.78 (0.71–0.86), and 0.75 (0.68–0.84), for the 1-, 2-, and 3-day cut-offs, respectively. Early PCI was associated with lower risk of recurrent MI for the 2- and 3-day cut-offs, but not for the 1-day cut-off. The reported rates of severe in-hospital bleeding were low, but tended to be higher in patients receiving delayed PCI.ConclusionIn patients undergoing PCI for NSTEMI, early invasive treatment is associated with lower risk of ischaemic outcomes.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Kardiologi0 (SwePub)302062 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cardiac and Cardiovascular Systems0 (SwePub)302062 hsv//eng
653 a cardiology
653 a acute coronary syndromes
653 a non-st-elevation myocardial infarction
653 a percutaneous coronary intervention
653 a timing
7001 a Alfredsson, Joakim,d 1962-u Linköpings universitet,Avdelningen för kardiovaskulär medicin,Medicinska fakulteten,Region Östergötland, Kardiologiska kliniken US4 aut0 (Swepub:liu)joaal38
7001 a Angerås, Oskaru Sahlgrens Univ Hosp, Dept Cardiol, Gothenburg, Sweden,Department of Cardiology, Sahlgrenska University Hospital, Gothenburg, Sweden4 aut
7001 a Böhm, Felixu Karolinska Institutet4 aut
7001 a Calais, Fredrik,d 1971-u Örebro universitet,Institutionen för medicinska vetenskaper,Department of Cardiology, Faculty of Health and Medical Sciences, Örebro University, Örebro, Sweden,Orebro Univ, Dept Cardiol, Fac Hlth, Orebro, Sweden4 aut0 (Swepub:oru)fcs
7001 a Koul, Sashau Lund Univ, Dept Cardiol, Clin Sci, Lund, Sweden,Department of Cardiology, Clinical Sciences, Lund University, Lund, Sweden4 aut
7001 a Lagerqvist, Bou Uppsala universitet,Kardiologi,Uppsala kliniska forskningscentrum (UCR),Department of Medical Sciences, Cardiology, Uppsala University, Uppsala, Sweden; Uppsala Clinical Research Center, Dag Hammarskjölds väg 14B, 1 tr, SE-752 37 Uppsala, Sweden4 aut0 (Swepub:uu)bolager
7001 a Renlund, Henriku Uppsala universitet,Uppsala kliniska forskningscentrum (UCR),Uppsala Clinical Research Center, Dag Hammarskjölds väg 14B, 1 tr, SE-752 37 Uppsala, Sweden4 aut0 (Swepub:uu)henre358
7001 a Sarno, Giovannau Uppsala universitet,Kardiologi,Uppsala kliniska forskningscentrum (UCR),Department of Medical Sciences, Cardiology, Uppsala University, Uppsala, Sweden; Uppsala Clinical Research Center, Dag Hammarskjölds väg 14B, 1 tr, SE-752 37 Uppsala, Sweden4 aut0 (Swepub:uu)giosa853
7001 a Varenhorst, Christophu Uppsala universitet,Kardiologi,Uppsala kliniska forskningscentrum (UCR),Department of Medical Sciences, Cardiology, Uppsala University, Uppsala, Sweden; Uppsala Clinical Research Center, Dag Hammarskjölds väg 14B, 1 tr, SE-752 37 Uppsala, Sweden4 aut0 (Swepub:uu)chrva923
7102 a Uppsala universitetb Kardiologi4 org
7730 t European Heart Journal - Quality of Care and Clinical Outcomesd : Oxford University Pressg 3:1, s. 53-60q 3:1<53-60x 2058-5225x 2058-1742
8564 u https://academic.oup.com/ehjqcco/article-pdf/3/1/53/9608046/qcw044.pdf
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-265012
8564 8u https://doi.org/10.1093/ehjqcco/qcw044
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-64832
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-145039
8564 8u http://kipublications.ki.se/Default.aspx?queryparsed=id:228927193

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