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| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 06231naa a2201201 4500 | |
| 001 | oai:gup.ub.gu.se/162719 | |
| 003 | SwePub | |
| 008 | 240528s2012 | |||||||||||000 ||eng| | |
| 009 | oai:lup.lub.lu.se:2051cdbb-4af9-4037-a938-a0429ce782a1 | |
| 009 | oai:DiVA.org:umu-57228 | |
| 009 | oai:prod.swepub.kib.ki.se:125005121 | |
| 024 | 7 | a https://gup.ub.gu.se/publication/1627192 URI |
| 024 | 7 | a https://doi.org/10.1002/ijc.275472 DOI |
| 024 | 7 | a https://lup.lub.lu.se/record/30734602 URI |
| 024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-572282 URI |
| 024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:1250051212 URI |
| 040 | a (SwePub)gud (SwePub)lud (SwePub)umud (SwePub)ki | |
| 041 | a eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a ref2 swepub-contenttype |
| 072 | 7 | a art2 swepub-publicationtype |
| 100 | 1 | a Molina-Montes, E.4 aut |
| 245 | 1 0 | a Dietary intake of iron, heme-iron and magnesium and pancreatic cancer risk in the European prospective investigation into cancer and nutrition cohort |
| 264 | c 2012-04-16 | |
| 264 | 1 | b Wiley,c 2012 |
| 520 | a Several studies support a protective effect of dietary magnesium against type 2 diabetes, but a harmful effect for iron. As diabetes has been linked to pancreatic cancer, intake of these nutrients may be also associated with this cancer. We examined the association between dietary intake of magnesium, total iron and heme-iron and pancreatic cancer risk in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort. In total, 142,203 men and 334,999 women, recruited between 1992 and 2000, were included. After an average follow-up of 11.3 years, 396 men and 469 women developed exocrine pancreatic cancer. Hazard ratios and 95% confidence intervals (CIs) were obtained using Cox regression stratified by age and center, and adjusted for energy intake, smoking status, height, weight, and self-reported diabetes status. Neither intake of magnesium, total iron nor heme-iron was associated with pancreatic cancer risk. In stratified analyses, a borderline inverse association was observed among overweight men (body mass index, =25 kg/m2) with magnesium (HRper 100 mg/day increase = 0.79, 95% CI = 0.631.01) although this was less apparent using calibrated intake. In female smokers, a higher intake of heme-iron was associated with a higher pancreatic cancer risk (HR per 1 mg/day increase = 1.38, 95% CI = 1.101.74). After calibration, this risk increased significantly to 2.5-fold (95% CI = 1.225.28). Overall, dietary magnesium, total iron and heme-iron were not associated with pancreatic cancer risk during the follow-up period. Our observation that heme-iron was associated with increased pancreatic cancer risk in female smokers warrants replication in additional study populations. | |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Cancer och onkologi0 (SwePub)302032 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cancer and Oncology0 (SwePub)302032 hsv//eng |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Kirurgi0 (SwePub)302122 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Surgery0 (SwePub)302122 hsv//eng |
| 653 | a diet | |
| 653 | a magnesium | |
| 653 | a iron | |
| 653 | a nutrients | |
| 653 | a pancreatic cancer | |
| 653 | a cohort | |
| 653 | a epidemiology | |
| 653 | a diabetes-mellitus | |
| 653 | a insulin-resistance | |
| 653 | a energy-intake | |
| 653 | a epic project | |
| 653 | a meat | |
| 653 | a metaanalysis | |
| 653 | a calibration | |
| 653 | a disease | |
| 653 | a women | |
| 653 | a men | |
| 653 | a diet | |
| 700 | 1 | a Wark, P. A.4 aut |
| 700 | 1 | a Sanchez, M. J.4 aut |
| 700 | 1 | a Norat, T.4 aut |
| 700 | 1 | a Jakszyn, P.4 aut |
| 700 | 1 | a Lujan-Barroso, L.4 aut |
| 700 | 1 | a Michaud, D. S.4 aut |
| 700 | 1 | a Crowe, F.4 aut |
| 700 | 1 | a Allen, N.4 aut |
| 700 | 1 | a Khaw, K. T.4 aut |
| 700 | 1 | a Wareham, N.4 aut |
| 700 | 1 | a Trichopoulou, A.4 aut |
| 700 | 1 | a Adarakis, G.4 aut |
| 700 | 1 | a Katarachia, H.4 aut |
| 700 | 1 | a Skeie, G.4 aut |
| 700 | 1 | a Henningsen, M.4 aut |
| 700 | 1 | a Broderstad, A. R.4 aut |
| 700 | 1 | a Berrino, F.4 aut |
| 700 | 1 | a Tumino, R.4 aut |
| 700 | 1 | a Palli, D.4 aut |
| 700 | 1 | a Mattiello, A.4 aut |
| 700 | 1 | a Vineis, P.4 aut |
| 700 | 1 | a Amiano, P.4 aut |
| 700 | 1 | a Barricarte, A.4 aut |
| 700 | 1 | a Huerta, J. M.4 aut |
| 700 | 1 | a Duell, E. J.4 aut |
| 700 | 1 | a Quiros, J. R.4 aut |
| 700 | 1 | a Ye, W. M.u Karolinska Institutet4 aut |
| 700 | 1 | a Sund, Malin,d 1972-u Umeå universitet,Kirurgi,Näringsforskning,Malin Sund4 aut0 (Swepub:umu)masu0021 |
| 700 | 1 | a Lindkvist, Björnu Gothenburg University,Göteborgs universitet,Institutionen för medicin,Institute of Medicine4 aut0 (Swepub:gu)xlibjo |
| 700 | 1 | a Johansen, Dortheu Lund University,Lunds universitet,Kirurgi,Forskargrupper vid Lunds universitet,Surgery,Lund University Research Groups4 aut0 (Swepub:lu)kirm-djo |
| 700 | 1 | a Overvad, K.4 aut |
| 700 | 1 | a Tjonneland, A.4 aut |
| 700 | 1 | a Roswall, N.4 aut |
| 700 | 1 | a Li, K. R.4 aut |
| 700 | 1 | a Grote, V. A.4 aut |
| 700 | 1 | a Steffen, A.4 aut |
| 700 | 1 | a Boeing, H.4 aut |
| 700 | 1 | a Racine, A.4 aut |
| 700 | 1 | a Boutron-Ruault, M. C.4 aut |
| 700 | 1 | a Carbonnel, F.4 aut |
| 700 | 1 | a Peeters, P. H. M.4 aut |
| 700 | 1 | a Siersema, P. D.4 aut |
| 700 | 1 | a Fedirko, V.4 aut |
| 700 | 1 | a Jenab, M.4 aut |
| 700 | 1 | a Riboli, E.4 aut |
| 700 | 1 | a Bueno-De-Mesquita, B.4 aut |
| 710 | 2 | a Karolinska Institutetb Kirurgi4 org |
| 773 | 0 | t International Journal of Cancerd : Wileyg 131:7q 131:7x 0020-7136x 1097-0215 |
| 856 | 4 | u https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/ijc.27547 |
| 856 | 4 | u http://dx.doi.org/10.1002/ijc.27547y FULLTEXT |
| 856 | 4 8 | u https://gup.ub.gu.se/publication/162719 |
| 856 | 4 8 | u https://doi.org/10.1002/ijc.27547 |
| 856 | 4 8 | u https://lup.lub.lu.se/record/3073460 |
| 856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-57228 |
| 856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:125005121 |
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