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FältnamnIndikatorerMetadata
00009235naa a2200877 4500
001oai:DiVA.org:uu-439082
003SwePub
008210406s2021 | |||||||||||000 ||eng|
009oai:prod.swepub.kib.ki.se:144940293
024a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-4390822 URI
024a https://doi.org/10.1002/cncr.332322 DOI
024a http://kipublications.ki.se/Default.aspx?queryparsed=id:1449402932 URI
040 a (SwePub)uud (SwePub)ki
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
100a Hong, Sangheeu Cleveland Clin, Taussig Canc Ctr, Blood & Marrow Transplant Program, 9500 Euclid Ave,CA60, Cleveland, OH 44195 USA.4 aut
2451 0a Community health status and outcomes after allogeneic hematopoietic cell transplantation in the United States
264 c 2020-10-21
264 1b John Wiley & Sons,c 2021
338 a print2 rdacarrier
520 a Background: The association of community factors and outcomes after hematopoietic cell transplantation (HCT) has not been comprehensively described. Using the County Health Rankings and Roadmaps (CHRR) and the Center for International Blood and Marrow Transplant Research (CIBMTR), this study evaluated the impact of community health status on allogeneic HCT outcomes.Methods: This study included 18,544 adult allogeneic HCT recipients reported to the CIBMTR by 170 US centers in 2014-2016. Sociodemographic, environmental, and community indicators were derived from the CHRR, an aggregate community risk score was created, and scores were assigned to each patient (patient community risk score [PCS]) and transplant center (center community risk score [CCS]). Higher scores indicated less healthy communities. The impact of PCS and CCS on patient outcomes after allogeneic HCT was studied.Results: The median age was 55 years (range, 18-83 years). The median PCS was -0.21 (range, -1.37 to 2.10; standard deviation [SD], 0.42), and the median CCS was -0.13 (range, -1.04 to 0.96; SD, 0.40). In multivariable analyses, a higher PCS was associated with inferior survival (hazard ratio [HR] per 1 SD increase, 1.04; 99% CI, 1.00-1.08;P= .0089). Among hematologic malignancies, a tendency toward inferior survival was observed with a higher PCS (HR, 1.04; 99% CI, 1.00-1.08;P= .0102); a higher PCS was associated with higher nonrelapse mortality (NRM; HR, 1.08; 99% CI, 1.02-1.15;P= .0004). CCS was not significantly associated with survival, relapse, or NRM.Conclusions: Patients residing in counties with a worse community health status have inferior survival as a result of an increased risk of NRM after allogeneic HCT. There was no association between the community health status of the transplant center location and allogeneic HCT outcomes.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Cancer och onkologi0 (SwePub)302032 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cancer and Oncology0 (SwePub)302032 hsv//eng
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Hematologi0 (SwePub)302022 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Hematology0 (SwePub)302022 hsv//eng
653 a allogeneic transplant
653 a community health
653 a hematopoietic cell transplantation
653 a survival
700a Brazauskas, Rutau Med Coll Wisconsin, Dept Med, Ctr Int Blood & Marrow Transplant Res, Milwaukee, WI 53226 USA.;Med Coll Wisconsin, Inst Hlth & Equ, Div Biostat, Milwaukee, WI 53226 USA.4 aut
700a Hebert, Kyle M.u Med Coll Wisconsin, Dept Med, Ctr Int Blood & Marrow Transplant Res, Milwaukee, WI 53226 USA.4 aut
700a Ganguly, Siddharthau Univ Kansas Hlth Syst, Div Hematol Malignancy & Cellular Therapeut, Kansas City, KS USA.4 aut
700a Abdel-Azim, Hishamu Univ Southern Calif, Childrens Hosp Los Angeles, Keck Sch Med, Div Hematol Oncol & Blood & Marrow Transplantat, Los Angeles, CA 90007 USA.4 aut
700a Diaz, Miguel Angelu Univ Nino Jesus, Dept Hematol Oncol, Hosp Infantil, Madrid, Spain.4 aut
700a Beattie, Sarau Tom Baker Canc Clin, Dept Psychosocial Oncol & Rehabil, Calgary, AB, Canada.;Univ Calgary, Dept Oncol, Calgary, AB, Canada.4 aut
700a Ciurea, Stefan O.u Univ Texas MD Anderson Canc Ctr, Houston, TX 77030 USA.4 aut
700a Szwajcer, Davidu Univ Manitoba, Winnipeg, MB, Canada.,King Faisal Specialist Hosp & Res Ctr, Dept Oncol, Riyadh, Saudi Arabia.4 aut
