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Reaction mechanism of glyoxalase I explored by an X-ray crystallographic analysis of the human enzyme in complex with a transition state analogue
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- Cameron, AD (author)
- Uppsala universitet
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- Ridderstrom, M (author)
- Uppsala universitet
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- Olin, B (author)
- Uppsala universitet
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- AMER CHEMICAL SOC, 1999
- 1999
- English.
- In: BIOCHEMISTRY. - : AMER CHEMICAL SOC. - 0006-2960. ; 38:41, s. 13480-13490
- Journal article (other academic/artistic)
Abstract
Subject headings
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- The structures of human glyoxalase I in complexes with S-(N-hydroxy-N-p-iodophenylcarbamoyl)glutathione (HIPC-GSH) and S-p-nitrobenzyloxycarbonylglutathione (NBC-GSH) have been determined at 2.0 and 1.72 Angstrom resolution, respectively. HIPC-GSH is a tr
Keyword
- ACTIVE-SITE; TRIOSEPHOSPHATE ISOMERASE; SUBSTRATE USAGE; REFINEMENT; SYSTEM; METAL; NMR; DERIVATIVES; INHIBITORS; RESONANCE
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- art (subject category)
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- Cameron, AD
- Ridderstrom, M
- Olin, B
- Kavarana, MJ
- Creighton, DJ
- Mannervik, B
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- BIOCHEMISTRY
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- Uppsala University
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