Search: onr:"swepub:oai:gup.ub.gu.se/200123" >
Infections With the...
-
Grankvist, AnnaGothenburg University,Göteborgs universitet,Institutionen för biomedicin, avdelningen för infektionssjukdomar,Institute of Biomedicine, Department of Infectious Medicine
(author)
Infections With the Tick-Borne Bacterium "Candidatus Neoehrlichia mikurensis" Mimic Noninfectious Conditions in Patients With B Cell Malignancies or Autoimmune Diseases
- Article/chapterEnglish2014
Publisher, publication year, extent ...
-
2014-03-18
-
Oxford University Press (OUP),2014
Numbers
-
LIBRIS-ID:oai:gup.ub.gu.se/200123
-
https://gup.ub.gu.se/publication/200123URI
-
https://doi.org/10.1093/cid/ciu189DOI
Supplementary language notes
Part of subdatabase
Classification
-
Subject category:ref swepub-contenttype
-
Subject category:art swepub-publicationtype
Notes
-
Background. Candidatus Neoehrlichia mikurensis is a newly discovered noncultivatable bacterium spread among ticks and rodents in Europe and Asia that can infect humans, particularly immunocompromised patients. Methods.aEuro integral We compiled clinical and laboratory data from 11 patients with hematological malignances or autoimmune diseases who were diagnosed with Candidatus N. mikurensis infection in Europe 2010-2013. Both published (6) and unpublished cases (5) were included. Results.aEuro integral The patients had a median age of 67, were mostly male (8/11), and resided in Sweden, Switzerland, Germany, and the Czech Republic. All but one had ongoing or recent immune suppressive treatment and a majority were splenectomized (8/11). Less than half of them recalled tick exposure. The most frequent symptoms were fever (11/11), localized pain afflicting muscles and/or joints (8/11), vascular and thromboembolic events (6/11), that is, deep vein thrombosis (4), transitory ischemic attacks (2), pulmonary embolism (1), and arterial aneurysm (1). Typical laboratory findings were elevated C-reactive protein, leukocytosis with neutrophilia, and anemia. Median time from onset of symptoms to correct diagnosis was 2 months. In at least 4 cases, the condition was interpreted to be due to the underlying disease, and immunosuppressive therapy was scheduled. All patients recovered completely when doxycycline was administered. Conclusions.aEuro integral Candidatus N. mikurensis is an emerging tick-borne pathogen that may give rise to a systemic inflammatory syndrome in persons with hematologic or autoimmune diseases that could be mistaken for recurrence of the underlying disease and/or unrelated arteriosclerotic vascular events. Awareness of this new pathogen is warranted among rheumatologists, hematologists, oncologists, and infectious disease specialists.
Subject headings and genre
Added entries (persons, corporate bodies, meetings, titles ...)
-
Andersson, P. O.
(author)
-
Mattsson, M.
(author)
-
Sender, M.
(author)
-
Vaht, K.
(author)
-
Hoper, L.
(author)
-
Sakiniene, E.
(author)
-
Trysberg, E.
(author)
-
Stenson, M.
(author)
-
Fehr, J.
(author)
-
Pekova, S.
(author)
-
Bogdan, C.
(author)
-
Bloemberg, G.
(author)
-
Wennerås, Christine,1963Gothenburg University,Göteborgs universitet,Institutionen för biomedicin, avdelningen för infektionssjukdomar,Institute of Biomedicine, Department of Infectious Medicine(Swepub:gu)xwennc
(author)
-
Göteborgs universitetInstitutionen för biomedicin, avdelningen för infektionssjukdomar
(creator_code:org_t)
Related titles
-
In:Clinical Infectious Diseases: Oxford University Press (OUP)58:12, s. 1716-17221058-48381537-6591
Internet link
Find in a library
To the university's database
- By the author/editor
-
Grankvist, Anna
-
Andersson, P. O.
-
Mattsson, M.
-
Sender, M.
-
Vaht, K.
-
Hoper, L.
-
show more...
-
Sakiniene, E.
-
Trysberg, E.
-
Stenson, M.
-
Fehr, J.
-
Pekova, S.
-
Bogdan, C.
-
Bloemberg, G.
-
Wennerås, Christ ...
-
show less...
- About the subject
-
- MEDICAL AND HEALTH SCIENCES
-
MEDICAL AND HEAL ...
-
and Basic Medicine
-
and Immunology in th ...
-
- MEDICAL AND HEALTH SCIENCES
-
MEDICAL AND HEAL ...
-
and Clinical Medicin ...
-
and Infectious Medic ...
- Articles in the publication
-
Clinical Infecti ...
- By the university
-
University of Gothenburg