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LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00003422naa a2200325 4500
001oai:lup.lub.lu.se:6aa6d2d7-91f8-4d95-a337-026045709a39
003SwePub
008160418s2016 | |||||||||||000 ||eng|
024a https://lup.lub.lu.se/record/6aa6d2d7-91f8-4d95-a337-026045709a392 URI
024a https://doi.org/10.3109/03009742.2016.11439652 DOI
040 a (SwePub)lu
041 a engb eng
042 9 SwePub
072 7a art2 swepub-publicationtype
072 7a ref2 swepub-contenttype
100a Cooper, A4 aut
2451 0a What PASSes for good? : Experience-based Swedish and hypothetical British EuroQol 5-Dimensions preference sets yield markedly different point estimates and patient acceptable symptom state cut-off values in chronic arthritis patients on TNF blockade
264 c 2016-03-30
264 1b Informa UK Limited,c 2016
300 a 4 s.
520 a OBJECTIVES: Health utilities derived from answers to generic health-related quality of life (HRQoL) questionnaires such as the EuroQol 5-Dimensions (EQ-5D) are often used in cost-utility analyses (CUAs) of new and expensive treatments. Different preference sets (tariffs) used in the computation of utility values and quality-adjusted life-years (QALYs) from questionnaire responses (health states) yield varying results, potentially affecting decisions of resource allocation. The objective of the present study was to compare British (UK), hypothetical, and Swedish (SE), experience-based, EQ-5D utilities using data from clinical practice.METHOD: UK and SE EQ-5D utilities were computed in an observational cohort of patients with rheumatoid arthritis (RA), spondyloarthritis (SpA), and psoriatic arthritis (PsA) treated with tumour necrosis factor (TNF) blockers, comparing point estimates and patient acceptable symptom state (PASS) cut-off levels.RESULTS: SE utilities were found to be consistently higher than UK utilities, and PASS cut-offs were essentially stable over time.CONCLUSIONS: With higher baseline utilities, there may be less room for improvement after an intervention and thus less accumulation of QALYs in CUAs applying the SE, as opposed to the UK, EQ-5D tariff.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Reumatologi och inflammation0 (SwePub)302102 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Rheumatology and Autoimmunity0 (SwePub)302102 hsv//eng
700a KARLSSON WALLMAN, JOHANu Lund University,Lunds universitet,Reumatologi och molekylär skelettbiologi,Sektion III,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Rheumatology,Section III,Department of Clinical Sciences, Lund,Faculty of Medicine4 aut0 (Swepub:lu)med-jnk
700a Gülfe, Au Lund University,Lunds universitet,Reumatologi och molekylär skelettbiologi,Sektion III,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Rheumatology,Section III,Department of Clinical Sciences, Lund,Faculty of Medicine4 aut0 (Swepub:lu)med-agf
710a Reumatologi och molekylär skelettbiologib Sektion III4 org
773t Scandinavian Journal of Rheumatologyd : Informa UK Limitedg 45:6, s. 470-473q 45:6<470-473x 1502-7732x 0300-9742
856u http://dx.doi.org/10.3109/03009742.2016.1143965y FULLTEXT
8564 8u https://lup.lub.lu.se/record/6aa6d2d7-91f8-4d95-a337-026045709a39
8564 8u https://doi.org/10.3109/03009742.2016.1143965

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Cooper, A
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