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Increased MMP-9 and TIMP-1 in mouse neonatal brain and plasma and in human neonatal plasma after hypoxia-ischemia: a potential marker of neonatal encephalopathy.
- Bednarek, Nathalie (author)
-
- Svedin, Pernilla, 1979 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi,Institute of Neuroscience and Physiology
- Garnotel, Roselyne (author)
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- Favrais, Géraldine (author)
- Loron, Gauthier (author)
- Schwendiman, Leslie (author)
- Morville, Patrice (author)
- Gressens, Pierre (author)
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- (creator_code:org_t)
- 2011-12-15
- 2012
- English.
- In: Pediatric research. - : Springer Science and Business Media LLC. - 1530-0447 .- 0031-3998. ; 71:1, s. 63-70
- Journal article (peer-reviewed)
Abstract
Subject headings
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- To implement neuroprotective strategies in newborns, sensitive and specific biomarkers are needed for identifying those who are at risk for brain damage. We evaluated the effectiveness of matrix metalloproteinases (MMPs) and their naturally occurring tissue inhibitors of metalloproteinases (TIMPs) in predicting neonatal encephalopathy (NE) damage in newborns.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Pediatrik (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Pediatrics (hsv//eng)
Keyword
- Animals
- Animals
- Newborn
- Biological Markers
- metabolism
- Brain
- metabolism
- pathology
- Female
- Gestational Age
- Humans
- Hypoxia-Ischemia
- Brain
- pathology
- physiopathology
- Infant
- Newborn
- Infant
- Newborn
- Diseases
- pathology
- physiopathology
- Male
- Matrix Metalloproteinase 9
- blood
- Mice
- Mice
- Inbred C57BL
- Tissue Inhibitor of Metalloproteinase-1
- blood
Publication and Content Type
- ref (subject category)
- art (subject category)
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- University of Gothenburg
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