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Sökning: onr:"swepub:oai:DiVA.org:uu-57044" > Childbearing and th...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00002877naa a2200349 4500
001oai:DiVA.org:uu-57044
003SwePub
008081017s1998 | |||||||||||000 ||eng|
009oai:prod.swepub.kib.ki.se:1935092
024a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-570442 URI
024a http://kipublications.ki.se/Default.aspx?queryparsed=id:19350922 URI
040 a (SwePub)uud (SwePub)ki
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
100a Lambe, Matsu Karolinska Institutet4 aut
2451 0a Childbearing and the risk of Hodgkin's disease
264 1c 1998
338 a print2 rdacarrier
520 a The causes of Hodgkin's disease remain incompletely known, but a higher incidence in men than in women has prompted an interest in the role of female sex hormones and reproductive history. Available epidemiological data are, however, contradictory. We analyzed possible associations between parity, age at first birth, and the risk of developing Hodgkin's disease by a linkage between the Swedish Cancer Register and a nationwide Fertility Register. Among women born between 1925 and 1972, 917 cases with Hodgkin's disease and concomitant fertility information were identified. For each case patient, five age-matched controls were randomly selected among women in the Fertility Register. Conditional logistic regression was used to estimate odds ratios of Hodgkin's disease associated with a birth. We found a slightly and nonsignificantly reduced risk of Hodgkin's disease in ever-parous compared with nulliparous women. Among parous women, the number of children was unrelated to risk, whereas there was some evidence of an increased risk with late age at first birth in women under age 45 at diagnosis. No clear temporal relations between childbearing and subsequent risk were discernible in any parity or age group. Although uncontrolled confounding might have affected our results, they do not indicate that hormonal or immunological changes associated with childbearing play a role in the development of Hodgkin's disease.
653 a MEDICINE
653 a MEDICIN
700a Hsieh, Chung-Cheng4 aut
700a Tsaih, Shirng-wern4 aut
700a Adami, Johanna4 aut
700a Glimelius, Bengtu Karolinska Institutet,Uppsala universitet,Institutionen för onkologi, radiologi och klinisk immunologi,Onkol4 aut
700a Adami, Hans-Olovu Karolinska Institutet4 aut
710a Karolinska Institutetb Institutionen för onkologi, radiologi och klinisk immunologi4 org
773t Cancer Epidemiology, Biomarkers and Preventiong 7:9, s. 831-834q 7:9<831-834x 1055-9965x 1538-7755
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-57044
8564 8u http://kipublications.ki.se/Default.aspx?queryparsed=id:1935092

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