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Serum antibody levels and avidities to Escherichia coli O antigens and poliovirus type 1 antigen are increased in children treated for malignant disease.

Abrahamsson, Jonas, 1954 (author)
Gothenburg University,Göteborgs universitet,Institutionen för kvinnors och barns hälsa, Avdelningen för pediatrik,Institute for the Health of Women and Children, Dept of Paediatrics
Carlsson, Barbro (author)
Gothenburg University,Göteborgs universitet,Institutionen för laboratoriemedicin, Avdelningen för klinisk immunologi,Institute of Laboratory Medicine, Dept of Clinical Immunology
Mellander, Lotta, 1941 (author)
Gothenburg University,Göteborgs universitet,Institutionen för kvinnors och barns hälsa, Avdelningen för pediatrik,Institute for the Health of Women and Children, Dept of Paediatrics
 (creator_code:org_t)
1999
1999
English.
In: Medical and pediatric oncology. - 0098-1532. ; 32:6, s. 416-20
  • Journal article (peer-reviewed)
Abstract Subject headings
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  • Treatment of malignant disease in children is often associated with low serum immunoglobulin and reduced specific antibody levels. The aim of this study was to investigate if the functional affinity of specific antibodies in serum and saliva is reduced as well and to evaluate if antigenic exposure or treatment duration affects this antibody avidity.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Pediatrik (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Pediatrics (hsv//eng)

Keyword

Adolescent
Antibodies
Bacterial
blood
metabolism
Antibodies
Viral
blood
metabolism
Antibody Affinity
immunology
Antineoplastic Combined Chemotherapy Protocols
therapeutic use
Child
Child
Preschool
Escherichia coli O157
immunology
Female
Humans
Immunoglobulins
blood
metabolism
Male
Neoplasms
drug therapy
immunology
Poliovirus
immunology
Saliva
immunology

Publication and Content Type

ref (subject category)
art (subject category)

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University of Gothenburg

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