Changes to lung surfactant monolayers upon exposure to gas phase ozone observed using X-ray and neutron reflectivity

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Fältnamn	Indikatorer	Metadata
000		03431naa a2200385 4500
001		oai:DiVA.org:uu-485023
003		SwePub
008		220921s2022 \| \|\|\|\|\|\|\|\|\|\|\|000 \|\|eng\|
024	7	a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-4850232 URI
024	7	a https://doi.org/10.1039/d2ea00032f2 DOI
040		a (SwePub)uu
041		a engb eng
042		9 SwePub
072	7	a ref2 swepub-contenttype
072	7	a art2 swepub-publicationtype
100	1	a Hemming, Joanna M.u Univ London, Dept Biol Sci, Inst Struct & Mol Biol, Malet St, London WC1E 7HX, England.4 aut
245	1 0	a Changes to lung surfactant monolayers upon exposure to gas phase ozone observed using X-ray and neutron reflectivity
264		c 2022
264	1	b Royal Society of Chemistry,c 2022
338		a electronic2 rdacarrier
520		a Exposure to the secondary pollutant ozone in ambient air is associated with adverse health effects when inhaled. In this work we use surface pressure measurements, combined with X-ray and neutron reflection, to observe changes in a layer of lung surfactant at the air water interface when exposed to gas phase ozone. The results demonstrate that the layer reacts with ozone changing its physical characteristics. A slight loss of material, a significant thinning of the layer and increased hydration of the surfactant material is observed. The results support the hypothesis that unsaturated lipids present in lung surfactant are still susceptible to rapid reaction with ozone and the reaction changes the properties of the interfacial layer.
650	7	a NATURVETENSKAPx Kemix Materialkemi0 (SwePub)104032 hsv//swe
650	7	a NATURAL SCIENCESx Chemical Sciencesx Materials Chemistry0 (SwePub)104032 hsv//eng
700	1	a Szyroka, Justynau Univ London, Dept Biol Sci, Inst Struct & Mol Biol, Malet St, London WC1E 7HX, England.4 aut
700	1	a Shokano, Graciau Univ London, Dept Biol Sci, Inst Struct & Mol Biol, Malet St, London WC1E 7HX, England.4 aut
700	1	a Arnold, Thomasu European Spallat Source, ESS Campus, Lund, Sweden.;CISIS Neutron & Muon Source, Sci & Technol Fac Council, Rutherford Appleton Lab, Harwell OX11 0QX, Berks, England.;Univ Bath, Dept Chem, Claverton Down, Bath BA2 7AY, Avon, England.4 aut
700	1	a Skoda, Maximilian W. A.u CISIS Neutron & Muon Source, Sci & Technol Fac Council, Rutherford Appleton Lab, Harwell OX11 0QX, Berks, England.4 aut
700	1	a Rennie, Adrian R.,d 1957-u Uppsala universitet,Institutionen för fysik och astronomi4 aut0 (Swepub:uu)adren227
700	1	a Thompson, Katherine C.u Univ London, Dept Biol Sci, Inst Struct & Mol Biol, Malet St, London WC1E 7HX, England.4 aut
710	2	a Univ London, Dept Biol Sci, Inst Struct & Mol Biol, Malet St, London WC1E 7HX, England.b European Spallat Source, ESS Campus, Lund, Sweden.;CISIS Neutron & Muon Source, Sci & Technol Fac Council, Rutherford Appleton Lab, Harwell OX11 0QX, Berks, England.;Univ Bath, Dept Chem, Claverton Down, Bath BA2 7AY, Avon, England.4 org
773	0	t Environmental Scienced : Royal Society of Chemistryg 2:4, s. 753-760q 2:4<753-760x 2634-3606
856	4	u https://doi.org/10.1039/d2ea00032fy Fulltext
856	4	u https://uu.diva-portal.org/smash/get/diva2:1697775/FULLTEXT01.pdfx primaryx Raw objecty fulltext:print
856	4 8	u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-485023
856	4 8	u https://doi.org/10.1039/d2ea00032f

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Av författaren/redakt...: Hemming, Joanna ...; Szyroka, Justyna; Shokano, Gracia; Arnold, Thomas; Skoda, Maximilia ...; Rennie, Adrian R ...; visa fler...; Thompson, Kather ...; visa färre...

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