700a Badawy, Sherif M.u Ann & Robert H Lurie Childrens Hosp Chicago, Div Hematol Oncol & Stem Cell Transplant, Chicago, IL 60611 USA.;Northwestern Univ, Dept Pediat, Feinberg Sch Med, Chicago, IL 60611 USA.4 aut
700a Gratwohl, Alois A.u Univ Hosp Basel, Basel, Switzerland.4 aut
700a LeMaistre, Charlesu Sarah Cannon, Hematol & Bone Marrow Transplant, Nashville, TN USA.4 aut
700a Aljurf, Mahmoud D. S. M.u King Faisal Specialist Hosp & Res Ctr, Dept Oncol, Riyadh, Saudi Arabia.,Dokkyo Med Univ, Dept Hematol & Oncol, Mibu, Tochigi, Japan.4 aut
700a Olsson, Richardu Uppsala universitet,Centrum för klinisk forskning i Sörmland (CKFD),Karolinska Inst, Dept Lab Med, Stockholm, Sweden.4 aut0 (Swepub:uu)riols677
700a Bhatt, Neel S.u Fred Hutchinson Canc Res Ctr, 1124 Columbia St, Seattle, WA 98104 USA.4 aut
700a Farhadfar, Noshau Univ Florida, Coll Med, Div Hematol Oncol, Gainesville, FL USA.4 aut
700a Yared, Jean A.u Univ Maryland, Dept Med, Blood & Marrow Transplantat Program, Div Hematol Oncol,Greenebaum Comprehens Canc Ctr, Baltimore, MD 21201 USA.4 aut
700a Yoshimi, Ayamiu Univ Freiburg, Div Pediat Hematol & Oncol, Dept Pediat & Adolescent Med, Med Ctr, Freiburg, Germany.4 aut
700a Seo, Sachikou Dokkyo Med Univ, Dept Hematol & Oncol, Mibu, Tochigi, Japan.,Cleveland Clin, Taussig Canc Ctr, Blood & Marrow Transplant Program, 9500 Euclid Ave,CA60, Cleveland, OH 44195 USA.4 aut
700a Gergis, Usamau Thomas Jefferson Univ, Philadelphia, PA 19107 USA.4 aut
700a Beitinjaneh, Amer M.u Univ Miami, Miami, FL USA.4 aut
700a Sharma, Akshayu St Jude Childrens Res Hosp, Dept Bone Marrow Transplantat & Cellular Therapy, 332 N Lauderdale St, Memphis, TN 38105 USA.4 aut
700a Lazarus, Hillardu Case Western Reserve Univ, Univ Hosp Cleveland, Med Ctr, Cleveland, OH 44106 USA.4 aut
700a Law, Jasonu Tufts Med Ctr, Div Pediat Hematol Oncol, Floating Hosp Children, Boston, MA 02111 USA.4 aut
700a Ulrickson, Matthewu Banner MD Anderson Canc Ctr, Gilbert, AZ USA.4 aut
700a Hashem, Hasanu King Hussein Canc Ctr, Div Pediat Hematol Oncol & Bone Marrow Transplant, Amman, Jordan.4 aut
700a Schoemans, Heleneu Univ Hosp Leuven, Dept Hematol, Leuven, Belgium.;Katholieke Univ Leuven, Leuven, Belgium.4 aut
700a Cerny, Janu Univ Massachusetts, Med Ctr, Dept Med, Div Hematol Oncol, Worcester, MA USA.4 aut
700a Rizzieri, Davidu Duke Univ, Div Hematol Malignancies & Cellular Therapy, Durham, NC USA.4 aut
700a Savani, Bipin N.u Vanderbilt Univ, Med Ctr, Dept Med, Div Hematol Oncol, Nashville, TN USA.4 aut
700a Kamble, Rammurti T.u Baylor Coll Med, Div Hematol & Oncol, Ctr Cell & Gene Therapy, Houston, TX 77030 USA.4 aut
700a Shaw, Bronwen E.u Med Coll Wisconsin, Dept Med, Ctr Int Blood & Marrow Transplant Res, Milwaukee, WI 53226 USA.4 aut
700a Khera, Nanditau Mayo Clin, Dept Hematol Oncol, Phoenix, AZ USA.4 aut
700a Wood, William A.u Univ N Carolina, Dept Med, Div Hematol Oncol, Chapel Hill, NC 27515 USA.4 aut
700a Hashmi, Shahrukhu Mayo Clin, Dept Internal Med, Rochester, MN USA.4 aut
700a Hahn, Theresau Roswell Park Comprehens Canc Ctr, Dept Med, Buffalo, NY USA.4 aut
700a Lee, Stephanie J.u Med Coll Wisconsin, Dept Med, Ctr Int Blood & Marrow Transplant Res, Milwaukee, WI 53226 USA.;Fred Hutchinson Canc Res Ctr, 1124 Columbia St, Seattle, WA 98104 USA.4 aut
700a Rizzo, J. Douglasu Med Coll Wisconsin, Dept Med, Ctr Int Blood & Marrow Transplant Res, Milwaukee, WI 53226 USA.4 aut
700a Majhail, Navneet S.u Cleveland Clin, Taussig Canc Ctr, Blood & Marrow Transplant Program, 9500 Euclid Ave,CA60, Cleveland, OH 44195 USA.4 aut
700a Saber, Waelu Med Coll Wisconsin, Dept Med, Ctr Int Blood & Marrow Transplant Res, Milwaukee, WI 53226 USA.4 aut
710a Cleveland Clin, Taussig Canc Ctr, Blood & Marrow Transplant Program, 9500 Euclid Ave,CA60, Cleveland, OH 44195 USA.b Med Coll Wisconsin, Dept Med, Ctr Int Blood & Marrow Transplant Res, Milwaukee, WI 53226 USA.;Med Coll Wisconsin, Inst Hlth & Equ, Div Biostat, Milwaukee, WI 53226 USA.4 org
773t Cancerd : John Wiley & Sonsg 127:4, s. 609-618q 127:4<609-618x 0008-543Xx 1097-0142
856u https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/cncr.33232
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-439082
8564 8u https://doi.org/10.1002/cncr.33232
8564 8u http://kipublications.ki.se/Default.aspx?queryparsed=id:144940293

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