Sökning: onr:"swepub:oai:DiVA.org:uu-294337" > Effect of Breed on ...
Fältnamn | Indikatorer | Metadata |
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000 | 06593naa a2200685 4500 | |
001 | oai:DiVA.org:uu-294337 | |
003 | SwePub | |
008 | 160518s2016 | |||||||||||000 ||eng| | |
009 | oai:slubar.slu.se:79901 | |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-2943372 URI |
024 | 7 | a https://doi.org/10.1111/jvim.138292 DOI |
024 | 7 | a https://res.slu.se/id/publ/799012 URI |
040 | a (SwePub)uud (SwePub)slu | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Höglund, Katjau Swedish University of Agricultural Sciences,Sveriges lantbruksuniversitet,Institutionen för anatomi, fysiologi och biokemi,Department of Anatomy, Physiology and Biochemistry (AFB)4 aut0 (Swepub:slu)48365 |
245 | 1 0 | a Effect of Breed on Plasma Endothelin-1 Concentration, Plasma Renin Activity, and Serum Cortisol Concentration in Healthy Dogs |
264 | c 2016-01-27 | |
264 | 1 | b Wiley,c 2016 |
338 | a electronic2 rdacarrier | |
520 | a Background: There are breed differences in several blood variables in healthy dogs.Objective: Investigate breed variation in plasma endothelin-1 (ET-1) concentration, plasma renin activity, and serum cortisol concentration.Animals: Five-hundred and thirty-one healthy dogs of 9 breeds examined at 5 centers (2-4 breeds/center).Methods: Prospective observational study. Circulating concentrations of ET-1 and cortisol, and renin activity, were measured using commercially available assays. Absence of organ-related or systemic disease was ensured by thorough clinical investigations, including blood pressure measurement, echocardiography, ECG, blood and urine analysis.Results: Median ET-1 concentration was 1.29 (interquartile range [IQR], 0.97-1.82) pg/mL, median cortisol concentration 46.0 (IQR, 29.0-80.8) nmol/L, and median renin activity 0.73 (IQR, 0.48-1.10) ng/mL/h in all dogs. Overall, breed differences were found in ET-1 and cortisol concentrations, and renin activity (P < .0001 for all). Pair-wise comparisons between breeds differed in 67% of comparisons for ET-1, 22% for cortisol, and 19% for renin activity, respectively. Within centers, breed differences were found at 5/5 centers for ET-1, 4/5 centers for cortisol, and 2/5 centers for renin activity. Newfoundlands had highest median ET-1 concentration, 3 times higher than Cavalier King Charles Spaniels, Doberman Pinschers, and Dachshunds. Median renin activity was highest in Dachshunds, twice the median value in Newfoundlands and Boxers. Median cortisol concentration was highest in Finnish Lapphunds, almost 3 times higher than in Boxers.Conclusions and Clinical Importance: Breed variation might be important to take into consideration when interpreting test results in clinical studies. | |
650 | 7 | a LANTBRUKSVETENSKAPERx Veterinärmedicin0 (SwePub)4032 hsv//swe |
650 | 7 | a AGRICULTURAL SCIENCESx Veterinary Science0 (SwePub)4032 hsv//eng |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Kardiologi0 (SwePub)302062 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cardiac and Cardiovascular Systems0 (SwePub)302062 hsv//eng |
653 | a Biomarker | |
653 | a Breed variation | |
653 | a Canine | |
653 | a Vasoactive | |
700 | 1 | a Lequarre, A. -S4 aut |
