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LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00004906naa a2200829 4500
001oai:gup.ub.gu.se/102904
003SwePub
008240528s2009 | |||||||||||000 ||eng|
009oai:research.chalmers.se:a3429afc-723e-4270-bced-9de125c970d2
009oai:DiVA.org:uu-107695
009oai:prod.swepub.kib.ki.se:118097717
024a https://gup.ub.gu.se/publication/1029042 URI
024a https://doi.org/10.1016/j.ajog.2008.08.0662 DOI
024a https://research.chalmers.se/publication/1029042 URI
024a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-1076952 URI
024a http://kipublications.ki.se/Default.aspx?queryparsed=id:1180977172 URI
040 a (SwePub)gud (SwePub)cthd (SwePub)uud (SwePub)ki
041 a eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
100a Orgeas, Cu Dept of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden4 aut
2451 0a Breast cancer incidence after hormonal infertility treatment in Sweden: a cohort study
264 1b Elsevier BV,c 2009
520 a OBJECTIVE: To assess the impact of infertility treatment with causes of infertility on incidence of breast cancer. STUDY DESIGN: Historical prospective cohort study of 1135 women attending major university clinics for treatment of infertility in Sweden, 1961-1976. Women were classified as users of clomiphene citrate or gonadotropins, or a combination of both therapies. Standardized incidence ratios were calculated to estimate relative risk of breast cancer. RESULTS: We observed 54 cases of breast cancer during 1961-2004, which did not significantly exceed those expected. Users of high-dose clomiphene citrate had an almost 2-fold increased risk (standardized incidence ratio, 1.90; 95% confidence interval, 1.08-3.35). This association was more pronounced among women referred for nonovulatory factors, with 3-fold increased risk (standardized incidence ratio, 3.00; 95% confidence interval, 1.35-6.67). CONCLUSION: No overall increased risk for breast cancer was shown with infertility treatment. Women with nonovulatory causes treated with high-dose clomiphene citrate therapy may have an elevated risk for breast cancer.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Reproduktionsmedicin och gynekologi0 (SwePub)302202 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Obstetrics, Gynaecology and Reproductive Medicine0 (SwePub)302202 hsv//eng
653 a Adult
653 a Breast Neoplasms/*chemically induced/epidemiology
653 a Chorionic Gonadotropin/*adverse effects/therapeutic use
653 a Clomiphene/*adverse effects/therapeutic use
653 a Cohort Studies
653 a Female
653 a Fertility Agents
653 a Female/*adverse effects/therapeutic use
653 a Humans
653 a Incidence
653 a Infertility
653 a Female/*drug therapy
653 a Prospective Studies
653 a Sweden/epidemiology
653 a ovulation induction
653 a postmenopausal women
653 a fertility drugs
653 a risk
653 a therapy
653 a health
653 a carcinogenesis
653 a prevention
653 a pregnancy
653 a estrogens
653 a Incidence
653 a MEDICINE
700a Sanner, Karinu Uppsala universitet,Institutionen för kvinnors och barns hälsa,Klinisk och experimentell reproduktionsbiologi/Olovsson4 aut0 (Swepub:uu)karisann
700a Hall, Peru Karolinska Institutet4 aut
700a Conner, Peter4 aut
700a Holte, Janu Carl von Linne Kliniken, Uppsala University Hospital, Uppsala, Sweden4 aut
700a Nilsson, Staffan,d 19564 aut
700a Sundfeldt, Karin,d 1962u Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper,Institute of Clinical Sciences,University of Gothenburg4 aut0 (Swepub:gu)xsukar
700a Persson, Ingemar4 aut
700a Chia, Kee Seng4 aut
700a Wedren, Sarau Karolinska Institutet4 aut
700a Dickman, Paulu Karolinska Institutet4 aut
700a Czene, Kamillau Karolinska Institutet4 aut
710a Dept of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Swedenb Institutionen för kvinnors och barns hälsa4 org
773t Am J Obstet Gynecold : Elsevier BVg 200:1q 200:1x 0002-9378x 1097-6868
856u http://dx.doi.org/10.1016/j.ajog.2008.08.066y FULLTEXT
8564 8u https://gup.ub.gu.se/publication/102904
8564 8u https://doi.org/10.1016/j.ajog.2008.08.066
8564 8u https://research.chalmers.se/publication/102904
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-107695
8564 8u http://kipublications.ki.se/Default.aspx?queryparsed=id:118097717

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