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Sökning: onr:"swepub:oai:DiVA.org:uu-513127" > Understanding the e...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00007927naa a2200913 4500
001oai:DiVA.org:uu-513127
003SwePub
008231003s2023 | |||||||||||000 ||eng|
009oai:lup.lub.lu.se:745e029d-e306-4d8b-b82b-9ee4ff8411de
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-5131272 URI
0247 a https://doi.org/10.1111/jeb.141812 DOI
0247 a https://lup.lub.lu.se/record/745e029d-e306-4d8b-b82b-9ee4ff8411de2 URI
040 a (SwePub)uud (SwePub)lu
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a for2 swepub-publicationtype
1001 a Vinkler, Michalu Charles Univ Prague, Fac Sci, Dept Zool, Prague, Czech Republic.,Charles University in Prague4 aut
2451 0a Understanding the evolution of immune genes in jawed vertebrates
264 1b John Wiley & Sons,c 2023
338 a electronic2 rdacarrier
520 a Driven by co-evolution with pathogens, host immunity continuously adapts to optimize defence against pathogens within a given environment. Recent advances in genetics, genomics and transcriptomics have enabled a more detailed investigation into how immunogenetic variation shapes the diversity of immune responses seen across domestic and wild animal species. However, a deeper understanding of the diverse molecular mechanisms that shape immunity within and among species is still needed to gain insight into-and generate evolutionary hypotheses on-the ultimate drivers of immunological differences. Here, we discuss current advances in our understanding of molecular evolution underpinning jawed vertebrate immunity. First, we introduce the immunome concept, a framework for characterizing genes involved in immune defence from a comparative perspective, then we outline how immune genes of interest can be identified. Second, we focus on how different selection modes are observed acting across groups of immune genes and propose hypotheses to explain these differences. We then provide an overview of the approaches used so far to study the evolutionary heterogeneity of immune genes on macro and microevolutionary scales. Finally, we discuss some of the current evidence as to how specific pathogens affect the evolution of different groups of immune genes. This review results from the collective discussion on the current key challenges in evolutionary immunology conducted at the ESEB 2021 Online Satellite Symposium: Molecular evolution of the vertebrate immune system, from the lab to natural populations.
650 7a NATURVETENSKAPx Biologix Evolutionsbiologi0 (SwePub)106152 hsv//swe
650 7a NATURAL SCIENCESx Biological Sciencesx Evolutionary Biology0 (SwePub)106152 hsv//eng
650 7a NATURVETENSKAPx Biologix Immunologi0 (SwePub)106052 hsv//swe
650 7a NATURAL SCIENCESx Biological Sciencesx Immunology0 (SwePub)106052 hsv//eng
650 7a MEDICIN OCH HÄLSOVETENSKAPx Medicinska och farmaceutiska grundvetenskaperx Immunologi inom det medicinska området0 (SwePub)301102 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Basic Medicinex Immunology in the medical area0 (SwePub)301102 hsv//eng
653 a adaptation
653 a adaptive immunity
653 a evolutionary immunology
653 a genomics
653 a host-parasite interactions
653 a immunogenetics
653 a innate immunity
653 a MHC
653 a molecular evolution
653 a vertebrates
653 a adaptation
653 a adaptive immunity
653 a evolutionary immunology
653 a genomics
653 a host-parasite interactions
653 a immunogenetics
653 a innate immunity
653 a MHC
653 a molecular evolution
653 a vertebrates
7001 a Fiddaman, Steven R.u Univ Oxford, Dept Biol, Oxford, England.,University of Oxford4 aut
7001 a Tesický, Martinu Charles Univ Prague, Fac Sci, Dept Zool, Prague, Czech Republic.,Charles University in Prague4 aut