700 | 1 | a Ljungvall, Ingridu Swedish University of Agricultural Sciences,Sveriges lantbruksuniversitet,Institutionen för kliniska vetenskaper (KV),Department of Clinical Sciences4 aut0 (Swepub:slu)48949 |
700 | 1 | a Mc Entee, K.u Univ Libre Bruxelles, Fac Med, Brussels, Belgium.4 aut |
700 | 1 | a Merveille, A. -C4 aut |
700 | 1 | a Wiberg, M.u Univ Helsinki, Fac Vet Med, Helsinki, Finland.4 aut |
700 | 1 | a Gouni, V.u Univ Paris Est Creteil, Ecole Natl Vet Alfort, Paris, France.;Hop Henri Mondor, INSERM, U955, Equipe 3, F-94010 Creteil, France.4 aut |
700 | 1 | a Willesen, J. Lundgrenu Univ Copenhagen, Fac Hlth & Med Sci, Copenhagen, Denmark.4 aut |
700 | 1 | a Hanås, Sofiau Swedish University of Agricultural Sciences,Sveriges lantbruksuniversitet,Institutionen för kliniska vetenskaper (KV),Department of Clinical Sciences,Evidensia Animal Clinic Västerås4 aut0 (Swepub:slu)109904 |
700 | 1 | a Wess, G.u Univ Munich, Munich, Germany.4 aut |
700 | 1 | a Sorensen, L. Mejeru Univ Copenhagen, Fac Hlth & Med Sci, Copenhagen, Denmark.4 aut |
700 | 1 | a Tiret, L.u Univ Paris Est Creteil, Ecole Natl Vet Alfort, Paris, France.;Hop Henri Mondor, INSERM, IMRB U955, Equipe BNMS 10, F-94010 Creteil, France.4 aut |
700 | 1 | a Kierczak, Marcinu Uppsala universitet,Institutionen för medicinsk biokemi och mikrobiologi,Uppsala University4 aut0 (Swepub:slu)49557 |
700 | 1 | a Forsberg, Simonu Swedish University of Agricultural Sciences,Sveriges lantbruksuniversitet,Institutionen för kliniska vetenskaper (KV),Department of Clinical Sciences4 aut0 (Swepub:slu)47020 |
700 | 1 | a Seppälä, E.u Univ Helsinki, Helsinki, Finland.;Folkhalsan Res Ctr, Helsinki, Finland.4 aut |
700 | 1 | a Lindblad-Toh, Kerstinu Uppsala universitet,Institutionen för medicinsk biokemi och mikrobiologi,Broad Inst MIT & Harvard, Cambridge, MA USA.4 aut0 (Swepub:uu)kerli865 |
700 | 1 | a Lohi, H.u Univ Helsinki, Helsinki, Finland.;Folkhalsan Res Ctr, Helsinki, Finland.4 aut |
700 | 1 | a Chetboul, V.u Univ Paris Est Creteil, Ecole Natl Vet Alfort, Paris, France.;Hop Henri Mondor, INSERM, U955, Equipe 3, F-94010 Creteil, France.4 aut |
700 | 1 | a Fredholm, M.u Univ Copenhagen, Fac Hlth & Med Sci, Copenhagen, Denmark.4 aut |
700 | 1 | a Häggström, Jensu Swedish University of Agricultural Sciences,Sveriges lantbruksuniversitet,Institutionen för kliniska vetenskaper (KV),Department of Clinical Sciences4 aut0 (Swepub:slu)48327 |
710 | 2 | a Sveriges lantbruksuniversitetb Institutionen för anatomi, fysiologi och biokemi4 org |
710 | 2 | a Sveriges lantbruksuniversitet |
773 | 0 | t Journal of Veterinary Internal Medicined : Wileyg 30:2, s. 566-573q 30:2<566-573x 0891-6640x 1939-1676 |
856 | 4 | u https://doi.org/10.1111/jvim.13829y Fulltext |
856 | 4 | u https://uu.diva-portal.org/smash/get/diva2:929605/FULLTEXT01.pdfx primaryx Raw objecty fulltext:print |
856 | 4 | u https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/jvim.13829 |
856 | 4 | u https://pub.epsilon.slu.se/id/eprint/14139/contentsx primaryx Raw objectx freey FULLTEXT |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-294337 |
856 | 4 8 | u https://doi.org/10.1111/jvim.13829 |
856 | 4 8 | u https://res.slu.se/id/publ/79901 |
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