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  • Cruz, Javier,1990-Uppsala universitet,Mikrosystemteknik (author)

High pressure inertial focusing for separating and concentrating bacteria at high throughput

  • Article/chapterEnglish2017

Publisher, publication year, extent ...

  • 2017-06-27
  • IOP PUBLISHING LTD,2017
  • electronicrdacarrier

Numbers

  • LIBRIS-ID:oai:DiVA.org:uu-329919
  • https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-329919URI
  • https://doi.org/10.1088/1361-6439/aa6b14DOI

Supplementary language notes

  • Language:English
  • Summary in:English

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  • Subject category:ref swepub-contenttype
  • Subject category:art swepub-publicationtype

Notes

  • Inertial focusing is a promising microfluidic technology for concentration and separation of particles by size. However, there is a strong correlation of increased pressure with decreased particle size. Theory and experimental results for larger particles were used to scale down the phenomenon and find the conditions that focus 1 mu m particles. High pressure experiments in robust glass chips were used to demonstrate the alignment. We show how the technique works for 1 mu m spherical polystyrene particles and for Escherichia coli, not being harmful for the bacteria at 50 mu l min(-1). The potential to focus bacteria, simplicity of use and high throughput make this technology interesting for healthcare applications, where concentration and purification of a sample may be required as an initial step.

Subject headings and genre

Added entries (persons, corporate bodies, meetings, titles ...)

  • Zadeh, S. HooshmandUppsala universitet,Institutionen för teknikvetenskaper (author)
  • Graells, TiscarUppsala universitet,Institutionen för medicinsk biokemi och mikrobiologi,Institutionen för teknikvetenskaper,Univ Autonoma Barcelona, Dept Genet & Microbiol, Barcelona, Spain.(Swepub:uu)tisgr283 (author)
  • Andersson, MartinUppsala universitet,Mikrosystemteknik(Swepub:uu)maran392 (author)
  • Malmström, JonasUppsala universitet,Institutionen för teknikvetenskaper(Swepub:uu)jomal226 (author)
  • Wu, Zhigang G.,1977-Uppsala universitet,Mikrosystemteknik,Huazhong Univ Sci & Technol, State Key Lab Digital Mfg Equipment & Technol, Wuhan, Peoples R China.(Swepub:uu)zhiwu265 (author)
  • Hjort, Klas,1964-Uppsala universitet,Mikrosystemteknik(Swepub:uu)klashjor (author)
  • Uppsala universitetMikrosystemteknik (creator_code:org_t)

Related titles

  • In:Journal of Micromechanics and Microengineering: IOP PUBLISHING LTD27:80960-13171361-6439

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