7001 a O'Connor, Emily A.u Lund University,Lunds universitet,MEMEG,Biologiska institutionen,Naturvetenskapliga fakulteten,Molekylär ekologi och evolution,Forskargrupper vid Lunds universitet,CAnMove - Centrum för forskning om djurs spridning och flyttning,Department of Biology,Faculty of Science,Molecular Ecology and Evolution Lab,Lund University Research Groups,CAnMove - Centre for Animal Movement Research4 aut0 (Swepub:lu)biol-eio
7001 a Savage, Anna E.u Univ Cent Florida, Dept Biol, Orlando, FL USA.,University of Central Florida4 aut
7001 a Lenz, Tobias L.u Univ Hamburg, Dept Biol, Res Unit Evolutionary Immunogen, Hamburg, Germany.,University of Hamburg4 aut
7001 a Smith, Adrian L.u Univ Oxford, Dept Biol, Oxford, England.,University of Oxford4 aut
7001 a Kaufman, Jimu Univ Edinburgh, Inst Immunol & Infect Res, Edinburgh, Scotland.;Univ Cambridge, Dept Vet Med, Cambridge, England.,University of Edinburgh4 aut
7001 a Bolnick, Daniel I.u Univ Connecticut, Dept Ecol & Evolutionary Biol, Storrs, CT USA.,University of Connecticut4 aut
7001 a Davies, Charli S.u Univ East Anglia, Sch Biol Sci, Norwich, England.,University of East Anglia4 aut
7001 a Dedic, Neirau Masaryk Univ, Dept Bot & Zool, Brno, Czech Republic.,Masaryk University4 aut
7001 a Flies, Andrew S.u Univ Tasmania, Menzies Inst Med Res, Hobart, Tas, Australia.,Menzies Institute for Medical Research4 aut
7001 a Gomez Samblas, M. Mercedesu Univ Granada, Dept Parasitol, Granada, Spain.,University of Granada,Charles University in Prague4 aut
7001 a Henschen, Amberleigh E.u Univ Memphis, Dept Biol Sci, Memphis, TN USA.,University of Memphis4 aut
7001 a Novák, Karelu Inst Anim Sci, Dept Genet & Breeding, Uhrinrves, Czech Republic.4 aut
7001 a Palomar, Gemmau Jagiellonian Univ, Inst Environm Sci, Fac Biol, Krakow, Poland.,Jagiellonian University4 aut
7001 a Raven, Nynkeu Deakin Univ, Dept Sci Engn & Build Environm, Waurn Ponds, Vic, Australia.,Deakin University4 aut
7001 a Samaké, Kalifau Charles Univ Prague, Fac Sci, Dept Genet & Microbiol, Prague, Czech Republic.,Charles University in Prague4 aut
7001 a Slade, Joelu Calif State Univ, Dept Biol, Fresno, CA USA.4 aut
7001 a Kuttiyarthu Veetil, Nithyau Charles Univ Prague, Fac Sci, Dept Zool, Prague, Czech Republic.,Charles University in Prague4 aut
7001 a Voukali, Eleniu Charles Univ Prague, Fac Sci, Dept Zool, Prague, Czech Republic.,Charles University in Prague4 aut
7001 a Höglund, Jacobu Uppsala University,Uppsala universitet,Zooekologi4 aut0 (Swepub:uu)jacohogl
7001 a Richardson, David S.u University of East Anglia4 aut0 (Swepub:lu)zooe-dri
7001 a Westerdahl, Helenau Lund University,Lunds universitet,MEMEG,Biologiska institutionen,Naturvetenskapliga fakulteten,Molekylär ekologi och evolution,Forskargrupper vid Lunds universitet,CAnMove - Centrum för forskning om djurs spridning och flyttning,Department of Biology,Faculty of Science,Molecular Ecology and Evolution Lab,Lund University Research Groups,CAnMove - Centre for Animal Movement Research4 aut0 (Swepub:lu)ekol-hwe
7102 a Charles Univ Prague, Fac Sci, Dept Zool, Prague, Czech Republic.b Charles University in Prague4 org
7730 t Journal of Evolutionary Biologyd : John Wiley & Sonsg 36:6, s. 847-873q 36:6<847-873x 1010-061Xx 1420-9101
8564 u https://doi.org/10.1111/jeb.14181y Fulltext
8564 u https://uu.diva-portal.org/smash/get/diva2:1802127/FULLTEXT01.pdfx primaryx Raw objecty fulltext:print
8564 u http://dx.doi.org/10.1111/jeb.14181x freey FULLTEXT
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-513127
8564 8u https://doi.org/10.1111/jeb.14181
8564 8u https://lup.lub.lu.se/record/745e029d-e306-4d8b-b82b-9ee4ff8411de

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